STRINGSTRING
IMPAD1 IMPAD1 TGFBI TGFBI GPLD1 GPLD1 PKD1 PKD1 ITGB8 ITGB8 SCUBE2 SCUBE2 SRF SRF EGR1 EGR1 RARB RARB ANXA6 ANXA6 ARRDC3 ARRDC3 WNT10B WNT10B LOC108313247 LOC108313247 ENSCCAP00000038982 ENSCCAP00000038982 MSX1 MSX1 PUM2 PUM2 FOXA1 FOXA1 HAND1 HAND1 ADAMTS7 ADAMTS7 SERPINH1 SERPINH1 MAPK3 MAPK3 WNT7B WNT7B IHH IHH COL2A1 COL2A1 BMP4 BMP4 HYAL1 HYAL1 ATF2 ATF2 HOXA11 HOXA11 ZBTB16 ZBTB16 MMP13 MMP13 EXT1 EXT1 RUNX2 RUNX2 FOXD1 FOXD1 NFIB NFIB SOX9 SOX9 HYAL2 HYAL2 HOXB3 HOXB3 GPR4 GPR4 LOC108288808 LOC108288808 TWSG1 TWSG1 DHRS7B DHRS7B BMP2 BMP2 LOC108318597 LOC108318597 UNCX UNCX ATP7A ATP7A LOC108294705 LOC108294705 BGN BGN SH3PXD2B SH3PXD2B RSPO2 RSPO2 MEF2C MEF2C PRRX1 PRRX1 RB1 RB1 SOX5 SOX5 EVC EVC ENSCCAP00000005073 ENSCCAP00000005073 NOG NOG EDN1 EDN1 SPTLC2 SPTLC2 ENSCCAP00000005305 ENSCCAP00000005305 ESRRA ESRRA ACAN ACAN HYAL3 HYAL3 ARID5B ARID5B LRP5 LRP5 BMP1 BMP1 TYMS TYMS GDF5 GDF5 EPYC EPYC ENSCCAP00000034806 ENSCCAP00000034806 PGRMC2 PGRMC2 COL5A1 COL5A1 ENSCCAP00000034412 ENSCCAP00000034412 TAPT1 TAPT1 COL11A1 COL11A1 OSR2 OSR2 SOX6 SOX6 BMPR1A BMPR1A NOTCH1 NOTCH1 THRA THRA MEF2D MEF2D CCN2 CCN2 MUSTN1 MUSTN1 SLC39A13 SLC39A13 SPART SPART ADAMTS12 ADAMTS12 PPARD PPARD MEX3C MEX3C LOX LOX RASAL2 RASAL2 BMP3 BMP3 ENSCCAP00000031460 ENSCCAP00000031460 EXT2 EXT2 BBS2 BBS2 HMGCS2 HMGCS2 LOC108317654 LOC108317654 FGF6 FGF6 MATN3 MATN3 ENSCCAP00000030012 ENSCCAP00000030012 VPS13B VPS13B CNMD CNMD RUNX3 RUNX3 BBS1 BBS1 COL1A1 COL1A1 HOXD3 HOXD3 PAXIP1 PAXIP1 FOXC2 FOXC2 COMP COMP PBXIP1 PBXIP1 DDRGK1 DDRGK1 SMAD5 SMAD5 CER1 CER1 COL11A2 COL11A2 SNORC SNORC SIX2 SIX2 SULF2 SULF2 FGF9 FGF9 RARA RARA ENSCCAP00000008267 ENSCCAP00000008267 ENSCCAP00000008780 ENSCCAP00000008780 BMP7 BMP7 GHRL GHRL CCN1 CCN1 DYRK1B DYRK1B TGFBR2 TGFBR2 COL27A1 COL27A1 CHRDL2 CHRDL2 AXIN2 AXIN2 SLC39A14 SLC39A14 RORC RORC HOXA3 HOXA3 FGF4 FGF4 DLX2 DLX2 ZMPSTE24 ZMPSTE24 SNAI2 SNAI2 BMP5 BMP5 BMP6 BMP6 SOX8 SOX8 SLC25A25 SLC25A25 PPARGC1A PPARGC1A GDF2 GDF2 BBS4 BBS4 CHST11 CHST11 BMPR2 BMPR2 HMGA2 HMGA2 CD34 CD34 WNT5B WNT5B SULF1 SULF1 SMPD3 SMPD3 SNX19 SNX19 CTNNB1 CTNNB1 PTH1R PTH1R TRPV4 TRPV4 FGF18 FGF18 DGAT2 DGAT2 MKKS MKKS CREB3L2 CREB3L2 ECM1 ECM1 DSPP DSPP SHOX2 SHOX2 ID4 ID4 BMPR1B BMPR1B WNT5A WNT5A PITX1 PITX1 HES5 HES5 BARX2 BARX2 LOC108304701 LOC108304701 SFRP2 SFRP2 ZNF516 ZNF516 RARG RARG HAND2 HAND2 CD44 CD44 CSF1 CSF1 PIK3CA PIK3CA SATB2 SATB2 SELENOM SELENOM UMODL1 UMODL1 HIF1A HIF1A LOC108304334 LOC108304334 XBP1 XBP1 MYF5 MYF5 OSR1 OSR1 HOXA5 HOXA5 SNAI1 SNAI1 LOC108312451 LOC108312451 GLI3 GLI3 FGFR3 FGFR3 STC1 STC1 MATN1 MATN1 CASR CASR NPPC NPPC LTBP3 LTBP3 COL3A1 COL3A1 AMER1 AMER1 EIF2AK3 EIF2AK3 LOC108285920 LOC108285920 CHSY1 CHSY1 CRIP1 CRIP1 OTOR OTOR WNT2B WNT2B PDGFB PDGFB THBS3 THBS3 HOXC4 HOXC4 CYTL1 CYTL1 ZEB1 ZEB1 ARID5A ARID5A TGFB1 TGFB1 MAPK14 MAPK14 WNT7A WNT7A HRAS HRAS PDGFRB PDGFRB LOC108293547 LOC108293547 TRIP11 TRIP11 SMAD1 SMAD1 SCX SCX TBL1XR1 TBL1XR1 CCN3 CCN3 LEP LEP CDK4 CDK4 RUNX1 RUNX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IMPAD1Inositol monophosphatase domain containing 1. (359 aa)
TGFBITransforming growth factor beta induced. (679 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (840 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4246 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (770 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (997 aa)
SRFSerum response factor. (509 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa)
RARBRetinoic acid receptor beta. (448 aa)
ANXA6Annexin. (673 aa)
ARRDC3Arrestin domain containing 3. (414 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
LOC108313247Protein kinase domain-containing protein. (276 aa)
ENSCCAP00000038982Uncharacterized protein. (128 aa)
MSX1Msh homeobox 1. (303 aa)
PUM2Pumilio RNA binding family member 2. (1065 aa)
FOXA1Forkhead box A1. (470 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif 7. (1685 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (418 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
HYAL1Hyaluronidase. (435 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
HOXA11Homeobox A11. (313 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
