(18 nodes) Morphogenesis of an epithelial fold network (Cebus capucinus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMP7	Bone morphogenetic protein 7. (430 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	SOSTDC1	Sclerostin domain containing 1. (230 aa)
	OVOL2	Ovo like zinc finger 2. (275 aa)
	HOXD13	Homeobox D13. (345 aa)
	GDF7	Growth differentiation factor 7. (455 aa)
	CECR2	CECR2 histone acetyl-lysine reader. (1431 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	RDH10	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
	NODAL	Nodal growth differentiation factor. (347 aa)
	LOC108293547	Uncharacterized protein. (773 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
	LUZP1	Leucine zipper protein 1. (1074 aa)
	FGFR2	Fibroblast growth factor receptor. (782 aa)
	HIF1A	Uncharacterized protein. (848 aa)
	TP63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
	BMP5	Bone morphogenetic protein 5. (454 aa)
	AR	Androgen receptor. (887 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	BMP5	ENSCCAP00000036602	ENSCCAP00000012928	Bone morphogenetic protein 4.	Bone morphogenetic protein 5.	0.613
BMP4	BMP7	ENSCCAP00000036602	ENSCCAP00000008930	Bone morphogenetic protein 4.	Bone morphogenetic protein 7.	0.809
BMP4	FGF10	ENSCCAP00000036602	ENSCCAP00000025026	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.520
BMP4	FGFR2	ENSCCAP00000036602	ENSCCAP00000022112	Bone morphogenetic protein 4.	Fibroblast growth factor receptor.	0.454
BMP4	NOG	ENSCCAP00000036602	ENSCCAP00000005156	Bone morphogenetic protein 4.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.997
BMP5	BMP4	ENSCCAP00000012928	ENSCCAP00000036602	Bone morphogenetic protein 5.	Bone morphogenetic protein 4.	0.613
BMP5	GDF7	ENSCCAP00000012928	ENSCCAP00000035218	Bone morphogenetic protein 5.	Growth differentiation factor 7.	0.729
BMP5	NOG	ENSCCAP00000012928	ENSCCAP00000005156	Bone morphogenetic protein 5.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.991
BMP7	BMP4	ENSCCAP00000008930	ENSCCAP00000036602	Bone morphogenetic protein 7.	Bone morphogenetic protein 4.	0.809
BMP7	FGFR2	ENSCCAP00000008930	ENSCCAP00000022112	Bone morphogenetic protein 7.	Fibroblast growth factor receptor.	0.634
BMP7	GDF7	ENSCCAP00000008930	ENSCCAP00000035218	Bone morphogenetic protein 7.	Growth differentiation factor 7.	0.752
BMP7	NOG	ENSCCAP00000008930	ENSCCAP00000005156	Bone morphogenetic protein 7.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.996
FGF10	BMP4	ENSCCAP00000025026	ENSCCAP00000036602	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.520
FGF10	FGFR2	ENSCCAP00000025026	ENSCCAP00000022112	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.989
FGFR2	BMP4	ENSCCAP00000022112	ENSCCAP00000036602	Fibroblast growth factor receptor.	Bone morphogenetic protein 4.	0.454
FGFR2	BMP7	ENSCCAP00000022112	ENSCCAP00000008930	Fibroblast growth factor receptor.	Bone morphogenetic protein 7.	0.634
FGFR2	FGF10	ENSCCAP00000022112	ENSCCAP00000025026	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.989
GDF7	BMP5	ENSCCAP00000035218	ENSCCAP00000012928	Growth differentiation factor 7.	Bone morphogenetic protein 5.	0.729
GDF7	BMP7	ENSCCAP00000035218	ENSCCAP00000008930	Growth differentiation factor 7.	Bone morphogenetic protein 7.	0.752
GDF7	NOG	ENSCCAP00000035218	ENSCCAP00000005156	Growth differentiation factor 7.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.916