36 items (Cebus capucinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108293227	Uncharacterized protein. (819 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
	BBS1	BBS1 domain-containing protein. (593 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	AKT3	AKT serine/threonine kinase 3. (472 aa)
	UCHL5	Ubiquitin carboxyl-terminal hydrolase. (396 aa)
	GSX2	GS homeobox 2. (305 aa)
	SLIT1	Slit guidance ligand 1. (1534 aa)
	SLC6A4	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
	BBS4	Bardet-Biedl syndrome 4. (494 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1329 aa)
	MKKS	McKusick-Kaufman syndrome. (570 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	FANCC	Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (558 aa)
	NF1	Neurofibromin 1. (2839 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	ENSCCAP00000021490	WD_REPEATS_REGION domain-containing protein. (470 aa)
	CTNNA1	Catenin alpha 1. (905 aa)
	HESX1	HESX homeobox 1. (185 aa)
	CTNNA2	Catenin alpha 2. (953 aa)
	FZD3	Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
	SPEF2	Sperm flagellar 2. (1822 aa)
	VPS51	VPS51 subunit of GARP complex. (807 aa)
	SHANK3	SH3 and multiple ankyrin repeat domains 3. (1732 aa)
	BBS2	Bardet-Biedl syndrome 2. (614 aa)
	DUOX2	Dual oxidase 2. (1546 aa)
	FBXW11	F-box and WD repeat domain containing 11. (542 aa)
	EMX1	Empty spiracles homeobox 1. (290 aa)
	PAFAH1B1	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
	GDF7	Growth differentiation factor 7. (455 aa)
	PAX2	Paired box 2. (417 aa)
	FANCD2	FA complementation group D2. (1442 aa)
	PSEN1	Presenilin 1. (419 aa)
	SLC4A10	Anion exchange protein. (1140 aa)
	ZNF335	Zinc finger protein 335. (1343 aa)
	OTX1	Orthodenticle homeobox 1. (355 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT3	PTEN	ENSCCAP00000010520	ENSCCAP00000007387	AKT serine/threonine kinase 3.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.703
BBS1	BBS2	ENSCCAP00000006504	ENSCCAP00000030645	BBS1 domain-containing protein.	Bardet-Biedl syndrome 2.	0.993
BBS1	BBS4	ENSCCAP00000006504	ENSCCAP00000014204	BBS1 domain-containing protein.	Bardet-Biedl syndrome 4.	0.992
BBS1	MKKS	ENSCCAP00000006504	ENSCCAP00000016549	BBS1 domain-containing protein.	McKusick-Kaufman syndrome.	0.400
BBS1	SMO	ENSCCAP00000006504	ENSCCAP00000002443	BBS1 domain-containing protein.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.778
BBS2	BBS1	ENSCCAP00000030645	ENSCCAP00000006504	Bardet-Biedl syndrome 2.	BBS1 domain-containing protein.	0.993
BBS2	BBS4	ENSCCAP00000030645	ENSCCAP00000014204	Bardet-Biedl syndrome 2.	Bardet-Biedl syndrome 4.	0.995
BBS2	MKKS	ENSCCAP00000030645	ENSCCAP00000016549	Bardet-Biedl syndrome 2.	McKusick-Kaufman syndrome.	0.422
BBS2	SMO	ENSCCAP00000030645	ENSCCAP00000002443	Bardet-Biedl syndrome 2.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.670
BBS4	BBS1	ENSCCAP00000014204	ENSCCAP00000006504	Bardet-Biedl syndrome 4.	BBS1 domain-containing protein.	0.992
BBS4	BBS2	ENSCCAP00000014204	ENSCCAP00000030645	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 2.	0.995
BBS4	SMO	ENSCCAP00000014204	ENSCCAP00000002443	Bardet-Biedl syndrome 4.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.654
CTNNA1	CTNNA2	ENSCCAP00000022085	ENSCCAP00000023905	Catenin alpha 1.	Catenin alpha 2.	0.913
CTNNA2	CTNNA1	ENSCCAP00000023905	ENSCCAP00000022085	Catenin alpha 2.	Catenin alpha 1.	0.913
CTNNA2	LOC108293227	ENSCCAP00000023905	ENSCCAP00000000935	Catenin alpha 2.	Uncharacterized protein.	0.913
FANCC	FANCD2	ENSCCAP00000017645	ENSCCAP00000037517	Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.	FA complementation group D2.	0.991
FANCD2	FANCC	ENSCCAP00000037517	ENSCCAP00000017645	FA complementation group D2.	Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.	0.991
FZD3	WNT5A	ENSCCAP00000025112	ENSCCAP00000017316	Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.981
LOC108293227	CTNNA2	ENSCCAP00000000935	ENSCCAP00000023905	Uncharacterized protein.	Catenin alpha 2.	0.913
MKKS	BBS1	ENSCCAP00000016549	ENSCCAP00000006504	McKusick-Kaufman syndrome.	BBS1 domain-containing protein.	0.400