(37 nodes) Regulation of sprouting angiogenesis network (Cebus capucinus)

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second shell of interactors

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Predicted Interactions

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Your Input:
	ITGA5	Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1050 aa)
	JAK1	Tyrosine-protein kinase. (1153 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (287 aa)
	LOC108285741	Uncharacterized protein. (491 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
	GHRL	Ghrelin and obestatin prepropeptide. (117 aa)
	JMJD8	Jumonji domain containing 8. (264 aa)
	SYNJ2BP	Synaptojanin 2 binding protein. (145 aa)
	JCAD	Junctional cadherin 5 associated. (1350 aa)
	E2F2	E2F transcription factor 2. (435 aa)
	SEMA6A	Semaphorin 6A; Belongs to the semaphorin family. (1047 aa)
	FGF1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	EPN1	Epsin 1. (655 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (562 aa)
	TJP1	Tight junction protein 1; Belongs to the MAGUK family. (1765 aa)
	CREB3L1	cAMP responsive element binding protein 3 like 1. (519 aa)
	ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif 9. (1935 aa)
	IL10	Interleukin 10. (178 aa)
	TNN	Tenascin N. (1191 aa)
	KLF4	Kruppel like factor 4. (477 aa)
	THBS1	Thrombospondin 1. (1178 aa)
	EPN2	Epsin 2. (641 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	PPP1R16B	Protein phosphatase 1 regulatory subunit 16B. (567 aa)
	ENSCCAP00000024393	Uncharacterized protein. (69 aa)
	LOC108301202	Pyruvate kinase; Belongs to the pyruvate kinase family. (512 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
	ALOX5	Arachidonate 5-lipoxygenase. (674 aa)
	GHSR	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
	BMPER	BMP binding endothelial regulator. (664 aa)
	ENSCCAP00000018653	Uncharacterized protein. (198 aa)
	KLF2	Kruppel like factor 2. (354 aa)
	LOC108297965	Pyruvate kinase; Belongs to the pyruvate kinase family. (471 aa)
	LOC108316462	Uncharacterized protein. (199 aa)
	RHOJ	Ras homolog family member J. (214 aa)
	GLUL	Glutamine synthetase. (374 aa)
	PKM	Pyruvate kinase; Belongs to the pyruvate kinase family. (539 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FGF1	FGF2	ENSCCAP00000039927	ENSCCAP00000011527	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.643
FGF1	PIK3CB	ENSCCAP00000039927	ENSCCAP00000021785	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.513
FGF2	FGF1	ENSCCAP00000011527	ENSCCAP00000039927	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.643
FGF2	GLUL	ENSCCAP00000011527	ENSCCAP00000014213	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Glutamine synthetase.	0.528
FGF2	IL10	ENSCCAP00000011527	ENSCCAP00000034893	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Interleukin 10.	0.466
FGF2	KLF4	ENSCCAP00000011527	ENSCCAP00000033780	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Kruppel like factor 4.	0.511
FGF2	PIK3CB	ENSCCAP00000011527	ENSCCAP00000021785	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.405
FGF2	THBS1	ENSCCAP00000011527	ENSCCAP00000033479	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Thrombospondin 1.	0.474
GHRL	GHSR	ENSCCAP00000008994	ENSCCAP00000020603	Ghrelin and obestatin prepropeptide.	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	0.998
GHSR	GHRL	ENSCCAP00000020603	ENSCCAP00000008994	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Ghrelin and obestatin prepropeptide.	0.998
GLUL	FGF2	ENSCCAP00000014213	ENSCCAP00000011527	Glutamine synthetase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.528
IL10	FGF2	ENSCCAP00000034893	ENSCCAP00000011527	Interleukin 10.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.466
IL10	JAK1	ENSCCAP00000034893	ENSCCAP00000007943	Interleukin 10.	Tyrosine-protein kinase.	0.692
IL10	TJP1	ENSCCAP00000034893	ENSCCAP00000037184	Interleukin 10.	Tight junction protein 1; Belongs to the MAGUK family.	0.495
ITGA5	THBS1	ENSCCAP00000007111	ENSCCAP00000033479	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	Thrombospondin 1.	0.789
ITGA5	TNN	ENSCCAP00000007111	ENSCCAP00000034873	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	Tenascin N.	0.775
JAK1	IL10	ENSCCAP00000007943	ENSCCAP00000034893	Tyrosine-protein kinase.	Interleukin 10.	0.692
JAK1	PIK3CB	ENSCCAP00000007943	ENSCCAP00000021785	Tyrosine-protein kinase.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.946
KLF4	FGF2	ENSCCAP00000033780	ENSCCAP00000011527	Kruppel like factor 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.511
PDPK1	PIK3CB	ENSCCAP00000038488	ENSCCAP00000021785	3-phosphoinositide dependent protein kinase 1.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.959