MMP13Matrix metallopeptidase 13. (489 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
RUNX2RUNX family transcription factor 2. (540 aa)
FOXD1Forkhead box D1. (468 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
SOX9SRY-box transcription factor 9. (509 aa)
HYAL2Hyaluronidase. (474 aa)
HOXB3Homeobox B3. (434 aa)
GPR4G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (362 aa)
LOC108288808TGF_BETA_2 domain-containing protein. (365 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
DHRS7BDehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
LOC108318597IPT/TIG domain-containing protein. (405 aa)
UNCXUNC homeobox. (530 aa)
ATP7AATPase copper transporting alpha. (1476 aa)
LOC108294705Thymidylat_synt domain-containing protein. (302 aa)
BGNBiglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (369 aa)
SH3PXD2BSH3 and PX domains 2B. (909 aa)
RSPO2R-spondin 2. (243 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
PRRX1Paired related homeobox 1. (245 aa)
RB1RB transcriptional corepressor 1. (927 aa)
SOX5SRY-box transcription factor 5. (763 aa)
EVCEvC ciliary complex subunit 1. (990 aa)
ENSCCAP00000005073Uncharacterized protein. (94 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
EDN1Endothelin 1. (212 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (560 aa)
ENSCCAP00000005305Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (220 aa)
ESRRAEstrogen related receptor alpha. (421 aa)
ACANAggrecan. (2151 aa)
HYAL3Hyaluronidase. (415 aa)
ARID5BAT-rich interaction domain 5B. (1188 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1603 aa)
BMP1Metalloendopeptidase. (987 aa)
TYMSThymidylat_synt domain-containing protein. (313 aa)
GDF5Growth differentiation factor 5. (501 aa)
EPYCEpiphycan. (319 aa)
ENSCCAP00000034806Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (260 aa)
PGRMC2Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family. (223 aa)
COL5A1Collagen type V alpha 1 chain. (1840 aa)
ENSCCAP00000034412TGF_BETA_2 domain-containing protein. (341 aa)
TAPT1Transmembrane anterior posterior transformation 1. (567 aa)
COL11A1Collagen type XI alpha 1 chain. (1817 aa)
OSR2Odd-skipped related transciption factor 2. (417 aa)
SOX6SRY-box transcription factor 6. (829 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (432 aa)
NOTCH1Notch receptor 1. (2550 aa)
THRAThyroid hormone receptor alpha. (490 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
CCN2Cellular communication network factor 2. (349 aa)
MUSTN1Uncharacterized protein. (87 aa)
SLC39A13Solute carrier family 39 member 13. (368 aa)
SPARTSpartin. (660 aa)
ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif 12. (1620 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
MEX3CMex-3 RNA binding family member C. (660 aa)
LOXLysyl oxidase. (417 aa)
RASAL2RAS protein activator like 2. (1256 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (472 aa)
ENSCCAP00000031460Protein kinase domain-containing protein. (272 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (740 aa)
BBS2Bardet-Biedl syndrome 2. (614 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (466 aa)
LOC108317654Pep_M12B_propep domain-containing protein. (177 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
MATN3Matrilin 3. (487 aa)
ENSCCAP00000030012Protein kinase domain-containing protein. (266 aa)
VPS13BVacuolar protein sorting 13 homolog B. (3902 aa)
CNMDChondromodulin. (334 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (430 aa)
BBS1BBS1 domain-containing protein. (593 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
HOXD3Homeobox D3. (432 aa)
PAXIP1PAX interacting protein 1. (1064 aa)
FOXC2Forkhead box C2. (501 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
PBXIP1PBX homeobox interacting protein 1. (730 aa)
DDRGK1DDRGK domain containing 1. (315 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
COL11A2Collagen type XI alpha 2 chain. (1737 aa)
SNORCSecondary ossification center associated regulator of chondrocyte maturation. (121 aa)
SIX2SIX homeobox 2. (291 aa)
SULF2Sulfatase 2. (803 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
RARARetinoic acid receptor alpha. (464 aa)
ENSCCAP00000008267GRIP domain-containing protein. (1887 aa)
ENSCCAP00000008780Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)
