STRINGSTRING
SNF8 SNF8 STAM STAM ATP13A2 ATP13A2 HGS HGS SDC1 SDC1 PDCD6IP PDCD6IP CHMP2A CHMP2A SDCBP SDCBP SDC4 SDC4 TSG101 TSG101 RAB7A RAB7A SMPD3 SMPD3 VPS4A VPS4A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNF8SNF8 subunit of ESCRT-II. (299 aa)
STAMSignal transducing adaptor molecule. (540 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1204 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (802 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
PDCD6IPProgrammed cell death 6 interacting protein. (873 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
SDCBPSyndecan binding protein. (317 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (199 aa)
TSG101Tumor susceptibility 101. (395 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
Server load: low (24%) [HD]