node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAD | DHODH | ENSCCAP00000038556 | ENSCCAP00000033109 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.990 |
CAD | DPYD | ENSCCAP00000038556 | ENSCCAP00000000698 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.902 |
CAD | DPYS | ENSCCAP00000038556 | ENSCCAP00000028142 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Dihydropyrimidinase. | 0.760 |
CAD | UCK1 | ENSCCAP00000038556 | ENSCCAP00000024437 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.642 |
CAD | UCK2 | ENSCCAP00000038556 | ENSCCAP00000003061 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.616 |
CAD | UCKL1 | ENSCCAP00000038556 | ENSCCAP00000013036 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.648 |
CAD | UMPS | ENSCCAP00000038556 | ENSCCAP00000035287 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Uridine monophosphate synthetase. | 0.905 |
CAD | UPP1 | ENSCCAP00000038556 | ENSCCAP00000022681 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.637 |
CAD | UPP2 | ENSCCAP00000038556 | ENSCCAP00000006377 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.637 |
CAD | UPRT | ENSCCAP00000038556 | ENSCCAP00000016989 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Uracil phosphoribosyltransferase homolog. | 0.672 |
CDA | CMPK1 | ENSCCAP00000024506 | ENSCCAP00000002155 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.492 |
CDA | DHODH | ENSCCAP00000024506 | ENSCCAP00000033109 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.663 |
CDA | DPYD | ENSCCAP00000024506 | ENSCCAP00000000698 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.644 |
CDA | NT5C | ENSCCAP00000024506 | ENSCCAP00000025735 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 5', 3'-nucleotidase, cytosolic. | 0.942 |
CDA | UCK1 | ENSCCAP00000024506 | ENSCCAP00000024437 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.972 |
CDA | UCK2 | ENSCCAP00000024506 | ENSCCAP00000003061 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.971 |
CDA | UCKL1 | ENSCCAP00000024506 | ENSCCAP00000013036 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.974 |
CDA | UMPS | ENSCCAP00000024506 | ENSCCAP00000035287 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uridine monophosphate synthetase. | 0.624 |
CDA | UPB1 | ENSCCAP00000024506 | ENSCCAP00000013128 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Beta-ureidopropionase 1. | 0.499 |
CDA | UPP1 | ENSCCAP00000024506 | ENSCCAP00000022681 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.991 |