STRINGSTRING
WNT6 WNT6 RGMA RGMA LOC108291510 LOC108291510 SEC24B SEC24B ENSCCAP00000000953 ENSCCAP00000000953 GATA3 GATA3 SOX11 SOX11 RET RET TRAF6 TRAF6 DLC1 DLC1 CLUAP1 CLUAP1 SOX9 SOX9 HECTD1 HECTD1 FZD2 FZD2 BRD2 BRD2 LOC108284013 LOC108284013 TMED2 TMED2 CITED2 CITED2 NOG NOG PHACTR4 PHACTR4 DEAF1 DEAF1 GDNF GDNF ENSCCAP00000006235 ENSCCAP00000006235 TULP3 TULP3 LOC108316601 LOC108316601 ADM ADM LOC108308464 LOC108308464 PTCH1 PTCH1 SIX1 SIX1 RARA RARA OPA1 OPA1 PRKACB PRKACB LHX2 LHX2 BMP7 BMP7 LOC108314885 LOC108314885 CEP290 CEP290 MTHFD1 MTHFD1 ARHGAP35 ARHGAP35 IFT52 IFT52 GRHL2 GRHL2 SHROOM3 SHROOM3 WNT4 WNT4 MIB1 MIB1 LRRC1 LRRC1 KAT2A KAT2A ENSCCAP00000012791 ENSCCAP00000012791 IRX2 IRX2 BMP5 BMP5 SOX8 SOX8 ABL1 ABL1 TRIM71 TRIM71 SUFU SUFU TBXT TBXT CC2D2A CC2D2A BBS4 BBS4 COBL COBL ENSCCAP00000015218 ENSCCAP00000015218 STK3 STK3 ENSCCAP00000015685 ENSCCAP00000015685 CTNNB1 CTNNB1 HS2ST1 HS2ST1 WNT5A WNT5A CTHRC1 CTHRC1 KDM6A KDM6A STK4 STK4 HES5 HES5 PLXNB2 PLXNB2 TGFB2 TGFB2 SFRP2 SFRP2 RARG RARG TSC1 TSC1 ST14 ST14 SKI SKI FGF8 FGF8 RPS7 RPS7 HIF1A HIF1A MTHFR MTHFR FGFR2 FGFR2 SETD2 SETD2 LUZP1 LUZP1 OVOL2 OVOL2 OSR1 OSR1 PODXL PODXL VASP VASP SALL4 SALL4 IRX3 IRX3 HESX1 HESX1 RALA RALA SFRP1 SFRP1 TEAD2 TEAD2 FGF10 FGF10 FZD3 FZD3 LMO4 LMO4 KDM2B KDM2B TGFB1 TGFB1 LOC108293547 LOC108293547 PRICKLE1 PRICKLE1 SOX4 SOX4 KIF20B KIF20B MKS1 MKS1 TCTN1 TCTN1 NODAL NODAL DVL2 DVL2 STIL STIL CECR2 CECR2 IRX1 IRX1 SHANK3 SHANK3 SCRIB SCRIB CELSR1 CELSR1 MED12 MED12 MTHFD1L MTHFD1L LRP2 LRP2 ENSCCAP00000032572 ENSCCAP00000032572 LIAS LIAS VANGL2 VANGL2 IFT122 IFT122 PROX1 PROX1 SEMA4C SEMA4C GRHL3 GRHL3 DVL3 DVL3 GDF7 GDF7 PAX2 PAX2 GLMN GLMN TCAP TCAP SPINT1 SPINT1 FUZ FUZ LIAS-2 LIAS-2 BCL10 BCL10 SDC4 SDC4 APAF1 APAF1 IFT172 IFT172 BMP4 BMP4 LOC108301643 LOC108301643 HAND1 HAND1 TSC2 TSC2 PTK7 PTK7 DVL1 DVL1 ENSCCAP00000039965 ENSCCAP00000039965 FZD6 FZD6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (453 aa)
LOC10829151040S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1244 aa)
ENSCCAP00000000953Uncharacterized protein. (966 aa)
GATA3GATA binding protein 3. (444 aa)
SOX11Transcription factor SOX. (450 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1113 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
DLC1DLC1 Rho GTPase activating protein. (1528 aa)
CLUAP1Clusterin associated protein 1. (383 aa)
SOX9SRY-box transcription factor 9. (509 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2610 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
BRD2Uncharacterized protein. (808 aa)
LOC10828401340S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
TMED2Transmembrane p24 trafficking protein 2. (208 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (275 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
PHACTR4Phosphatase and actin regulator. (712 aa)
DEAF1DEAF1 transcription factor. (565 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
ENSCCAP00000006235Uncharacterized protein. (678 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (395 aa)
LOC10831660140S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (189 aa)
ADMAdrenomedullin. (184 aa)
LOC10830846440S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (190 aa)
PTCH1Patched 1. (1452 aa)
SIX1SIX homeobox 1. (284 aa)
RARARetinoic acid receptor alpha. (464 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
LHX2LIM homeobox 2. (406 aa)
BMP7Bone morphogenetic protein 7. (430 aa)
LOC108314885Uncharacterized protein. (768 aa)
CEP290Centrosomal protein 290. (2457 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (935 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
IFT52Intraflagellar transport 52. (424 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
SHROOM3Shroom family member 3. (1995 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
KAT2ALysine acetyltransferase 2A. (839 aa)
ENSCCAP00000012791Uncharacterized protein. (502 aa)
IRX2Iroquois homeobox 2. (471 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
SOX8SRY-box transcription factor 8. (446 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
TRIM71Tripartite motif containing 71. (868 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (522 aa)
