STRINGSTRING
NOD2 NOD2 IL18 IL18 DOCK8 DOCK8 CCL21 CCL21 BMP4 BMP4 BCL10 BCL10 NOC2L NOC2L PRKCQ PRKCQ HCLS1 HCLS1 FOXP1 FOXP1 ORMDL3 ORMDL3 JAK3 JAK3 CD27 CD27 CCL19 CCL19 LOC108293547 LOC108293547 IL7R IL7R PDCD1 PDCD1 GAS6 GAS6 ADA ADA IDO1 IDO1 IRF7 IRF7 HIF1A HIF1A SLC46A2 SLC46A2 GHSR GHSR TSC22D3 TSC22D3 PTCRA PTCRA GPAM GPAM ARG2 ARG2 AURKB AURKB SLC39A10 SLC39A10 KITLG KITLG MERTK MERTK BCL6 BCL6 EFNA1 EFNA1 CD74 CD74 IL2 IL2 SELENOS SELENOS AXL AXL CCR7 CCR7 PIP PIP ENSCCAP00000012889 ENSCCAP00000012889 BCL2L1 BCL2L1 BCL3 BCL3 BCL11B BCL11B ST6GAL1 ST6GAL1 IRS2 IRS2 CXCL12 CXCL12 BCL2 BCL2 MIF MIF ENSCCAP00000005127 ENSCCAP00000005127 RAG1 RAG1 ST3GAL1 ST3GAL1 FADD FADD ITPKB ITPKB KIFAP3 KIFAP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2076 aa)
CCL21C-C motif chemokine ligand 21. (154 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
BCL10BCL10 immune signaling adaptor. (309 aa)
NOC2LNOC2 like nucleolar associated transcriptional repressor. (746 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (710 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (471 aa)
FOXP1Forkhead box P1. (693 aa)
ORMDL3ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
JAK3Tyrosine-protein kinase. (1115 aa)
CD27CD27 molecule. (260 aa)
CCL19C-C motif chemokine. (98 aa)
LOC108293547Uncharacterized protein. (773 aa)
IL7RInterleukin 7 receptor. (459 aa)
PDCD1Programmed cell death 1. (287 aa)
GAS6Growth arrest specific 6. (676 aa)
ADAA_deaminase domain-containing protein. (363 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (390 aa)
IRF7Interferon regulatory factor 7. (500 aa)
HIF1AUncharacterized protein. (848 aa)
SLC46A2Solute carrier family 46 member 2. (475 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
TSC22D3TSC22 domain family member 3. (198 aa)
PTCRAPre T cell antigen receptor alpha. (263 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
ARG2Arginase. (354 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
SLC39A10Solute carrier family 39 member 10. (831 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (268 aa)
MERTKReceptor protein-tyrosine kinase. (940 aa)
BCL6BCL6 transcription repressor. (706 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
CD74CD74 molecule. (308 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
SELENOSSelenoprotein S. (188 aa)
AXLAXL receptor tyrosine kinase. (896 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
PIPProlactin induced protein. (146 aa)
ENSCCAP00000012889Uncharacterized protein. (111 aa)
BCL2L1BCL2 like 1. (233 aa)
BCL3BCL3 transcription coactivator. (454 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (467 aa)
ST6GAL1ST6 beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (406 aa)
IRS2Insulin receptor substrate 2. (1361 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
BCL2BCL2 apoptosis regulator. (240 aa)
MIFUncharacterized protein. (115 aa)
ENSCCAP00000005127A_deaminase domain-containing protein. (260 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
ST3GAL1ST3 beta-galactoside alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (340 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (946 aa)
KIFAP3Kinesin associated protein 3. (799 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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