STRINGSTRING
TGFB1 TGFB1 ZC3H10 ZC3H10 LIN28B LIN28B IL6 IL6 ZC3H12A ZC3H12A ZMPSTE24 ZMPSTE24 STAT3 STAT3 NCOR2 NCOR2 TNF TNF ENSCCAP00000022660 ENSCCAP00000022660 BCDIN3D BCDIN3D TERT TERT ESR1 ESR1 PPP3CA PPP3CA TP53 TP53 NCOR1 NCOR1 ENSCCAP00000031434 ENSCCAP00000031434 HNF1A HNF1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (314 aa)
ZC3H10Zinc finger CCCH-type containing 10. (434 aa)
LIN28BLin-28 homolog B. (262 aa)
IL6Interleukin 6. (212 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (598 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (479 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
NCOR2Nuclear receptor corepressor 2. (2513 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
ENSCCAP00000022660Uncharacterized protein. (404 aa)
BCDIN3DBCDIN3 domain containing RNA methyltransferase. (293 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1121 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
PPP3CASerine/threonine-protein phosphatase. (434 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (395 aa)
NCOR1SANT domain-containing protein. (2281 aa)
ENSCCAP00000031434Uncharacterized protein. (183 aa)
HNF1AHNF1 homeobox A. (661 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
Server load: low (16%) [HD]