(25 nodes) Regulation of astrocyte differentiation network (Cebus capucinus)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	EPHA4	EPH receptor A4. (949 aa)
	BIN1	Bridging integrator 1. (593 aa)
	MBD1	Methyl-CpG binding domain protein 1. (732 aa)
	NOTCH1	Notch receptor 1. (2550 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (464 aa)
	CNTN2	Contactin 2. (1046 aa)
	NR2E1	Nuclear receptor subfamily 2 group E member 1. (421 aa)
	CLCF1	Cardiotrophin like cytokine factor 1. (225 aa)
	NR1D1	Nuclear receptor subfamily 1 group D member 1. (615 aa)
	GPR37L1	G protein-coupled receptor 37 like 1. (481 aa)
	LIF	LIF interleukin 6 family cytokine. (202 aa)
	MAG	Myelin associated glycoprotein. (626 aa)
	TTBK1	Tau tubulin kinase 1. (1322 aa)
	SERPINE2	Serpin family E member 2; Belongs to the serpin family. (409 aa)
	F2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
	NF1	Neurofibromin 1. (2839 aa)
	HES5	Hes family bHLH transcription factor 5. (162 aa)
	ID4	Inhibitor of DNA binding 4, HLH protein. (161 aa)
	PRPF19	Pre-mRNA processing factor 19. (504 aa)
	HMGA2	Uncharacterized protein. (118 aa)
	LDLR	Low density lipoprotein receptor. (934 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (230 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	BMP2	Bone morphogenetic protein 2. (396 aa)
	IL6ST	Interleukin 6 signal transducer. (919 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP2	NOG	ENSCCAP00000003018	ENSCCAP00000005156	Bone morphogenetic protein 2.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.996
BMP2	SHH	ENSCCAP00000003018	ENSCCAP00000032826	Bone morphogenetic protein 2.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.417
CLCF1	IL6ST	ENSCCAP00000031228	ENSCCAP00000001282	Cardiotrophin like cytokine factor 1.	Interleukin 6 signal transducer.	0.953
F2	SERPINE2	ENSCCAP00000021735	ENSCCAP00000022198	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin family E member 2; Belongs to the serpin family.	0.969
HES5	NOTCH1	ENSCCAP00000018309	ENSCCAP00000033380	Hes family bHLH transcription factor 5.	Notch receptor 1.	0.550
IL6ST	CLCF1	ENSCCAP00000001282	ENSCCAP00000031228	Interleukin 6 signal transducer.	Cardiotrophin like cytokine factor 1.	0.953
IL6ST	LIF	ENSCCAP00000001282	ENSCCAP00000027539	Interleukin 6 signal transducer.	LIF interleukin 6 family cytokine.	0.996
LIF	IL6ST	ENSCCAP00000027539	ENSCCAP00000001282	LIF interleukin 6 family cytokine.	Interleukin 6 signal transducer.	0.996
NOG	BMP2	ENSCCAP00000005156	ENSCCAP00000003018	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Bone morphogenetic protein 2.	0.996
NOG	SHH	ENSCCAP00000005156	ENSCCAP00000032826	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.586
NOTCH1	HES5	ENSCCAP00000033380	ENSCCAP00000018309	Notch receptor 1.	Hes family bHLH transcription factor 5.	0.550
SERPINE2	F2	ENSCCAP00000022198	ENSCCAP00000021735	Serpin family E member 2; Belongs to the serpin family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.969
SHH	BMP2	ENSCCAP00000032826	ENSCCAP00000003018	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Bone morphogenetic protein 2.	0.417
SHH	NOG	ENSCCAP00000032826	ENSCCAP00000005156	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.586