(19 nodes) Labyrinthine layer morphogenesis network (Cebus capucinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ZFP36L1	ZFP36 ring finger protein like 1. (338 aa)
	SOCS3	Suppressor of cytokine signaling 3. (225 aa)
	FZD5	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
	TMED2	Transmembrane p24 trafficking protein 2. (208 aa)
	ADM	Adrenomedullin. (184 aa)
	BMP7	Bone morphogenetic protein 7. (430 aa)
	CCN1	Cellular communication network factor 1. (381 aa)
	GRHL2	Grainyhead like transcription factor 2. (625 aa)
	LEF1	Lymphoid enhancer binding factor 1. (399 aa)
	NCOA1	Nuclear receptor coactivator. (1441 aa)
	BMP5	Bone morphogenetic protein 5. (454 aa)
	ST14	Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa)
	FGFR2	Fibroblast growth factor receptor. (782 aa)
	RSPO3	R-spondin 3. (292 aa)
	GRB2	Growth factor receptor bound protein 2. (217 aa)
	GCM1	Glial cells missing transcription factor 1. (436 aa)
	IL10	Interleukin 10. (178 aa)
	SPINT1	Serine peptidase inhibitor, Kunitz type 1. (531 aa)
	WNT7B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP7	FGFR2	ENSCCAP00000008930	ENSCCAP00000022112	Bone morphogenetic protein 7.	Fibroblast growth factor receptor.	0.634
FGFR2	BMP7	ENSCCAP00000022112	ENSCCAP00000008930	Fibroblast growth factor receptor.	Bone morphogenetic protein 7.	0.634
FGFR2	GRB2	ENSCCAP00000022112	ENSCCAP00000027991	Fibroblast growth factor receptor.	Growth factor receptor bound protein 2.	0.914
FZD5	WNT7B	ENSCCAP00000001779	ENSCCAP00000037271	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.877
GRB2	FGFR2	ENSCCAP00000027991	ENSCCAP00000022112	Growth factor receptor bound protein 2.	Fibroblast growth factor receptor.	0.914
IL10	SOCS3	ENSCCAP00000034893	ENSCCAP00000001406	Interleukin 10.	Suppressor of cytokine signaling 3.	0.552
SOCS3	IL10	ENSCCAP00000001406	ENSCCAP00000034893	Suppressor of cytokine signaling 3.	Interleukin 10.	0.552
SPINT1	ST14	ENSCCAP00000035840	ENSCCAP00000020909	Serine peptidase inhibitor, Kunitz type 1.	Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family.	0.970
ST14	SPINT1	ENSCCAP00000020909	ENSCCAP00000035840	Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family.	Serine peptidase inhibitor, Kunitz type 1.	0.970
WNT7B	FZD5	ENSCCAP00000037271	ENSCCAP00000001779	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.	0.877