(15 nodes) Peripheral nervous system neuron development network (Cebus capucinus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HOXD10	Homeobox D10. (340 aa)
	ETV1	ETS variant 1. (505 aa)
	NTRK2	Tyrosine-protein kinase receptor. (838 aa)
	SLC25A46	Solute carrier family 25 member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (417 aa)
	PMP22	Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
	RUNX1	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
	ISL2	ISL LIM homeobox 2. (359 aa)
	HAND2	Heart and neural crest derivatives expressed 2. (217 aa)
	POU4F1	POU domain protein. (404 aa)
	NEFH	Neurofilament heavy; Belongs to the intermediate filament family. (944 aa)
	HOXD9	Homeobox D9. (355 aa)
	ASCL1	Achaete-scute family bHLH transcription factor 1. (233 aa)
	ONECUT2	One cut domain family member. (504 aa)
	ISL1	ISL LIM homeobox 1. (349 aa)
	RUNX3	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (430 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASCL1	ISL1	ENSCCAP00000005763	ENSCCAP00000005089	Achaete-scute family bHLH transcription factor 1.	ISL LIM homeobox 1.	0.525
ASCL1	ISL2	ENSCCAP00000005763	ENSCCAP00000027237	Achaete-scute family bHLH transcription factor 1.	ISL LIM homeobox 2.	0.525
ETV1	RUNX1	ENSCCAP00000035727	ENSCCAP00000028867	ETS variant 1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.433
ETV1	RUNX3	ENSCCAP00000035727	ENSCCAP00000006499	ETS variant 1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.469
HAND2	ISL1	ENSCCAP00000020234	ENSCCAP00000005089	Heart and neural crest derivatives expressed 2.	ISL LIM homeobox 1.	0.471
HAND2	ISL2	ENSCCAP00000020234	ENSCCAP00000027237	Heart and neural crest derivatives expressed 2.	ISL LIM homeobox 2.	0.416
HOXD10	HOXD9	ENSCCAP00000006005	ENSCCAP00000006506	Homeobox D10.	Homeobox D9.	0.793
HOXD9	HOXD10	ENSCCAP00000006506	ENSCCAP00000006005	Homeobox D9.	Homeobox D10.	0.793
ISL1	ASCL1	ENSCCAP00000005089	ENSCCAP00000005763	ISL LIM homeobox 1.	Achaete-scute family bHLH transcription factor 1.	0.525
ISL1	HAND2	ENSCCAP00000005089	ENSCCAP00000020234	ISL LIM homeobox 1.	Heart and neural crest derivatives expressed 2.	0.471
ISL2	ASCL1	ENSCCAP00000027237	ENSCCAP00000005763	ISL LIM homeobox 2.	Achaete-scute family bHLH transcription factor 1.	0.525
ISL2	HAND2	ENSCCAP00000027237	ENSCCAP00000020234	ISL LIM homeobox 2.	Heart and neural crest derivatives expressed 2.	0.416
RUNX1	ETV1	ENSCCAP00000028867	ENSCCAP00000035727	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	ETS variant 1.	0.433
RUNX1	RUNX3	ENSCCAP00000028867	ENSCCAP00000006499	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.560
RUNX3	ETV1	ENSCCAP00000006499	ENSCCAP00000035727	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	ETS variant 1.	0.469
RUNX3	RUNX1	ENSCCAP00000006499	ENSCCAP00000028867	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.560