STRINGSTRING
ABI1 ABI1 RARG RARG SKI SKI SH2B3 SH2B3 ENSCCAP00000021074 ENSCCAP00000021074 FGF8 FGF8 PIP4K2A PIP4K2A INSIG1 INSIG1 FGFR2 FGFR2 LEPR LEPR SLC10A7 SLC10A7 SNX10 SNX10 PTPRC PTPRC GLI3 GLI3 FGFR3 FGFR3 STC1 STC1 CDX1 CDX1 MATN1 MATN1 XYLT1 XYLT1 NPPC NPPC LTBP3 LTBP3 COL3A1 COL3A1 AMER1 AMER1 LOC108285920 LOC108285920 CHSY1 CHSY1 ATG9B ATG9B MBTPS2 MBTPS2 LRRK1 LRRK1 THBS3 THBS3 THPO THPO TGFB1 TGFB1 WNT1 WNT1 TGM2 TGM2 MAPK14 MAPK14 GPR68 GPR68 TRIP11 TRIP11 SMAD1 SMAD1 ACP5 ACP5 PHOSPHO1 PHOSPHO1 SCX SCX LEP LEP ACTN3 ACTN3 LTF LTF IMPAD1 IMPAD1 DYM DYM LOC108284754 LOC108284754 COMP COMP TMEM38B TMEM38B FOXP1 FOXP1 TP53 TP53 CYP26B1 CYP26B1 SFRP4 SFRP4 LOC108317654 LOC108317654 ITGB6 ITGB6 WASF2 WASF2 ZNF385A ZNF385A KIT KIT EXT2 EXT2 MIGA2 MIGA2 PTPN11 PTPN11 TMEM107 TMEM107 DCANP1 DCANP1 PDGFC PDGFC ADAMTS12 ADAMTS12 MEF2D MEF2D OSR2 OSR2 NAB2 NAB2 MYOC MYOC BNC2 BNC2 DDR2 DDR2 EPYC EPYC COL13A1 COL13A1 LRP5 LRP5 HOXA11 HOXA11 ATF2 ATF2 IFT172 IFT172 BMP4 BMP4 ZFPM1 ZFPM1 COL2A1 COL2A1 IHH IHH IGF1 IGF1 TFAP2A TFAP2A CCDC154 CCDC154 NSD2 NSD2 SERPINH1 SERPINH1 LOC108301643 LOC108301643 ADAMTS7 ADAMTS7 EP300 EP300 FOXN3 FOXN3 PEX7 PEX7 MSX1 MSX1 PPIB PPIB ANXA6 ANXA6 RARB RARB P3H1 P3H1 SRF SRF ENSCCAP00000039965 ENSCCAP00000039965 SCUBE2 SCUBE2 MAPK11 MAPK11 HAS2 HAS2 CHAD CHAD LRRC17 LRRC17 MCPH1 MCPH1 ENSCCAP00000018301 ENSCCAP00000018301 PITX2 PITX2 SP5 SP5 OSTN OSTN ATP6AP1 ATP6AP1 BMPR1B BMPR1B PAPPA2 PAPPA2 SHOX2 SHOX2 DSPP DSPP ECM1 ECM1 CCN4 CCN4 ENG ENG PLXNB1 PLXNB1 FGF18 FGF18 TRPV4 TRPV4 PAX1 PAX1 SMPD3 SMPD3 SULF1 SULF1 PLS3 PLS3 NPR2 NPR2 BMPR2 BMPR2 NOTUM NOTUM TTC9 TTC9 ENSCCAP00000013944 ENSCCAP00000013944 TBXT TBXT ENSCCAP00000013558 ENSCCAP00000013558 NEUROG1 NEUROG1 TGFB3 TGFB3 RPL13 RPL13 INPPL1 INPPL1 BMP6 BMP6 GLG1 GLG1 MMP16 MMP16 FAM20C FAM20C ZMPSTE24 ZMPSTE24 MMP14 MMP14 FGF4 FGF4 VPS33B VPS33B ASXL1 ASXL1 IFITM5 IFITM5 AXIN2 AXIN2 COL27A1 COL27A1 ANXA2 ANXA2 RYR1 RYR1 TGFBR2 TGFBR2 ENSCCAP00000008780 ENSCCAP00000008780 SRC SRC ENSCCAP00000008267 ENSCCAP00000008267 RARA RARA PHEX PHEX MEGF8 MEGF8 TNFSF11 TNFSF11 RANBP3L RANBP3L SULF2 SULF2 CER1 CER1 SMAD5 SMAD5 BBX BBX COL1A1 COL1A1 TULP3 TULP3 GNAS GNAS MEIS1 MEIS1 SBDS SBDS ALPL ALPL BGLAP BGLAP RAB23 RAB23 HOXB4 HOXB4 ENSCCAP00000005073 ENSCCAP00000005073 EVC EVC ATG9A ATG9A AKAP13 AKAP13 CITED2 CITED2 MPIG6B MPIG6B DHRS3 DHRS3 FREM1 FREM1 MEF2C MEF2C SH3PXD2B SH3PXD2B BGN BGN DLX5 DLX5 SPNS2 SPNS2 CTC1 CTC1 BMP2 BMP2 SLC38A10 SLC38A10 FLI1 FLI1 PAPSS2 PAPSS2 RIPPLY2 RIPPLY2 SOX9 SOX9 TRIM45 TRIM45 SEMA4D SEMA4D PTPN6 PTPN6 LOC108298339 LOC108298339 MED1 MED1 RUNX2 RUNX2 EXT1 EXT1 NAB1 NAB1 MMP13 MMP13 ZBTB16 ZBTB16 ENSCCAP00000018427 ENSCCAP00000018427 EBP EBP FLNA FLNA MAP2K6 MAP2K6 LOC108304701 LOC108304701 LOC108298696 LOC108298696
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABI1Abl interactor 1. (508 aa)
RARGRetinoic acid receptor gamma. (456 aa)
SKISKI proto-oncogene. (729 aa)
SH2B3SH2B adaptor protein 3. (576 aa)
ENSCCAP00000021074Uncharacterized protein. (313 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (406 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
FGFR2Fibroblast growth factor receptor. (782 aa)
LEPRLeptin receptor. (1165 aa)
SLC10A7Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (358 aa)
SNX10Sorting nexin 10. (201 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1299 aa)
GLI3GLI family zinc finger 3. (1577 aa)
FGFR3Fibroblast growth factor receptor. (808 aa)
STC1Stanniocalcin 1. (248 aa)
CDX1Caudal type homeobox 1. (265 aa)
MATN1Matrilin 1. (496 aa)
XYLT1Xylosyltransferase 1. (957 aa)
NPPCNatriuretic peptide C. (127 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1300 aa)
COL3A1Collagen type III alpha 1 chain. (1465 aa)
AMER1APC membrane recruitment protein 1. (804 aa)
LOC108285920Uncharacterized protein. (248 aa)
CHSY1Hexosyltransferase. (802 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (921 aa)
