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| | ATP6AP1 | ATPase H+ transporting accessory protein 1. (468 aa) |
| | PDLIM1 | PDZ and LIM domain 1. (329 aa) |
| | CHRNA7 | Uncharacterized protein. (502 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | ADO | 2-aminoethanethiol dioxygenase. (270 aa) |
| | TM9SF4 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (747 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | VHLL | VHL domain-containing protein. (122 aa) |
| | NOS1 | Nitric oxide synthase 1. (1468 aa) |
| | FABP1 | Fatty acid binding protein 1. (127 aa) |
| | FAM167A | Family with sequence similarity 167 member A. (215 aa) |
| | BMP2 | Bone morphogenetic protein 2. (396 aa) |
| | PICK1 | Protein interacting with PRKCA 1. (415 aa) |
| | ATP7A | ATPase copper transporting alpha. (1476 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (326 aa) |
| | BNIP2 | CRAL-TRIO domain-containing protein. (428 aa) |
| | ENSCCAP00000003927 | Uncharacterized protein. (618 aa) |
| | ARNT2 | Aryl hydrocarbon receptor nuclear translocator 2. (717 aa) |
| | PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (199 aa) |
| | ENSCCAP00000004220 | Uncharacterized protein; Belongs to the complex I LYR family. (70 aa) |
| | CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (405 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (275 aa) |
| | ITGA2 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa) |
| | ENSCCAP00000005127 | A_deaminase domain-containing protein. (260 aa) |
| | EDN1 | Endothelin 1. (212 aa) |
| | ALKBH5 | AlkB homolog 5, RNA demethylase. (394 aa) |
| | VCAM1 | Vascular cell adhesion molecule 1. (739 aa) |
| | BCL2 | BCL2 apoptosis regulator. (240 aa) |
| | CLDN3 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | PDK3 | Protein-serine/threonine kinase. (415 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | ATP6V1A | ATPase H+ transporting V1 subunit A. (606 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa) |
| | NGB | Neuroglobin; Belongs to the globin family. (151 aa) |
| | COL1A1 | Collagen type I alpha 1 chain. (1464 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (230 aa) |
| | PDPN | Podoplanin. (207 aa) |
| | SLC11A2 | Solute carrier family 11 member 2. (537 aa) |
| | CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa) |
| | ENSCCAP00000006951 | Uncharacterized protein; Belongs to the adenylate kinase family. (186 aa) |
| | CYBA | Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (193 aa) |
| | ADM | Adrenomedullin. (184 aa) |
| | NDNF | Neuron derived neurotrophic factor. (568 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | HP1BP3 | Heterochromatin protein 1 binding protein 3. (515 aa) |
| | MMP2 | Matrix metallopeptidase 2. (660 aa) |
| | EGLN1 | Uncharacterized protein. (426 aa) |
| | AQP3 | Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa) |
| | GATA6 | GATA binding protein 6. (592 aa) |
| | ENSCCAP00000008212 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (91 aa) |
| | HMOX2 | Heme oxygenase 2. (338 aa) |
| | FNDC1 | Fibronectin type III domain containing 1. (1883 aa) |
| | REST | RE1 silencing transcription factor. (1100 aa) |
| | ADAM15 | ADAM metallopeptidase domain 15. (848 aa) |
| | SRC | Tyrosine-protein kinase. (542 aa) |
| | ENSCCAP00000008905 | Uncharacterized protein. (76 aa) |
| | BMP7 | Bone morphogenetic protein 7. (430 aa) |
| | SIRT2 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa) |
| | CYBB | Cytochrome b-245 beta chain. (570 aa) |
| | BACH1 | BTB domain and CNC homolog 1. (736 aa) |
| | RYR1 | Ryanodine receptor 1. (4990 aa) |
| | HMOX1 | Heme oxygenase 1. (297 aa) |
| | TIGAR | TP53 induced glycolysis regulatory phosphatase. (270 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa) |
| | STUB1 | STIP1 homology and U-box containing protein 1. (311 aa) |
| | KCNK2 | Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa) |
| | NDRG1 | N-myc downstream regulated 1. (394 aa) |
| | LMNA | Lamin A/C; Belongs to the intermediate filament family. (677 aa) |
| | PDK1 | Protein-serine/threonine kinase. (447 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (712 aa) |
| | ENSCCAP00000011758 | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (191 aa) |
| | LOC108315475 | C2 domain-containing protein. (141 aa) |
| | SLC7A5 | Solute carrier family 7 member 5. (509 aa) |
| | P2RX3 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa) |
| | CARD16 | Caspase recruitment domain family member 16. (185 aa) |
| | POU4F2 | POU domain protein. (408 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | ENSCCAP00000013269 | CRAL-TRIO domain-containing protein. (295 aa) |
| | NDUFS2 | NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (463 aa) |
| | BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (1212 aa) |
| | HSP90B1 | HATPase_c domain-containing protein. (804 aa) |
| | NOL3 | Nucleolar protein 3. (258 aa) |
| | SLC1A1 | Amino acid transporter. (524 aa) |
| | FUNDC1 | Uncharacterized protein. (155 aa) |
| | ANGPTL4 | Angiopoietin like 4. (411 aa) |
| | REG1B | Regenerating family member 1 beta. (166 aa) |
| | ANGPT2 | Angiopoietin 2. (455 aa) |
