STRINGSTRING
PLS1 PLS1 RAG2 RAG2 SPTBN4 SPTBN4 SEMA4D SEMA4D ITSN2 ITSN2 WNT3A WNT3A SMO SMO HOPX HOPX LIMK1 LIMK1 YBX3 YBX3 MEF2C MEF2C TSHR TSHR DRD2 DRD2 EDN1 EDN1 RPS6KB1 RPS6KB1 RUFY3 RUFY3 BCL2 BCL2 MUL1 MUL1 PLAA PLAA PLCB1 PLCB1 CXCL12 CXCL12 GOLGA4 GOLGA4 FN1 FN1 MEGF8 MEGF8 FGF9 FGF9 GATA6 GATA6 TRPC5 TRPC5 CDH4 CDH4 DLL1 DLL1 GHRL GHRL TGFBR2 TGFBR2 BMP10 BMP10 LPAR3 LPAR3 TRPV2 TRPV2 INSR INSR ARX ARX LOC108298073 LOC108298073 SLC6A3 SLC6A3 POU4F2 POU4F2 WT1 WT1 PRKN PRKN SEMA7A SEMA7A CREB1 CREB1 DBNL DBNL BBS4 BBS4 BMPR2 BMPR2 HMGA2 HMGA2 ACACB ACACB CPNE9 CPNE9 REG1B REG1B CPNE5 CPNE5 PEX5 PEX5 MAP1B MAP1B TBX5 TBX5 RNF157 RNF157 AKAP6 AKAP6 CHD7 CHD7 SYT4 SYT4 GLI1 GLI1 MKKS MKKS VIL1 VIL1 IGF2 IGF2 SOX15 SOX15 CRABP2 CRABP2 EFNA5 EFNA5 GPAM GPAM ZFYVE27 ZFYVE27 GHR GHR SLC23A2 SLC23A2 CSF1 CSF1 GHSR GHSR SYT2 SYT2 FGF8 FGF8 FGFR2 FGFR2 CDKL5 CDKL5 SEMA5A SEMA5A EZR EZR PIM1 PIM1 RND2 RND2 ENSCCAP00000023346 ENSCCAP00000023346 TGFBR3 TGFBR3 WNT3 WNT3 RIMS1 RIMS1 ENSCCAP00000024566 ENSCCAP00000024566 TBX20 TBX20 NTN1 NTN1 CAPN3 CAPN3 AGRN AGRN MAPK14 MAPK14 RIMS1-2 RIMS1-2 ZFPM2 ZFPM2 WNT2 WNT2 LEP LEP ACTN3 ACTN3 SHTN1 SHTN1 L1CAM L1CAM CYFIP1 CYFIP1 IL7 IL7 SYT17 SYT17 BBS2 BBS2 NOL12 NOL12 SMAD7 SMAD7 GHRHR GHRHR CACNG7 CACNG7 MACF1 MACF1 DISC1 DISC1 MAP3K13 MAP3K13 LOC108287611 LOC108287611 ATP8A2 ATP8A2 DBN1 DBN1 ADNP ADNP GHRH GHRH PPARD PPARD MAPT MAPT NOTCH1 NOTCH1 BMPR1A BMPR1A YAP1 YAP1 PROX1 PROX1 AKT1 AKT1 NRG1 NRG1 ANAPC2 ANAPC2 STAT5B STAT5B HEY2 HEY2 TBX2 TBX2 HLX HLX MYOD1 MYOD1 IGF1 IGF1 ERBB4 ERBB4 LOC108282374 LOC108282374 SASH3 SASH3 NIPBL NIPBL TWF2 TWF2 SYT3 SYT3 RASAL1 RASAL1 PPIB PPIB BCL11A BCL11A RIMS2 RIMS2 NRP1 NRP1 UNC13A UNC13A SRF SRF BDNF BDNF AGR2 AGR2 SMURF1 SMURF1 PARP2 PARP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLS1Uncharacterized protein. (629 aa)
RAG2Recombination activating 2. (527 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2562 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
ITSN2Intersectin 2. (1686 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
HOPXHOP homeobox. (90 aa)
LIMK1LIM domain kinase 1. (625 aa)
YBX3Y-box binding protein 3. (372 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
EDN1Endothelin 1. (212 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
RUFY3RUN and FYVE domain containing 3. (603 aa)
BCL2BCL2 apoptosis regulator. (240 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
PLAAPhospholipase A2 activating protein. (803 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1215 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
GOLGA4Golgin A4. (2244 aa)
FN1Fibronectin 1. (2478 aa)
MEGF8Multiple EGF like domains 8. (2855 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
GATA6GATA binding protein 6. (592 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
CDH4Cadherin 4; Cadherins are calcium-dependent cell adhesion proteins. (916 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (353 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (765 aa)
INSRTyrosine-protein kinase receptor. (1352 aa)
ARXAristaless related homeobox. (562 aa)
LOC108298073Uncharacterized protein. (985 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (687 aa)
POU4F2POU domain protein. (408 aa)
WT1WT1 transcription factor. (517 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (661 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
DBNLDrebrin like. (440 aa)
BBS4Bardet-Biedl syndrome 4. (494 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (961 aa)
HMGA2Uncharacterized protein. (118 aa)
ACACBAcetyl-CoA carboxylase beta. (2458 aa)
CPNE9Copine family member 9. (553 aa)
REG1BRegenerating family member 1 beta. (166 aa)
CPNE5Copine 5. (593 aa)
PEX5TPR_REGION domain-containing protein. (639 aa)
MAP1BMicrotubule associated protein 1B. (2465 aa)
TBX5T-box transcription factor 5. (518 aa)