MBTPS2Membrane bound transcription factor peptidase, site 2. (446 aa)
LRRK1Leucine rich repeat kinase 1. (2014 aa)
THBS3Thrombospondin 3. (956 aa)
THPOThrombopoietin. (335 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (314 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
TGM2Transglutaminase 2. (687 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (370 aa)
TRIP11Thyroid hormone receptor interactor 11. (1978 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (267 aa)
SCXScleraxis bHLH transcription factor. (203 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (936 aa)
LTFLactotransferrin; Belongs to the transferrin family. (713 aa)
IMPAD1Inositol monophosphatase domain containing 1. (359 aa)
DYMDymeclin. (669 aa)
LOC108284754Annexin. (339 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
TMEM38BTransmembrane protein 38B. (291 aa)
FOXP1Forkhead box P1. (693 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (395 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
SFRP4Secreted frizzled related protein 4. (368 aa)
LOC108317654Pep_M12B_propep domain-containing protein. (177 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
WASF2WASP family member 2. (498 aa)
ZNF385AZinc finger protein 385A. (414 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (740 aa)
MIGA2Mitoguardin 2. (593 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
TMEM107Transmembrane protein 107. (140 aa)
DCANP1Dendritic cell associated nuclear protein. (175 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif 12. (1620 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
OSR2Odd-skipped related transciption factor 2. (417 aa)
NAB2NGFI-A binding protein 2. (525 aa)
MYOCMyocilin. (504 aa)
BNC2Basonuclin 2. (1099 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
EPYCEpiphycan. (319 aa)
COL13A1Collagen type XIII alpha 1 chain. (717 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1603 aa)
HOXA11Homeobox A11. (313 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
IFT172Uncharacterized protein. (1602 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
ZFPM1Zinc finger protein, FOG family member 1. (1001 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
IGF1Insulin like growth factor 1. (199 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
CCDC154Coiled-coil domain containing 154. (672 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1369 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (418 aa)
LOC108301643Uncharacterized protein. (400 aa)
ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif 7. (1685 aa)
EP300E1A binding protein p300. (2420 aa)
FOXN3Forkhead box N3. (490 aa)
PEX7Peroxisomal biogenesis factor 7. (323 aa)
MSX1Msh homeobox 1. (303 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
ANXA6Annexin. (673 aa)
RARBRetinoic acid receptor beta. (448 aa)
P3H1Prolyl 3-hydroxylase 1. (758 aa)
SRFSerum response factor. (509 aa)
ENSCCAP00000039965Uncharacterized protein. (374 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (997 aa)
MAPK11Mitogen-activated protein kinase. (368 aa)
HAS2Hyaluronan synthase 2. (552 aa)
CHADChondroadherin. (359 aa)
LRRC17Leucine rich repeat containing 17. (441 aa)
MCPH1Microcephalin 1. (841 aa)
ENSCCAP00000018301Uncharacterized protein. (279 aa)
PITX2Homeobox protein. (325 aa)
SP5Sp5 transcription factor. (398 aa)
OSTNOsteocrin. (133 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (468 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
PAPPA2Pappalysin 2. (1790 aa)
SHOX2Short stature homeobox 2. (351 aa)
DSPPDentin sialophosphoprotein. (1029 aa)
ECM1Extracellular matrix protein 1. (565 aa)
CCN4Cellular communication network factor 4. (367 aa)
ENGEndoglin. (655 aa)
PLXNB1Plexin B1. (2137 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
PAX1Paired box 1. (513 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (872 aa)
PLS3Plastin 3. (633 aa)