| | FAM167B | Family with sequence similarity 167 member B. (163 aa) |
| | NOP53 | Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (478 aa) |
| | PML | Promyelocytic leukemia. (880 aa) |
| | TMEM199 | Transmembrane protein 199. (208 aa) |
| | PLOD2 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (758 aa) |
| | CREBBP | CREB binding protein. (2448 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | ENG | Endoglin. (655 aa) |
| | LONP1 | Lon protease homolog; Belongs to the peptidase S16 family. (858 aa) |
| | SLC2A8 | Solute carrier family 2 member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (477 aa) |
| | CCDC115 | Coiled-coil domain containing 115. (180 aa) |
| | SUV39H2 | Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (410 aa) |
| | HYOU1 | Hypoxia up-regulated 1. (1000 aa) |
| | PLAU | Plasminogen activator, urokinase. (430 aa) |
| | RORA | RAR related orphan receptor A. (489 aa) |
| | CHRNA4 | Cholinergic receptor nicotinic alpha 4 subunit. (626 aa) |
| | BBC3 | BCL2 binding component 3. (261 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa) |
| | PMAIP1 | Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa) |
| | FAS | Fas cell surface death receptor. (317 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (990 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | LIMD1 | LIM domains containing 1. (676 aa) |
| | PDGFA | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (211 aa) |
| | PLEKHN1 | Pleckstrin homology domain containing N1. (621 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (846 aa) |
| | NF1 | Neurofibromin 1. (2839 aa) |
| | PLAT | Plasminogen activator; Belongs to the peptidase S1 family. (563 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | AK4 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa) |
| | STOX1 | Storkhead box 1. (988 aa) |
| | TBL2 | Transducin beta like 2. (446 aa) |
| | CIAO3 | Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family. (471 aa) |
| | TSC1 | TSC complex subunit 1. (1149 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR. (2508 aa) |
| | ATP6V0A2 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa) |
| | HIF1AN | Hypoxia inducible factor 1 subunit alpha inhibitor. (349 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3000 aa) |
| | HIF1A | Uncharacterized protein. (848 aa) |
| | HIF3A | Hypoxia inducible factor 3 subunit alpha. (670 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2720 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa) |
| | NR4A2 | Nuclear receptor subfamily 4 group A member 2. (598 aa) |
| | MT3 | Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (113 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | LPAR1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | NKX3-1 | NK3 homeobox 1. (223 aa) |
| | HSF1 | Heat shock transcription factor 1. (532 aa) |
| | ARNT | Aryl hydrocarbon receptor nuclear translocator. (789 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (468 aa) |
| | TGFBR3 | Transforming growth factor beta receptor 3. (851 aa) |
| | PINK1 | PTEN induced kinase 1. (581 aa) |
| | KCNMB1 | Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa) |
| | SIRT1 | Sirtuin 1. (446 aa) |
| | TH | Tyrosine hydroxylase. (527 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (232 aa) |
| | ERO1A | Endoplasmic reticulum oxidoreductase 1 alpha. (468 aa) |
| | MST1 | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa) |
| | ENSCCAP00000024245 | Peptidyl-prolyl cis-trans isomerase. (141 aa) |
| | STC1 | Stanniocalcin 1. (248 aa) |
| | CASR | Calcium sensing receptor. (1077 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | PRKCE | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa) |
| | NPPC | Natriuretic peptide C. (127 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa) |
| | CBL | Cbl proto-oncogene. (909 aa) |
| | RTN4 | Reticulon. (1194 aa) |
| | ADA | A_deaminase domain-containing protein. (363 aa) |
| | ENSCCAP00000025755 | Thioredoxin domain-containing protein. (154 aa) |
| | NARF | Nuclear prelamin A recognition factor; Belongs to the NARF family. (478 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1121 aa) |
| | GUCY1A2 | Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (727 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (314 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (487 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (244 aa) |
| | SLC8A1 | Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (600 aa) |
| | ENSCCAP00000026832 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (294 aa) |
| | UCP3 | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa) |
| | HK2 | Hexokinase 2. (917 aa) |
| | EEF2K | Eukaryotic elongation factor 2 kinase. (725 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1108 aa) |
| | LOC108293547 | Uncharacterized protein. (773 aa) |
| | VHL | Von Hippel-Lindau tumor suppressor. (189 aa) |
| | KCNK3 | Potassium channel subfamily K member. (395 aa) |
| | TXN2 | Thioredoxin 2. (162 aa) |
| | E2F1 | E2F transcription factor 1. (438 aa) |
| | LOXL2 | Lysyl oxidase like 2. (774 aa) |
| | HSD11B2 | Hydroxysteroid 11-beta dehydrogenase 2. (405 aa) |
