STRINGSTRING
SMO SMO PTEN PTEN UCHL5 UCHL5 GSX2 GSX2 SLIT1 SLIT1 WNT5A WNT5A NF1 NF1 FGF8 FGF8 HESX1 HESX1 DUOX2 DUOX2 GDF7 GDF7 OTX1 OTX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (396 aa)
GSX2GS homeobox 2. (305 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
NF1Neurofibromin 1. (2839 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
HESX1HESX homeobox 1. (185 aa)
DUOX2Dual oxidase 2. (1546 aa)
GDF7Growth differentiation factor 7. (455 aa)
OTX1Orthodenticle homeobox 1. (355 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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