STRINGSTRING
ITPRIPL2 ITPRIPL2 LOC108293227 LOC108293227 EYA2 EYA2 BAD BAD LOC108308592 LOC108308592 FADD FADD NGF NGF TNFRSF1B TNFRSF1B BCL2 BCL2 SMAD3 SMAD3 TNFRSF10B TNFRSF10B PIK3R1 PIK3R1 IL33 IL33 BCL2A1 BCL2A1 DAPK1 DAPK1 CASP7 CASP7 RB1CC1 RB1CC1 BCL2L11 BCL2L11 JAK2 JAK2 ENSCCAP00000011501 ENSCCAP00000011501 BCL2L1 BCL2L1 BAX BAX ENSCCAP00000011961 ENSCCAP00000011961 ITGAV ITGAV ENSCCAP00000012433 ENSCCAP00000012433 CASP8AP2 CASP8AP2 HIPK1 HIPK1 SORT1 SORT1 MKNK2 MKNK2 TRADD TRADD GSK3B GSK3B INHBA INHBA TNFSF12 TNFSF12 STK3 STK3 LOC108315637 LOC108315637 PML PML IL2 IL2 DDX47 DDX47 TLR3 TLR3 DAB2IP DAB2IP GABARAP GABARAP KRT18 KRT18 STK4 STK4 KITLG KITLG FAS FAS LOC108295625 LOC108295625 TGFB1 TGFB1 TGFB2 TGFB2 NDUFA13 NDUFA13 IFNG IFNG NF1 NF1 TNF TNF CASP8 CASP8 TNFRSF10A TNFRSF10A BOK BOK CTNNA1 CTNNA1 CD70 CD70 IFI27 IFI27 MCL1 MCL1 RNF41 RNF41 ZDHHC3 ZDHHC3 PTPRC PTPRC FGFR3 FGFR3 SFRP1 SFRP1 PDIA3 PDIA3 FGF10 FGF10 SKIL SKIL EYA1 EYA1 RIPK1 RIPK1 GSK3A GSK3A CASP2 CASP2 GABARAPL1 GABARAPL1 BCL2L10 BCL2L10 SIVA1 SIVA1 LOC108300326 LOC108300326 CD27 CD27 ENSCCAP00000029150 ENSCCAP00000029150 PIDD1 PIDD1 DEDD DEDD IL7 IL7 WWOX WWOX DELE1 DELE1 ENSCCAP00000031376 ENSCCAP00000031376 SGPP1 SGPP1 ACVR1B ACVR1B DEDD2 DEDD2 ERBB3 ERBB3 CTTN CTTN IL12A IL12A YAP1 YAP1 DAXX DAXX BID BID IL6R IL6R CX3CL1 CX3CL1 TNFRSF1A TNFRSF1A COL2A1 COL2A1 FASLG FASLG LOC108282374 LOC108282374 PDPK1 PDPK1 BAG3 BAG3 BAK1 BAK1 PARP2 PARP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITPRIPL2ITPRIP like 2. (536 aa)
LOC108293227Uncharacterized protein. (819 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (538 aa)
BADBCL2 associated agonist of cell death. (167 aa)
LOC108308592IF rod domain-containing protein; Belongs to the intermediate filament family. (429 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (241 aa)
TNFRSF1BTNF receptor superfamily member 1B. (462 aa)
BCL2BCL2 apoptosis regulator. (240 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
TNFRSF10BTNF receptor superfamily member 10b. (443 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
IL33Interleukin 33. (269 aa)
BCL2A1BCL2 related protein A1. (168 aa)
DAPK1Death associated protein kinase 1. (1430 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (304 aa)
RB1CC1RB1 inducible coiled-coil 1. (1594 aa)
BCL2L11BCL2 like 11. (200 aa)
JAK2Tyrosine-protein kinase. (1136 aa)
ENSCCAP00000011501IF rod domain-containing protein; Belongs to the intermediate filament family. (399 aa)
BCL2L1BCL2 like 1. (233 aa)
BAXBCL2 associated X, apoptosis regulator. (159 aa)
ENSCCAP00000011961Uncharacterized protein. (121 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1047 aa)
ENSCCAP00000012433Uncharacterized protein. (114 aa)
CASP8AP2Caspase 8 associated protein 2. (1976 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
SORT1Sortilin. (831 aa)
MKNK2MAPK interacting serine/threonine kinase 2. (509 aa)
TRADDTNFRSF1A associated via death domain. (312 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (434 aa)
INHBAInhibin subunit beta A. (426 aa)
TNFSF12TNF superfamily member 12; Belongs to the tumor necrosis factor family. (249 aa)
STK3Serine/threonine kinase 3. (523 aa)
LOC108315637IF rod domain-containing protein; Belongs to the intermediate filament family. (425 aa)
PMLPromyelocytic leukemia. (880 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
DDX47DEAD-box helicase 47; Belongs to the DEAD box helicase family. (455 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
DAB2IPDAB2 interacting protein. (1193 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
KRT18IF rod domain-containing protein; Belongs to the intermediate filament family. (315 aa)
STK4Serine/threonine kinase 4. (487 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (268 aa)
FASFas cell surface death receptor. (317 aa)
LOC108295625USP8_interact domain-containing protein. (287 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (314 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
NDUFA13Uncharacterized protein. (144 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
NF1Neurofibromin 1. (2839 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (522 aa)
TNFRSF10ATNF receptor superfamily member 10a. (419 aa)
BOKBCL2 family apoptosis regulator BOK. (212 aa)
CTNNA1Catenin alpha 1. (905 aa)
CD70CD70 molecule; Belongs to the tumor necrosis factor family. (187 aa)
IFI27Interferon alpha inducible protein 27. (126 aa)
MCL1MCL1 apoptosis regulator, BCL2 family member. (352 aa)
RNF41RING-type domain-containing protein. (155 aa)
ZDHHC3Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (331 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1299 aa)
FGFR3Fibroblast growth factor receptor. (808 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
PDIA3Protein disulfide isomerase family A member 3. (417 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
SKILSKI like proto-oncogene. (684 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (610 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
GABARAPL1GABA type A receptor associated protein like 1. (146 aa)
BCL2L10BCL2 like 10. (229 aa)
SIVA1Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (175 aa)
LOC108300326Protein BEX3-like. (106 aa)
CD27CD27 molecule. (260 aa)
ENSCCAP00000029150IF rod domain-containing protein; Belongs to the intermediate filament family. (414 aa)
PIDD1P53-induced death domain protein 1. (910 aa)
DEDDDeath effector domain containing. (318 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (177 aa)
WWOXWW domain containing oxidoreductase. (414 aa)
DELE1DAP3 binding cell death enhancer 1. (517 aa)
ENSCCAP00000031376Uncharacterized protein. (129 aa)
SGPP1Sphingosine-1-phosphate phosphatase 1. (441 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (544 aa)
DEDD2Death effector domain containing 2. (326 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1352 aa)
CTTNCortactin. (600 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (289 aa)
YAP1Uncharacterized protein. (506 aa)
DAXXDaxx domain-containing protein. (750 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (236 aa)
IL6RInterleukin 6 receptor. (468 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (335 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (281 aa)
LOC108282374Uncharacterized protein. (330 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (562 aa)
BAG3BCL2 associated athanogene 3. (576 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
PARP2Poly [ADP-ribose] polymerase. (570 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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