STRINGSTRING
LOC108318597 LOC108318597 SPTLC2 SPTLC2 ENSCCAP00000005305 ENSCCAP00000005305 ARID5B ARID5B DYRK1B DYRK1B RORC RORC SOX8 SOX8 SLC25A25 SLC25A25 PPARGC1A PPARGC1A BBS4 BBS4 HMGA2 HMGA2 DGAT2 DGAT2 ZNF516 ZNF516 CSF1 CSF1 PIK3CA PIK3CA SELENOM SELENOM UMODL1 UMODL1 LOC108304334 LOC108304334 XBP1 XBP1 LOC108312451 LOC108312451 CASR CASR AMER1 AMER1 HRAS HRAS TBL1XR1 TBL1XR1 LEP LEP ARRDC3 ARRDC3 LOC108313247 LOC108313247 ENSCCAP00000038982 ENSCCAP00000038982 PUM2 PUM2 ATF2 ATF2 LRP5 LRP5 ENSCCAP00000034806 ENSCCAP00000034806 PGRMC2 PGRMC2 SPART SPART PPARD PPARD RASAL2 RASAL2 ENSCCAP00000031460 ENSCCAP00000031460 HMGCS2 HMGCS2 ENSCCAP00000030012 ENSCCAP00000030012 VPS13B VPS13B PAXIP1 PAXIP1 CDK4 CDK4 DHRS7B DHRS7B SH3PXD2B SH3PXD2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108318597IPT/TIG domain-containing protein. (405 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (560 aa)
ENSCCAP00000005305Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (220 aa)
ARID5BAT-rich interaction domain 5B. (1188 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (629 aa)
RORCRAR related orphan receptor C. (522 aa)
SOX8SRY-box transcription factor 8. (446 aa)
SLC25A25Solute carrier family 25 member 25; Belongs to the mitochondrial carrier (TC 2.A.29) family. (502 aa)
PPARGC1APPARG coactivator 1 alpha. (812 aa)
BBS4Bardet-Biedl syndrome 4. (494 aa)
HMGA2Uncharacterized protein. (118 aa)
DGAT2Diacylglycerol O-acyltransferase 2. (382 aa)
ZNF516Zinc finger protein 516. (1168 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (551 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SELENOMSelenoprotein M. (144 aa)
UMODL1Uromodulin like 1. (1443 aa)
LOC108304334Protein kinase domain-containing protein. (342 aa)
XBP1BZIP domain-containing protein. (375 aa)
LOC108312451COE1_DBD domain-containing protein. (184 aa)
CASRCalcium sensing receptor. (1077 aa)
AMER1APC membrane recruitment protein 1. (804 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (514 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
ARRDC3Arrestin domain containing 3. (414 aa)
LOC108313247Protein kinase domain-containing protein. (276 aa)
ENSCCAP00000038982Uncharacterized protein. (128 aa)
PUM2Pumilio RNA binding family member 2. (1065 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1603 aa)
ENSCCAP00000034806Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (260 aa)
PGRMC2Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family. (223 aa)
SPARTSpartin. (660 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
RASAL2RAS protein activator like 2. (1256 aa)
ENSCCAP00000031460Protein kinase domain-containing protein. (272 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (466 aa)
ENSCCAP00000030012Protein kinase domain-containing protein. (266 aa)
VPS13BVacuolar protein sorting 13 homolog B. (3902 aa)
PAXIP1PAX interacting protein 1. (1064 aa)
CDK4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
DHRS7BDehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa)
SH3PXD2BSH3 and PX domains 2B. (909 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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