BMP7Bone morphogenetic protein 7. (430 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
CCN1Cellular communication network factor 1. (381 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (629 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
COL27A1Collagen type XXVII alpha 1 chain. (1822 aa)
CHRDL2Chordin like 2. (430 aa)
AXIN2Axin 2. (842 aa)
SLC39A14Solute carrier family 39 member 14. (490 aa)
RORCRAR related orphan receptor C. (522 aa)
HOXA3Homeobox A3. (444 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
DLX2Distal-less homeobox 2. (328 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (479 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
BMP6Bone morphogenetic protein 6. (508 aa)
SOX8SRY-box transcription factor 8. (446 aa)
SLC25A25Solute carrier family 25 member 25; Belongs to the mitochondrial carrier (TC 2.A.29) family. (502 aa)
PPARGC1APPARG coactivator 1 alpha. (812 aa)
GDF2Growth differentiation factor 2. (429 aa)
BBS4Bardet-Biedl syndrome 4. (494 aa)
CHST11Carbohydrate sulfotransferase. (352 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (961 aa)
HMGA2Uncharacterized protein. (118 aa)
CD34CD34 molecule. (386 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (872 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
SNX19Sorting nexin 19. (993 aa)
CTNNB1Catenin beta 1. (781 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (593 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
DGAT2Diacylglycerol O-acyltransferase 2. (382 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
ECM1Extracellular matrix protein 1. (565 aa)
DSPPDentin sialophosphoprotein. (1029 aa)
SHOX2Short stature homeobox 2. (351 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (161 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
PITX1Homeobox protein. (314 aa)
HES5Hes family bHLH transcription factor 5. (162 aa)
BARX2BARX homeobox 2. (279 aa)
LOC108304701WD_REPEATS_REGION domain-containing protein. (630 aa)
SFRP2Secreted frizzled related protein 2. (296 aa)
ZNF516Zinc finger protein 516. (1168 aa)
RARGRetinoic acid receptor gamma. (456 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
CD44CD44 molecule (Indian blood group). (734 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (551 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SATB2DNA-binding protein SATB. (733 aa)
SELENOMSelenoprotein M. (144 aa)
UMODL1Uromodulin like 1. (1443 aa)
HIF1AUncharacterized protein. (848 aa)
LOC108304334Protein kinase domain-containing protein. (342 aa)
XBP1BZIP domain-containing protein. (375 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
HOXA5Homeobox A5. (270 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
LOC108312451COE1_DBD domain-containing protein. (184 aa)
GLI3GLI family zinc finger 3. (1577 aa)
FGFR3Fibroblast growth factor receptor. (808 aa)
STC1Stanniocalcin 1. (248 aa)
MATN1Matrilin 1. (496 aa)
CASRCalcium sensing receptor. (1077 aa)
NPPCNatriuretic peptide C. (127 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1300 aa)
COL3A1Collagen type III alpha 1 chain. (1465 aa)
AMER1APC membrane recruitment protein 1. (804 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1114 aa)
LOC108285920Uncharacterized protein. (248 aa)
CHSY1Hexosyltransferase. (802 aa)
CRIP1LIM zinc-binding domain-containing protein. (77 aa)
OTOROtoraplin. (125 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
THBS3Thrombospondin 3. (956 aa)
HOXC4Homeobox C4. (264 aa)
CYTL1Cytokine like 1. (136 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1124 aa)
ARID5AAT-rich interaction domain 5A. (594 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (314 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1108 aa)
LOC108293547Uncharacterized protein. (773 aa)
TRIP11Thyroid hormone receptor interactor 11. (1978 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
SCXScleraxis bHLH transcription factor. (203 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (514 aa)
CCN3Cellular communication network factor 3. (357 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
CDK4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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