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PLN | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa) | ||||
CD19 | CD19 molecule. (559 aa) | ||||
FKBP1B | Peptidylprolyl isomerase. (108 aa) | ||||
TRDN | Triadin. (722 aa) | ||||
CEMIP | Cell migration inducing hyaluronidase 1. (1361 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa) | ||||
NOS1 | Nitric oxide synthase 1. (1468 aa) | ||||
CASQ2 | Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (402 aa) | ||||
NTSR1 | Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (415 aa) | ||||
APLNR | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa) | ||||
TPCN1 | Two pore segment channel 1. (888 aa) | ||||
JPH3 | Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (748 aa) | ||||
ASPH | Aspartate beta-hydroxylase. (606 aa) | ||||
P2RY6 | Pyrimidinergic receptor P2Y6. (328 aa) | ||||
CLIC2 | Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa) | ||||
LACRT | Lacritin. (137 aa) | ||||
HTR2A | 5-hydroxytryptamine receptor 2A. (471 aa) | ||||
PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) | ||||
CYBA | Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (193 aa) | ||||
MCOLN2 | Mucolipin 2. (574 aa) | ||||
PDE4D | Phosphodiesterase. (808 aa) | ||||
CORO1A | Coronin; Belongs to the WD repeat coronin family. (461 aa) | ||||
ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) | ||||
SLC25A23 | Solute carrier family 25 member 23; Belongs to the mitochondrial carrier (TC 2.A.29) family. (468 aa) | ||||
UBASH3B | Ubiquitin associated and SH3 domain containing B. (649 aa) | ||||
LETM1 | Leucine zipper and EF-hand containing transmembrane protein 1. (739 aa) | ||||
RYR1 | Ryanodine receptor 1. (4990 aa) | ||||
JSRP1 | Junctional sarcoplasmic reticulum protein 1. (337 aa) | ||||
LOC108313439 | Protein kinase domain-containing protein. (247 aa) | ||||
DIAPH1 | Diaphanous related formin 1. (1206 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (159 aa) | ||||
JPH1 | Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa) | ||||
LOC108315475 | C2 domain-containing protein. (141 aa) | ||||
CXCL11 | C-X-C motif chemokine. (94 aa) | ||||
ABL1 | Tyrosine-protein kinase. (1149 aa) | ||||
CXCL9 | C-X-C motif chemokine. (129 aa) | ||||
NOL3 | Nucleolar protein 3. (258 aa) | ||||
CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa) | ||||
SLC8B1 | Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (584 aa) | ||||
LOC108318662 | Uncharacterized protein. (762 aa) | ||||
AKAP6 | A-kinase anchoring protein 6. (2241 aa) | ||||
CHD7 | Chromodomain helicase DNA binding protein 7. (2996 aa) | ||||
LYN | Tyrosine-protein kinase. (491 aa) | ||||
SRI | Sorcin. (198 aa) | ||||
BBC3 | BCL2 binding component 3. (261 aa) | ||||
IBTK | Inhibitor of Bruton tyrosine kinase. (1353 aa) | ||||
ANK2 | Ankyrin 2. (3955 aa) | ||||
PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (990 aa) | ||||
FLNA | Filamin A. (2192 aa) | ||||
JPH4 | Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa) | ||||
HTR2B | 5-hydroxytryptamine receptor 2B. (481 aa) | ||||
LOC108294424 | EF-hand domain-containing protein. (488 aa) | ||||
TMEM38A | Transmembrane protein 38A. (300 aa) | ||||
DMD | Dystrophin. (3686 aa) | ||||
F2 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa) | ||||
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2720 aa) | ||||
ENSCCAP00000022396 | Peptidylprolyl isomerase. (103 aa) | ||||
LIME1 | Uncharacterized protein. (291 aa) | ||||
ENSCCAP00000023374 | Uncharacterized protein; Belongs to the calmodulin family. (200 aa) | ||||
ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2687 aa) | ||||
CXCL10 | C-X-C motif chemokine. (96 aa) | ||||
HTT | Huntingtin. (3066 aa) | ||||
ERO1A | Endoplasmic reticulum oxidoreductase 1 alpha. (468 aa) | ||||
PTPRC | Protein tyrosine phosphatase receptor type C. (1299 aa) | ||||
BDKRB1 | Bradykinin receptor B1. (282 aa) | ||||
PRKCE | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa) | ||||
THY1 | Thy-1 cell surface antigen. (161 aa) | ||||
RYR3 | Ryanodine receptor 3. (4853 aa) | ||||
CAPN3 | Calpain 3; Belongs to the peptidase C2 family. (816 aa) | ||||
DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (314 aa) | ||||
SLC8A1 | Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (600 aa) | ||||
SELENON | EF-hand domain-containing protein. (561 aa) | ||||
CHERP | Calcium homeostasis endoplasmic reticulum protein. (927 aa) | ||||
ENSCCAP00000027698 | Uncharacterized protein; Belongs to the calmodulin family. (108 aa) | ||||
HRC | Histidine rich calcium binding protein. (642 aa) | ||||
CCL19 | C-C motif chemokine. (98 aa) | ||||
TRPA1 | Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1119 aa) | ||||
RASA3 | RAS p21 protein activator 3. (833 aa) | ||||
GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa) | ||||
CAMK2D | Calcium/calmodulin dependent protein kinase II delta. (533 aa) | ||||
METTL21C | Methyltransferase like 21C. (264 aa) | ||||
JPH2 | Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (695 aa) | ||||
TMEM38B | Transmembrane protein 38B. (291 aa) | ||||
ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (939 aa) | ||||
CALM3 | Uncharacterized protein; Belongs to the calmodulin family. (161 aa) | ||||
F2RL3 | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (385 aa) | ||||
HTR2C | 5-hydroxytryptamine receptor 2C. (458 aa) | ||||
PKD2 | Polycystin 2, transient receptor potential cation channel. (984 aa) | ||||
MTLN | Mitoregulin. (123 aa) | ||||
TRPC1 | Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (795 aa) | ||||
GSTO1 | Glutathione S-transferase omega 1. (241 aa) | ||||
DHRS7C | Dehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa) | ||||
ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa) | ||||
TPCN2 | Uncharacterized protein. (730 aa) | ||||
F2R | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa) | ||||
PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (884 aa) | ||||
TRPM2 | Transient receptor potential cation channel subfamily M member 2. (1503 aa) | ||||
NPSR1 | Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (391 aa) | ||||
CASQ1 | Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (398 aa) | ||||
CCL21 | C-C motif chemokine ligand 21. (154 aa) | ||||
CX3CL1 | C-X3-C motif chemokine ligand 1. (335 aa) | ||||
FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (281 aa) | ||||
CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2173 aa) | ||||
PDPK1 | 3-phosphoinositide dependent protein kinase 1. (562 aa) | ||||
RYR2 | Ryanodine receptor 2. (4922 aa) | ||||
TRPV1 | Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (839 aa) | ||||
CXCR3 | C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (377 aa) | ||||
ANXA6 | Annexin. (673 aa) |