83 items (Cebus capucinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TRIP13	Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (413 aa)
	MEIOC	Meiosis specific with coiled-coil domain. (953 aa)
	FANCD2	FA complementation group D2. (1442 aa)
	P3H4	Prolyl 3-hydroxylase family member 4 (non-enzymatic). (437 aa)
	NCAPD2	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1401 aa)
	ZCWPW1	Zinc finger CW-type and PWWP domain containing 1. (620 aa)
	RNF212	Ring finger protein 212. (253 aa)
	STAG1	Stromal antigen 1. (1267 aa)
	EHMT2	Euchromatic histone lysine methyltransferase 2. (1268 aa)
	LOC108303214	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1149 aa)
	ENSCCAP00000034559	Mnd1 domain-containing protein. (127 aa)
	SYCE3	Synaptonemal complex central element protein 3. (88 aa)
	RAD21	RAD21 cohesin complex component. (605 aa)
	SIRT7	Sirtuin 7. (421 aa)
	PSMC3IP	PSMC3 interacting protein. (217 aa)
	MAJIN	Membrane anchored junction protein. (214 aa)
	MSH4	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (870 aa)
	NCAPH	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (741 aa)
	SMC2	Structural maintenance of chromosomes protein. (1182 aa)
	SYCP1	Synaptonemal complex protein 1. (976 aa)
	BAG6	BCL2 associated athanogene 6. (1146 aa)
	MSH5	DNA_MISMATCH_REPAIR_2 domain-containing protein. (833 aa)
	SYCE2	Synaptonemal complex central element protein 2. (178 aa)
	ENSCCAP00000031489	HTH myb-type domain-containing protein. (287 aa)
	SMC1A	Structural maintenance of chromosomes protein. (1233 aa)
	C14orf39	Chromosome 14 open reading frame 39. (587 aa)
	TEX11	Uncharacterized protein. (494 aa)
	BUB1	BUB1 mitotic checkpoint serine/threonine kinase. (1066 aa)
	MND1	Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (207 aa)
	MAEL	Maelstrom spermatogenic transposon silencer. (434 aa)
	RAD51C	RECA_2 domain-containing protein. (352 aa)
	C1orf146	Chromosome 1 open reading frame 146. (180 aa)
	ENSCCAP00000029615	Mnd1 domain-containing protein. (155 aa)
	SGO2	Shugoshin 2. (1259 aa)
	ENSCCAP00000028238	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (422 aa)
	LOC108306685	Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (188 aa)
	TERB2	Telomere repeat binding bouquet formation protein 2. (221 aa)
	TEX15	Testis expressed 15, meiosis and synapsis associated. (3175 aa)
	CCDC36	Coiled-coil domain containing 36. (600 aa)
	ENSCCAP00000024677	RING-type domain-containing protein. (259 aa)
	CCDC155	Coiled-coil domain containing 155. (560 aa)
	MLH3	MutL homolog 3. (1456 aa)
	ATM	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3000 aa)
	HORMAD2	HORMA domain containing 2. (307 aa)
	HORMAD1	HORMA domain containing 1. (319 aa)
	SYCE1	Synaptonemal complex central element protein 1. (333 aa)
	SYCE1L	Synaptonemal complex central element protein 1 like. (188 aa)
	MEIKIN	Meiotic kinetochore factor. (346 aa)
	BUB1B	BUB1 N-terminal domain-containing protein. (1039 aa)
	MEI4	Meiotic double-stranded break formation protein 4. (384 aa)
	ANKRD31	Ankyrin repeat domain 31. (1929 aa)
	ATRX	ATRX chromatin remodeler. (2240 aa)
	ENSCCAP00000015138	TRF domain-containing protein. (250 aa)
	PPP2R1A	Protein phosphatase 2 scaffold subunit Aalpha. (589 aa)
	TEX12	Testis expressed 12. (123 aa)
	MEIOB	Meiosis specific with OB-fold. (455 aa)
	BRIP1	BRCA1 interacting protein C-terminal helicase 1. (1212 aa)
	CCNB1IP1	RING-type domain-containing protein. (277 aa)
	NCAPD3	Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1498 aa)
	LOC108317875	RECA_2 domain-containing protein. (351 aa)
	TERB1	Telomere repeat binding bouquet formation protein 1. (695 aa)
	REC8	REC8 meiotic recombination protein. (548 aa)
	SGO1	Shugoshin 1. (522 aa)
	RNF212B	Ring finger protein 212B. (275 aa)