| | OPRD1 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (372 aa) |
| | MGARP | Mitochondria localized glutamic acid rich protein. (241 aa) |
| | RGCC | Regulator of cell cycle. (137 aa) |
| | KCNA5 | Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (602 aa) |
| | SCFD1 | Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (638 aa) |
| | CPEB2 | Cytoplasmic polyadenylation element binding protein 2. (593 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (395 aa) |
| | NOX1 | NADPH oxidase 1. (564 aa) |
| | USF1 | Upstream transcription factor 1. (310 aa) |
| | ABAT | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa) |
| | MPL | MPL proto-oncogene, thrombopoietin receptor. (635 aa) |
| | RBPJ | Recombination signal binding protein for immunoglobulin kappa J region. (521 aa) |
| | SLC2A4 | Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa) |
| | AIFM1 | Apoptosis inducing factor mitochondria associated 1. (612 aa) |
| | ALAS2 | 5-aminolevulinate synthase. (587 aa) |
| | ATP6V0D1 | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (388 aa) |
| | EPO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (194 aa) |
| | SLC8A3 | Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (469 aa) |
| | CHRNB2 | Cholinergic receptor nicotinic beta 2 subunit. (502 aa) |
| | P2RX2 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (472 aa) |
| | SLC2A1 | Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (508 aa) |
| | CA9 | Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. (454 aa) |
| | NFE2L2 | Nuclear factor, erythroid 2 like 2. (606 aa) |
| | BNIP3 | BCL2 interacting protein 3. (250 aa) |
| | EPAS1 | Endothelial PAS domain protein 1. (867 aa) |
| | BNIP1 | BCL2 interacting protein 1. (228 aa) |
| | LOXL3 | Lysyl oxidase like 3. (753 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (403 aa) |
| | ENSCCAP00000032799 | Uncharacterized protein. (131 aa) |
| | PPARD | Peroxisome proliferator activated receptor delta. (441 aa) |
| | WDR83 | WD repeat domain 83. (315 aa) |
| | GUCY1B1 | Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (635 aa) |
| | CCN2 | Cellular communication network factor 2. (349 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa) |
| | NOTCH1 | Notch receptor 1. (2550 aa) |
| | THBS1 | Thrombospondin 1. (1178 aa) |
| | TXNRD2 | Thioredoxin reductase 2. (523 aa) |
| | CD24 | Uncharacterized protein. (78 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1189 aa) |
| | PAM | Peptidylglycine alpha-amidating monooxygenase. (976 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (707 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | ENSCCAP00000034672 | RanBP2-type domain-containing protein. (434 aa) |
| | DDR2 | Discoidin domain receptor tyrosine kinase 2. (855 aa) |
| | CBFA2T3 | Uncharacterized protein. (653 aa) |
| | ADAM17 | ADAM metallopeptidase domain 17. (914 aa) |
| | NPEPPS | Aminopeptidase. (910 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) |
| | EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa) |
| | MYOCD | Myocardin. (987 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | AJUBA | Ajuba LIM protein. (539 aa) |
| | PENK | Proenkephalin. (267 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | EIF4EBP1 | Eukaryotic translation initiation factor 4E binding protein 1. (118 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (205 aa) |
| | P4HB | Protein disulfide-isomerase. (510 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1305 aa) |
| | MYOD1 | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa) |
| | EGLN2 | Egl-9 family hypoxia inducible factor 2. (406 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (356 aa) |
| | KCNMA1 | Potassium calcium-activated channel subfamily M alpha 1. (1280 aa) |
| | EP300 | E1A binding protein p300. (2420 aa) |
| | LOC108317622 | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1981 aa) |
| | FOXO1 | Forkhead box O1. (654 aa) |
| | UCP2 | Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa) |
| | CPEB4 | Cytoplasmic polyadenylation element binding protein 4. (729 aa) |
| | CYGB | Cytoglobin; Belongs to the globin family. (192 aa) |
| | RYR2 | Ryanodine receptor 2. (4922 aa) |
| | AQP1 | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa) |
| | DPP4 | Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (739 aa) |
| | MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa) |
| | ATP6V1G1 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa) |
| | CPEB1 | Uncharacterized protein. (612 aa) |
| | GUCY1A1 | Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa) |
| | EGLN3 | Egl-9 family hypoxia inducible factor 3. (239 aa) |
| | SCAP | SREBF chaperone. (1267 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | SLC29A1 | Solute carrier family 29 member 1 (Augustine blood group). (481 aa) |
| | DNMT3A | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa) |
| | BNIP3L | BCL2 interacting protein 3 like. (219 aa) |
| | ANGPT4 | Angiopoietin 4. (503 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa) |
| | SRF | Serum response factor. (509 aa) |
| | WTIP | WT1 interacting protein. (429 aa) |
| | CYB5R4 | Cytochrome b5 reductase 4. (498 aa) |