RNF157Ring finger protein 157. (591 aa)
AKAP6A-kinase anchoring protein 6. (2241 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2996 aa)
SYT4Synaptotagmin 4. (425 aa)
GLI1GLI family zinc finger 1. (1106 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
VIL1Villin 1. (558 aa)
IGF2Insulin like growth factor 2. (236 aa)
SOX15SRY-box transcription factor 15. (233 aa)
CRABP2Cellular retinoic acid binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
ZFYVE27Zinc finger FYVE-type containing 27. (475 aa)
GHRGrowth hormone receptor. (638 aa)
SLC23A2Solute carrier family 23 member 2. (651 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (551 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
SYT2Synaptotagmin 2. (421 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
FGFR2Fibroblast growth factor receptor. (782 aa)
CDKL5Cyclin dependent kinase like 5. (1031 aa)
SEMA5ASemaphorin 5A. (1074 aa)
EZREzrin. (596 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa)
RND2Rho family GTPase 2. (227 aa)
ENSCCAP00000023346Uncharacterized protein. (418 aa)
TGFBR3Transforming growth factor beta receptor 3. (851 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1534 aa)
ENSCCAP00000024566Uncharacterized protein. (133 aa)
TBX20T-box transcription factor 20. (447 aa)
NTN1Netrin 1. (604 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (816 aa)
AGRNAgrin. (2045 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
RIMS1-2RabBD domain-containing protein. (159 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (936 aa)
SHTN1Shootin 1. (631 aa)
L1CAML1 cell adhesion molecule. (1252 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (177 aa)
SYT17Synaptotagmin 17. (505 aa)
BBS2Bardet-Biedl syndrome 2. (614 aa)
NOL12Uncharacterized protein. (210 aa)
SMAD7Mothers against decapentaplegic homolog. (480 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
MACF1Microtubule actin crosslinking factor 1. (7591 aa)
DISC1DISC1 scaffold protein. (852 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (965 aa)
LOC108287611Uncharacterized protein. (205 aa)
ATP8A2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1188 aa)
DBN1Drebrin 1. (697 aa)
ADNPActivity dependent neuroprotector homeobox. (1103 aa)
GHRHGrowth hormone releasing hormone. (107 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
MAPTMicrotubule-associated protein. (766 aa)
NOTCH1Notch receptor 1. (2550 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (432 aa)
YAP1Uncharacterized protein. (506 aa)
PROX1Prospero homeobox 1. (737 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa)
NRG1Neuregulin 1. (713 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (823 aa)
STAT5BSignal transducer and activator of transcription. (788 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
TBX2T-box transcription factor 2. (713 aa)
HLXH2.0 like homeobox. (492 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
IGF1Insulin like growth factor 1. (199 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
LOC108282374Uncharacterized protein. (330 aa)
SASH3SAM and SH3 domain containing 3. (380 aa)
NIPBLNipped-B protein. (2814 aa)
TWF2Twinfilin actin binding protein 2. (349 aa)
SYT3Synaptotagmin 3. (528 aa)
RASAL1RAS protein activator like 1. (806 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (835 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1349 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (927 aa)
UNC13AUnc-13 homolog A. (1723 aa)
SRFSerum response factor. (509 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (329 aa)
AGR2Anterior gradient 2, protein disulphide isomerase family member. (183 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
PARP2Poly [ADP-ribose] polymerase. (570 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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