	SMC4	Structural maintenance of chromosomes protein. (1287 aa)
	TERF1	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (376 aa)
	SPO11	SPO11 initiator of meiotic double stranded breaks. (396 aa)
	ENSCCAP00000009590	Rad21_Rec8 domain-containing protein. (546 aa)
	RAD51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
	DMC1	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (311 aa)
	LOC108297589	Uncharacterized protein. (430 aa)
	SUN1	Sad1 and UNC84 domain containing 1. (813 aa)
	NDC1	NDC1 transmembrane nucleoporin. (776 aa)
	STAG3	Stromal antigen 3. (1247 aa)
	CCNE2	Cyclin E2; Belongs to the cyclin family. (404 aa)
	CCNE1	Cyclin E1; Belongs to the cyclin family. (410 aa)
	MLH1	MutL homolog 1. (757 aa)
	SPATA22	Spermatogenesis associated 22. (363 aa)
	SYCP2	Synaptonemal complex protein 2. (1511 aa)
	STAG2	Stromal antigen 2. (1242 aa)
	NCAPH2	Non-SMC condensin II complex subunit H2. (570 aa)
	AGO4	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (861 aa)
	ENSCCAP00000000393	Uncharacterized protein. (145 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD31	CCDC36	ENSCCAP00000015973	ENSCCAP00000024812	Ankyrin repeat domain 31.	Coiled-coil domain containing 36.	0.526
ANKRD31	SYCE1	ENSCCAP00000015973	ENSCCAP00000020291	Ankyrin repeat domain 31.	Synaptonemal complex central element protein 1.	0.449
ANKRD31	SYCE2	ENSCCAP00000015973	ENSCCAP00000031925	Ankyrin repeat domain 31.	Synaptonemal complex central element protein 2.	0.403
ANKRD31	SYCP1	ENSCCAP00000015973	ENSCCAP00000032513	Ankyrin repeat domain 31.	Synaptonemal complex protein 1.	0.489
ANKRD31	TEX15	ENSCCAP00000015973	ENSCCAP00000025766	Ankyrin repeat domain 31.	Testis expressed 15, meiosis and synapsis associated.	0.403
ATM	ATRX	ENSCCAP00000021607	ENSCCAP00000015231	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	ATRX chromatin remodeler.	0.618
ATM	BRIP1	ENSCCAP00000021607	ENSCCAP00000013780	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	BRCA1 interacting protein C-terminal helicase 1.	0.740
ATM	DMC1	ENSCCAP00000021607	ENSCCAP00000008970	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	0.625
ATM	ENSCCAP00000000393	ENSCCAP00000021607	ENSCCAP00000000393	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Uncharacterized protein.	0.625
ATM	ENSCCAP00000015138	ENSCCAP00000021607	ENSCCAP00000015138	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	TRF domain-containing protein.	0.409
ATM	ENSCCAP00000028238	ENSCCAP00000021607	ENSCCAP00000028238	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.409
ATM	ENSCCAP00000031489	ENSCCAP00000021607	ENSCCAP00000031489	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	HTH myb-type domain-containing protein.	0.409
ATM	FANCD2	ENSCCAP00000021607	ENSCCAP00000037517	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	FA complementation group D2.	0.760
ATM	LOC108317875	ENSCCAP00000021607	ENSCCAP00000013129	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	RECA_2 domain-containing protein.	0.752
ATM	MEIOB	ENSCCAP00000021607	ENSCCAP00000014680	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Meiosis specific with OB-fold.	0.726
ATM	MLH1	ENSCCAP00000021607	ENSCCAP00000004766	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	MutL homolog 1.	0.867
ATM	MLH3	ENSCCAP00000021607	ENSCCAP00000021672	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	MutL homolog 3.	0.746
ATM	MSH4	ENSCCAP00000021607	ENSCCAP00000033538	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.785
ATM	MSH5	ENSCCAP00000021607	ENSCCAP00000032152	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.620
ATM	RAD51	ENSCCAP00000021607	ENSCCAP00000009344	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.939