node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHMP2A | HGS | ENSCCAP00000033976 | ENSCCAP00000026795 | Charged multivesicular body protein 2A. | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.966 |
CHMP2A | PDCD6IP | ENSCCAP00000033976 | ENSCCAP00000030041 | Charged multivesicular body protein 2A. | Programmed cell death 6 interacting protein. | 0.642 |
CHMP2A | SNF8 | ENSCCAP00000033976 | ENSCCAP00000016014 | Charged multivesicular body protein 2A. | SNF8 subunit of ESCRT-II. | 0.937 |
CHMP2A | STAM | ENSCCAP00000033976 | ENSCCAP00000022445 | Charged multivesicular body protein 2A. | Signal transducing adaptor molecule. | 0.626 |
CHMP2A | TSG101 | ENSCCAP00000033976 | ENSCCAP00000036546 | Charged multivesicular body protein 2A. | Tumor susceptibility 101. | 0.908 |
CHMP2A | VPS4A | ENSCCAP00000033976 | ENSCCAP00000037564 | Charged multivesicular body protein 2A. | Uncharacterized protein; Belongs to the AAA ATPase family. | 0.991 |
HGS | CHMP2A | ENSCCAP00000026795 | ENSCCAP00000033976 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Charged multivesicular body protein 2A. | 0.966 |
HGS | PDCD6IP | ENSCCAP00000026795 | ENSCCAP00000030041 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Programmed cell death 6 interacting protein. | 0.659 |
HGS | SNF8 | ENSCCAP00000026795 | ENSCCAP00000016014 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | SNF8 subunit of ESCRT-II. | 0.901 |
HGS | STAM | ENSCCAP00000026795 | ENSCCAP00000022445 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Signal transducing adaptor molecule. | 0.996 |
HGS | TSG101 | ENSCCAP00000026795 | ENSCCAP00000036546 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Tumor susceptibility 101. | 0.991 |
HGS | VPS4A | ENSCCAP00000026795 | ENSCCAP00000037564 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Uncharacterized protein; Belongs to the AAA ATPase family. | 0.583 |
PDCD6IP | CHMP2A | ENSCCAP00000030041 | ENSCCAP00000033976 | Programmed cell death 6 interacting protein. | Charged multivesicular body protein 2A. | 0.642 |
PDCD6IP | HGS | ENSCCAP00000030041 | ENSCCAP00000026795 | Programmed cell death 6 interacting protein. | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.659 |
PDCD6IP | SDC1 | ENSCCAP00000030041 | ENSCCAP00000027451 | Programmed cell death 6 interacting protein. | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. | 0.503 |
PDCD6IP | SDCBP | ENSCCAP00000030041 | ENSCCAP00000034743 | Programmed cell death 6 interacting protein. | Syndecan binding protein. | 0.866 |
PDCD6IP | SNF8 | ENSCCAP00000030041 | ENSCCAP00000016014 | Programmed cell death 6 interacting protein. | SNF8 subunit of ESCRT-II. | 0.510 |
PDCD6IP | STAM | ENSCCAP00000030041 | ENSCCAP00000022445 | Programmed cell death 6 interacting protein. | Signal transducing adaptor molecule. | 0.551 |
PDCD6IP | TSG101 | ENSCCAP00000030041 | ENSCCAP00000036546 | Programmed cell death 6 interacting protein. | Tumor susceptibility 101. | 0.942 |
PDCD6IP | VPS4A | ENSCCAP00000030041 | ENSCCAP00000037564 | Programmed cell death 6 interacting protein. | Uncharacterized protein; Belongs to the AAA ATPase family. | 0.868 |