(125 nodes) Camera-type eye morphogenesis network (Cebus capucinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LHX1	LIM homeobox 1. (406 aa)
	CRB1	Crumbs cell polarity complex component 1. (1406 aa)
	CDON	Cell adhesion associated, oncogene regulated. (1287 aa)
	NAGLU	N-acetyl-alpha-glucosaminidase. (742 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	SOX11	Transcription factor SOX. (450 aa)
	EPHA2	EPH receptor A2. (976 aa)
	SOX9	SRY-box transcription factor 9. (509 aa)
	FZD5	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
	ENSCCAP00000001843	Uncharacterized protein. (98 aa)
	NRL	Neural retina leucine zipper. (237 aa)
	IGSF22	Immunoglobulin superfamily member 22. (1325 aa)
	VSX1	Visual system homeobox 1. (364 aa)
	SDK2	Sidekick cell adhesion molecule 2. (2118 aa)
	THRB	Thyroid hormone receptor beta. (476 aa)
	LOC108289748	IRS-type PTB domain-containing protein. (526 aa)
	COL8A1	Collagen type VIII alpha 1 chain. (745 aa)
	FOXE3	Forkhead box E3. (319 aa)
	PROM1	Prominin 1. (865 aa)
	MAN2A1	Alpha-mannosidase. (1144 aa)
	ZHX2	Zinc fingers and homeoboxes 2. (837 aa)
	TOPORS	TOP1 binding arginine/serine rich protein. (1081 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (275 aa)
	PHACTR4	Phosphatase and actin regulator. (712 aa)
	SDK1	Sidekick cell adhesion molecule 1. (2215 aa)
	STRA6	Stimulated by retinoic acid 6. (706 aa)
	IGFN1	Uncharacterized protein. (1251 aa)
	RING1	Ring finger protein 1. (406 aa)
	MEIS1	Meis homeobox 1. (463 aa)
	PTF1A	Pancreas associated transcription factor 1a. (332 aa)
	AHI1	Abelson helper integration site 1. (1176 aa)
	TSPAN12	Tetraspanin. (305 aa)
	CALB1	Calbindin 1. (261 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
	BMP7	Bone morphogenetic protein 7. (430 aa)
	HCN1	Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (884 aa)
	NECTIN1	Nectin cell adhesion molecule 1. (516 aa)
	GNAT2	G protein subunit alpha transducin 2. (354 aa)
	ENSCCAP00000010320	Uncharacterized protein. (666 aa)
	VAX1	Ventral anterior homeobox 1. (334 aa)
	PDE6C	Phosphodiesterase. (858 aa)
	ROM1	Retinal outer segment membrane protein 1. (351 aa)
	FAT1	FAT atypical cadherin 1. (4589 aa)
	RDH13	Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa)
	LOC108298073	Uncharacterized protein. (985 aa)
	BAX	BCL2 associated X, apoptosis regulator. (159 aa)
	ENSCCAP00000012370	ANK_REP_REGION domain-containing protein. (518 aa)
	PITX3	Homeobox protein. (302 aa)
	SOX8	SRY-box transcription factor 8. (446 aa)
	SP3	Uncharacterized protein. (780 aa)
	HIPK1	Homeodomain interacting protein kinase 1. (1210 aa)
	CNTF	Ciliary neurotrophic factor. (200 aa)
	SLC1A1	Amino acid transporter. (524 aa)
	EPHB1	EPH receptor B1. (984 aa)
	BBS4	Bardet-Biedl syndrome 4. (494 aa)
	TBC1D20	TBC1 domain family member 20. (403 aa)
	SIX3	SIX homeobox 3. (331 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	RPGRIP1L	RPGRIP1 like. (1269 aa)
	STAT3	Signal transducer and activator of transcription. (770 aa)
	MFN2	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
	PITX2	Homeobox protein. (325 aa)
	ENSCCAP00000018987	Uncharacterized protein. (699 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
	CABP4	Calcium binding protein 4. (272 aa)
	NF1	Neurofibromin 1. (2839 aa)
	PAX6	Paired box 6. (447 aa)
	RORB	RAR related orphan receptor B. (470 aa)
	ABI2	Abl interactor 2. (507 aa)
	AQP5	Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
	TENM3	Teneurin transmembrane protein 3. (2699 aa)
	ALDH1A3	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
	SKI	SKI proto-oncogene. (729 aa)
	RPE65	Retinoid isomerohydrolase RPE65. (533 aa)
	TTC8	Tetratricopeptide repeat domain 8. (515 aa)
	HIF1A	Uncharacterized protein. (848 aa)
	MEGF11	Multiple EGF like domains 11. (1140 aa)
	TH	Tyrosine hydroxylase. (527 aa)
	FAT3	FAT atypical cadherin 3. (4557 aa)
	C12orf57	Chromosome 12 open reading frame 57. (97 aa)
	GLI3	GLI family zinc finger 3. (1577 aa)
	RP1	RP1 axonemal microtubule associated. (2030 aa)
	THY1	Thy-1 cell surface antigen. (161 aa)
	MFSD2A	Major facilitator superfamily domain containing 2A. (543 aa)
	PTPRM	Protein tyrosine phosphatase receptor type M. (1465 aa)
	WNT2B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