TBXTT-box transcription factor T. (434 aa)
CC2D2ACoiled-coil and C2 domain containing 2A. (1620 aa)
BBS4Bardet-Biedl syndrome 4. (494 aa)
COBLCordon-bleu WH2 repeat protein. (1270 aa)
ENSCCAP00000015218Folate_rec domain-containing protein. (228 aa)
STK3Serine/threonine kinase 3. (523 aa)
ENSCCAP00000015685Uncharacterized protein. (153 aa)
CTNNB1Catenin beta 1. (781 aa)
HS2ST1Uncharacterized protein. (356 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
CTHRC1Collagen triple helix repeat containing 1. (243 aa)
KDM6ALysine demethylase 6A. (1249 aa)
STK4Serine/threonine kinase 4. (487 aa)
HES5Hes family bHLH transcription factor 5. (162 aa)
PLXNB2Plexin B2. (1839 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SFRP2Secreted frizzled related protein 2. (296 aa)
RARGRetinoic acid receptor gamma. (456 aa)
TSC1TSC complex subunit 1. (1149 aa)
ST14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa)
SKISKI proto-oncogene. (729 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
RPS740S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
HIF1AUncharacterized protein. (848 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (656 aa)
FGFR2Fibroblast growth factor receptor. (782 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2485 aa)
LUZP1Leucine zipper protein 1. (1074 aa)
OVOL2Ovo like zinc finger 2. (275 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
PODXLPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (506 aa)
VASPWH1 domain-containing protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (380 aa)
SALL4Uncharacterized protein. (1012 aa)
IRX3Iroquois homeobox 3. (501 aa)
HESX1HESX homeobox 1. (185 aa)
RALARAS like proto-oncogene A. (206 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
TEAD2TEA domain transcription factor 2. (451 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
LMO4LIM domain only 4. (165 aa)
KDM2BLysine demethylase 2B. (1349 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (314 aa)
LOC108293547Uncharacterized protein. (773 aa)
PRICKLE1Prickle planar cell polarity protein 1. (829 aa)
SOX4Transcription factor SOX. (470 aa)
KIF20BKinesin family member 20B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1801 aa)
MKS1Uncharacterized protein. (559 aa)
TCTN1DUF1619 domain-containing protein. (233 aa)
NODALNodal growth differentiation factor. (347 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
STILSTIL centriolar assembly protein. (1221 aa)
CECR2CECR2 histone acetyl-lysine reader. (1431 aa)
IRX1Iroquois homeobox 1. (480 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1732 aa)
SCRIBScribble planar cell polarity protein. (1655 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (3006 aa)
MED12Mediator complex subunit 12. (2200 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (944 aa)
LRP2LDL receptor related protein 2. (4656 aa)
ENSCCAP00000032572WH1 domain-containing protein. (355 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa)
VANGL2Vang-like protein. (542 aa)
IFT122Intraflagellar transport 122. (1269 aa)
PROX1Prospero homeobox 1. (737 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (874 aa)
GRHL3Grainyhead like transcription factor 3. (626 aa)
DVL3Uncharacterized protein. (716 aa)
GDF7Growth differentiation factor 7. (455 aa)
PAX2Paired box 2. (417 aa)
GLMNGlomulin, FKBP associated protein. (595 aa)
TCAPTitin-cap. (167 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (531 aa)
FUZFuzzy planar cell polarity protein. (418 aa)
LIAS-2Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (342 aa)
BCL10BCL10 immune signaling adaptor. (309 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (199 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
IFT172Uncharacterized protein. (1602 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
LOC108301643Uncharacterized protein. (400 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
TSC2TSC complex subunit 2. (1777 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
DVL1Dishevelled segment polarity protein 1. (695 aa)
ENSCCAP00000039965Uncharacterized protein. (374 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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