NPR2Guanylate cyclase. (1047 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (961 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (503 aa)
TTC9Tetratricopeptide repeat domain 9. (222 aa)
ENSCCAP00000013944Uncharacterized protein. (340 aa)
TBXTT-box transcription factor T. (434 aa)
ENSCCAP00000013558Uncharacterized protein. (296 aa)
NEUROG1Neurogenin 1. (239 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
RPL1360S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. (211 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1263 aa)
BMP6Bone morphogenetic protein 6. (508 aa)
GLG1Golgi glycoprotein 1. (1224 aa)
MMP16Matrix metallopeptidase 16. (607 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (584 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (479 aa)
MMP14Matrix metallopeptidase 14. (592 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
VPS33BUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (595 aa)
ASXL1ASXL transcriptional regulator 1. (1541 aa)
IFITM5Interferon induced transmembrane protein 5. (132 aa)
AXIN2Axin 2. (842 aa)
COL27A1Collagen type XXVII alpha 1 chain. (1822 aa)
ANXA2Annexin. (357 aa)
RYR1Ryanodine receptor 1. (4990 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
ENSCCAP00000008780Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)
SRCTyrosine-protein kinase. (542 aa)
ENSCCAP00000008267GRIP domain-containing protein. (1887 aa)
RARARetinoic acid receptor alpha. (464 aa)
PHEXPhosphate regulating endopeptidase homolog X-linked. (749 aa)
MEGF8Multiple EGF like domains 8. (2855 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
RANBP3LRAN binding protein 3 like. (488 aa)
SULF2Sulfatase 2. (803 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
BBXBBX high mobility group box domain containing. (941 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (395 aa)
GNASGNAS complex locus. (1044 aa)
MEIS1Meis homeobox 1. (463 aa)
SBDSSBDS ribosome maturation factor. (250 aa)
ALPLAlkaline phosphatase. (524 aa)
BGLAPOsteocalcin; Binds strongly to apatite and calcium. (100 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
HOXB4Homeobox B4. (245 aa)
ENSCCAP00000005073Uncharacterized protein. (94 aa)
EVCEvC ciliary complex subunit 1. (990 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (839 aa)
AKAP13A-kinase anchoring protein 13. (2834 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (275 aa)
MPIG6BMegakaryocyte and platelet inhibitory receptor G6b. (237 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
FREM1FRAS1 related extracellular matrix 1. (2181 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
SH3PXD2BSH3 and PX domains 2B. (909 aa)
BGNBiglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (369 aa)
DLX5Distal-less homeobox 5. (289 aa)
SPNS2Sphingolipid transporter 2. (549 aa)
CTC1CST telomere replication complex component 1. (1162 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
SLC38A10Solute carrier family 38 member 10. (1122 aa)
FLI1Fli-1 proto-oncogene, ETS transcription factor. (452 aa)
PAPSS23'-phosphoadenosine 5'-phosphosulfate synthase 2. (614 aa)
RIPPLY2Ripply transcriptional repressor 2. (128 aa)
SOX9SRY-box transcription factor 9. (509 aa)
TRIM45Tripartite motif containing 45. (580 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
LOC108298339Uncharacterized protein. (164 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1517 aa)
RUNX2RUNX family transcription factor 2. (540 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
NAB1NGFI-A binding protein 1. (487 aa)
MMP13Matrix metallopeptidase 13. (489 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
ENSCCAP00000018427SH2 domain-containing protein. (239 aa)
EBPEXPERA domain-containing protein. (230 aa)
FLNAFilamin A. (2192 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
LOC108304701WD_REPEATS_REGION domain-containing protein. (630 aa)
LOC108298696Uncharacterized protein. (349 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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