	USH1C	USH1 protein network component harmonin. (899 aa)
	ZEB1	Zinc finger E-box binding homeobox 1. (1124 aa)
	KDM2B	Lysine demethylase 2B. (1349 aa)
	WNT9A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
	NECTIN3	Nectin cell adhesion molecule 3. (549 aa)
	LOC108293547	Uncharacterized protein. (773 aa)
	OBSL1	Obscurin like 1. (1896 aa)
	GDF11	Growth differentiation factor 11. (407 aa)
	IMPG2	Interphotoreceptor matrix proteoglycan 2. (1197 aa)
	CRB2	Crumbs cell polarity complex component 2. (1291 aa)
	FOXF2	Forkhead box F2. (456 aa)
	TDRD7	Tudor domain containing 7. (972 aa)
	FOXN4	Forkhead box N4. (517 aa)
	NTRK2	Tyrosine-protein kinase receptor. (838 aa)
	RPGRIP1	RPGR interacting protein 1. (1250 aa)
	ATP8A2	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1188 aa)
	COL8A2	Collagen type VIII alpha 2 chain. (721 aa)
	NOTCH1	Notch receptor 1. (2550 aa)
	IFT122	Intraflagellar transport 122. (1269 aa)
	HIPK2	Homeodomain interacting protein kinase 2. (1189 aa)
	PROX1	Prospero homeobox 1. (737 aa)
	WNT16	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
	PAX2	Paired box 2. (417 aa)
	TBX2	T-box transcription factor 2. (713 aa)
	IFT172	Uncharacterized protein. (1602 aa)
	BCAR3	BCAR3 adaptor protein, NSP family member. (824 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	TFAP2B	Transcription factor AP-2 beta. (460 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
	TFAP2A	Transcription factor AP-2 alpha. (439 aa)
	LOC108301643	Uncharacterized protein. (400 aa)
	LOC108289749	Fibroblast growth factor receptor substrate 2. (508 aa)
	AQP1	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
	RS1	Retinoschisin 1. (224 aa)
	ATF4	Activating transcription factor 4. (351 aa)
	ENSCCAP00000039965	Uncharacterized protein. (374 aa)
	EPHB2	EPH receptor B2. (1103 aa)
	BAK1	BCL2 antagonist/killer 1. (211 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHI1	RPGRIP1	ENSCCAP00000007565	ENSCCAP00000031556	Abelson helper integration site 1.	RPGR interacting protein 1.	0.410
AHI1	RPGRIP1L	ENSCCAP00000007565	ENSCCAP00000017385	Abelson helper integration site 1.	RPGRIP1 like.	0.593
ALDH1A3	RDH13	ENSCCAP00000020875	ENSCCAP00000011765	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.428
ALDH1A3	STRA6	ENSCCAP00000020875	ENSCCAP00000005619	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Stimulated by retinoic acid 6.	0.406
AQP1	AQP5	ENSCCAP00000038868	ENSCCAP00000020500	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.444
AQP5	AQP1	ENSCCAP00000020500	ENSCCAP00000038868	Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.444
ATP8A2	RPGRIP1L	ENSCCAP00000032568	ENSCCAP00000017385	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	RPGRIP1 like.	0.556
BAK1	BAX	ENSCCAP00000040261	ENSCCAP00000011956	BCL2 antagonist/killer 1.	BCL2 associated X, apoptosis regulator.	0.955
BAK1	MFN2	ENSCCAP00000040261	ENSCCAP00000018067	BCL2 antagonist/killer 1.	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.446
BAX	BAK1	ENSCCAP00000011956	ENSCCAP00000040261	BCL2 associated X, apoptosis regulator.	BCL2 antagonist/killer 1.	0.955
BBS4	ENSCCAP00000039965	ENSCCAP00000014204	ENSCCAP00000039965	Bardet-Biedl syndrome 4.	Uncharacterized protein.	0.412
BBS4	IFT122	ENSCCAP00000014204	ENSCCAP00000033399	Bardet-Biedl syndrome 4.	Intraflagellar transport 122.	0.595
BBS4	IFT172	ENSCCAP00000014204	ENSCCAP00000036466	Bardet-Biedl syndrome 4.	Uncharacterized protein.	0.412
BBS4	LOC108301643	ENSCCAP00000014204	ENSCCAP00000037768	Bardet-Biedl syndrome 4.	Uncharacterized protein.	0.412
BBS4	RPGRIP1L	ENSCCAP00000014204	ENSCCAP00000017385	Bardet-Biedl syndrome 4.	RPGRIP1 like.	0.461
BBS4	TTC8	ENSCCAP00000014204	ENSCCAP00000021600	Bardet-Biedl syndrome 4.	Tetratricopeptide repeat domain 8.	0.989
BCAR3	PTPRM	ENSCCAP00000036480	ENSCCAP00000025577	BCAR3 adaptor protein, NSP family member.	Protein tyrosine phosphatase receptor type M.	0.447
BMP4	BMP7	ENSCCAP00000036602	ENSCCAP00000008930	Bone morphogenetic protein 4.	Bone morphogenetic protein 7.	0.809
BMP4	CNTF	ENSCCAP00000036602	ENSCCAP00000013833	Bone morphogenetic protein 4.	Ciliary neurotrophic factor.	0.661
BMP4	FOXF2	ENSCCAP00000036602	ENSCCAP00000030265	Bone morphogenetic protein 4.	Forkhead box F2.	0.407