(35 nodes) Animal organ formation network (Cebus capucinus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	LRP2	LDL receptor related protein 2. (4656 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	RDH10	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
	PAX2	Paired box 2. (417 aa)
	TBR1	T-box brain transcription factor 1. (682 aa)
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (432 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (464 aa)
	SOX17	SRY-box transcription factor 17. (408 aa)
	SELENOH	Selenoprotein H. (121 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
	GLI3	GLI family zinc finger 3. (1577 aa)
	FGFR2	Fibroblast growth factor receptor. (782 aa)
	EMP2	Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
	TP63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
	RBM20	RNA binding motif protein 20. (1228 aa)
	FOXH1	Forkhead box H1. (365 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	ENSCCAP00000015218	Folate_rec domain-containing protein. (228 aa)
	MESP1	Mesoderm posterior bHLH transcription factor 1. (257 aa)
	MAPK1	Mitogen-activated protein kinase. (366 aa)
	HOXA3	Homeobox A3. (444 aa)
	AXIN2	Axin 2. (842 aa)
	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (475 aa)
	AR	Androgen receptor. (887 aa)
	TGFBR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
	GATA6	GATA binding protein 6. (592 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	ISL1	ISL LIM homeobox 1. (349 aa)
	MEF2C	Myocyte enhancer factor 2C. (483 aa)
	NKX3-2	NK3 homeobox 2. (333 aa)
	LEMD2	LEM domain containing 2. (503 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	CTNNB1	ENSCCAP00000010284	ENSCCAP00000015925	Androgen receptor.	Catenin beta 1.	0.925
AXIN2	BMP4	ENSCCAP00000010720	ENSCCAP00000036602	Axin 2.	Bone morphogenetic protein 4.	0.413
AXIN2	CTNNB1	ENSCCAP00000010720	ENSCCAP00000015925	Axin 2.	Catenin beta 1.	0.995
AXIN2	FGFR2	ENSCCAP00000010720	ENSCCAP00000022112	Axin 2.	Fibroblast growth factor receptor.	0.645
AXIN2	LRP2	ENSCCAP00000010720	ENSCCAP00000032448	Axin 2.	LDL receptor related protein 2.	0.537
AXIN2	WNT11	ENSCCAP00000010720	ENSCCAP00000001059	Axin 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.456
AXIN2	WNT5A	ENSCCAP00000010720	ENSCCAP00000017316	Axin 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.505
BMP4	AXIN2	ENSCCAP00000036602	ENSCCAP00000010720	Bone morphogenetic protein 4.	Axin 2.	0.413
BMP4	BMPR1A	ENSCCAP00000036602	ENSCCAP00000033496	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.995
BMP4	FGF10	ENSCCAP00000036602	ENSCCAP00000025026	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.520
BMP4	FGFR2	ENSCCAP00000036602	ENSCCAP00000022112	Bone morphogenetic protein 4.	Fibroblast growth factor receptor.	0.454
BMP4	GATA6	ENSCCAP00000036602	ENSCCAP00000008059	Bone morphogenetic protein 4.	GATA binding protein 6.	0.471
BMP4	NOG	ENSCCAP00000036602	ENSCCAP00000005156	Bone morphogenetic protein 4.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.997
BMP4	SHH	ENSCCAP00000036602	ENSCCAP00000032826	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.554
BMP4	SOX17	ENSCCAP00000036602	ENSCCAP00000032298	Bone morphogenetic protein 4.	SRY-box transcription factor 17.	0.638
BMP4	TGFBR2	ENSCCAP00000036602	ENSCCAP00000009387	Bone morphogenetic protein 4.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.478
BMPR1A	BMP4	ENSCCAP00000033496	ENSCCAP00000036602	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.995
BMPR1A	NOG	ENSCCAP00000033496	ENSCCAP00000005156	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.508
BMPR1A	TGFBR2	ENSCCAP00000033496	ENSCCAP00000009387	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.731
CTNNB1	AR	ENSCCAP00000015925	ENSCCAP00000010284	Catenin beta 1.	Androgen receptor.	0.925