STRINGSTRING
PDE4D PDE4D PLN PLN FKBP1B FKBP1B SPTBN4 SPTBN4 ADRA1A ADRA1A BIN1 BIN1 TRPV1 TRPV1 PDE5A PDE5A ATP1A1 ATP1A1 ATP1A2 ATP1A2 ATP2A2 ATP2A2 PIK3CG PIK3CG AGTR2 AGTR2 LOC108293848 LOC108293848 SRI SRI GRK2 GRK2 SPX SPX RNLS RNLS ZC3H12A ZC3H12A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDE4DPhosphodiesterase. (808 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2562 aa)
ADRA1AAdrenoceptor alpha 1A. (466 aa)
BIN1Bridging integrator 1. (593 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (839 aa)
PDE5APhosphodiesterase. (875 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
ATP1A2ATPase Na+/K+ transporting subunit alpha 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (631 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
PIK3CGUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1102 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
LOC108293848Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (854 aa)
SRISorcin. (198 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
SPXSpexin hormone. (116 aa)
RNLSAmino_oxidase domain-containing protein. (175 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (598 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
Server load: low (16%) [HD]