STRINGSTRING
PCSK6 PCSK6 FURIN FURIN SCUBE1 SCUBE1 EPHB1 EPHB1 C8A C8A NID2 NID2 NID1 NID1 SLIT3 SLIT3 ENSCCAP00000012723 ENSCCAP00000012723 SLIT1 SLIT1 EGFR EGFR FBLN5 FBLN5 EGFL7 EGFL7 LOC108316119 LOC108316119 INSR INSR SVEP1 SVEP1 CRELD1 CRELD1 FAT4 FAT4 EPHA7 EPHA7 CCN1 CCN1 EGFL6 EGFL6 DLL1 DLL1 LDLR LDLR IGFBPL1 IGFBPL1 UMOD UMOD SUSD1 SUSD1 JAG2 JAG2 THBD THBD RSPO4 RSPO4 FBLN2 FBLN2 CELSR2 CELSR2 EFEMP2 EFEMP2 RSPO2 RSPO2 THBS4 THBS4 DLL3 DLL3 EPHA2 EPHA2 PROS1 PROS1 JAG1 JAG1 C9 C9 CRB1 CRB1 UMODL1 UMODL1 LTBP1 LTBP1 EPHB4 EPHB4 CCN5 CCN5 SNED1 SNED1 LTBP2 LTBP2 IGFBP3 IGFBP3 EFEMP1 EFEMP1 TMEM67 TMEM67 EPHA5 EPHA5 DLL4 DLL4 FBN1 FBN1 MUC13 MUC13 LRP1B LRP1B CCN4 CCN4 KAZALD1 KAZALD1 IGFBP7 IGFBP7 FBLN1 FBLN1 DNER DNER FBN2 FBN2 IGF1R IGF1R RSPO3 RSPO3 PCSK5 PCSK5 HMCN2 HMCN2 LTBP3 LTBP3 MATN2 MATN2 NOTCH4 NOTCH4 KIAA1324 KIAA1324 MATN4 MATN4 KIAA1324L KIAA1324L IGFBP4 IGFBP4 VWCE VWCE LAMA2 LAMA2 HTRA1 HTRA1 ESM1 ESM1 ERBB2 ERBB2 IGFBP2 IGFBP2 MATN3 MATN3 CD248 CD248 FBN3 FBN3 NPNT NPNT NELL2 NELL2 CD93 CD93 FRAS1 FRAS1 SCUBE3 SCUBE3 LRP2 LRP2 PCSK4 PCSK4 ERBB3 ERBB3 CCN2 CCN2 NOTCH1 NOTCH1 VLDLR VLDLR CRIM1 CRIM1 SCARF2 SCARF2 LRP4 LRP4 BRINP3 BRINP3 CCN6 CCN6 NELL1 NELL1 IGFBP6 IGFBP6 ADGRE1 ADGRE1 IGFBP5 IGFBP5 IGFBP1 IGFBP1 BMP1 BMP1 INSRR INSRR EPHA1 EPHA1 RSPO1 RSPO1 ERBB4 ERBB4 GAS6 GAS6 MEGF6 MEGF6 EPHA6 EPHA6 CCN3 CCN3 CRELD2 CRELD2 SCUBE2 SCUBE2 LTBP4 LTBP4 EPHB2 EPHB2 NOTCH3 NOTCH3 ADGRE5 ADGRE5 LRP1 LRP1 HMCN1 HMCN1 HTRA3 HTRA3 EGF EGF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (956 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
SCUBE1Signal peptide, CUB domain and EGF like domain containing 1. (961 aa)
EPHB1EPH receptor B1. (984 aa)
C8AComplement C8 alpha chain. (587 aa)
NID2Nidogen 2. (1378 aa)
NID1Nidogen 1. (1193 aa)
SLIT3Slit guidance ligand 3. (1409 aa)
ENSCCAP00000012723Uncharacterized protein. (2489 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
FBLN5Fibulin 5. (489 aa)
EGFL7EGF like domain multiple 7. (273 aa)
LOC108316119Keratin 83; Belongs to the intermediate filament family. (493 aa)
INSRTyrosine-protein kinase receptor. (1352 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3570 aa)
CRELD1Cysteine rich with EGF like domains 1. (420 aa)
FAT4FAT atypical cadherin 4. (4983 aa)
EPHA7EPH receptor A7. (998 aa)
CCN1Cellular communication network factor 1. (381 aa)
EGFL6EGF like domain multiple 6. (555 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
LDLRLow density lipoprotein receptor. (934 aa)
IGFBPL1Insulin like growth factor binding protein like 1. (274 aa)
UMODUromodulin. (679 aa)
SUSD1Sushi domain containing 1. (720 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1274 aa)
THBDThrombomodulin. (588 aa)
RSPO4R-spondin 4. (234 aa)
FBLN2Fibulin 2. (1225 aa)
CELSR2Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2922 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (443 aa)
RSPO2R-spondin 2. (243 aa)
THBS4Thrombospondin 4. (961 aa)
DLL3Delta like canonical Notch ligand 3. (618 aa)
EPHA2EPH receptor A2. (976 aa)
PROS1Protein S. (676 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
C9Complement C9. (557 aa)
CRB1Crumbs cell polarity complex component 1. (1406 aa)
UMODL1Uromodulin like 1. (1443 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1719 aa)
EPHB4EPH receptor B4. (987 aa)
CCN5Cellular communication network factor 5. (250 aa)
SNED1Sushi, nidogen and EGF like domains 1. (1413 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1814 aa)
IGFBP3Insulin like growth factor binding protein 3. (291 aa)
EFEMP1EGF containing fibulin extracellular matrix protein 1. (493 aa)
TMEM67Transmembrane protein 67. (960 aa)
EPHA5EPH receptor A5. (1038 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
FBN1Fibrillin 1. (2872 aa)
MUC13Mucin 13, cell surface associated. (494 aa)
LRP1BLDL receptor related protein 1B. (4599 aa)
CCN4Cellular communication network factor 4. (367 aa)
KAZALD1Kazal type serine peptidase inhibitor domain 1. (301 aa)
IGFBP7Insulin like growth factor binding protein 7. (282 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (715 aa)
DNERDelta/notch like EGF repeat containing. (736 aa)
FBN2Fibrillin 2. (2912 aa)
IGF1RTyrosine-protein kinase receptor. (1285 aa)
RSPO3R-spondin 3. (292 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1859 aa)
HMCN2Hemicentin 2. (5005 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1300 aa)
MATN2Matrilin 2. (986 aa)
NOTCH4Notch receptor 4. (1993 aa)
KIAA1324KIAA1324. (927 aa)
MATN4Matrilin 4. (621 aa)
KIAA1324LKIAA1324 like. (1029 aa)
IGFBP4Insulin like growth factor binding protein 4. (258 aa)
VWCEVon Willebrand factor C and EGF domains. (955 aa)
LAMA2Laminin subunit alpha 2. (3052 aa)
HTRA1HtrA serine peptidase 1. (483 aa)
ESM1Endothelial cell specific molecule 1. (183 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
IGFBP2Insulin like growth factor binding protein 2. (317 aa)
MATN3Matrilin 3. (487 aa)
CD248CD248 molecule. (757 aa)
FBN3Fibrillin 3. (2809 aa)
NPNTNephronectin. (610 aa)
NELL2Neural EGFL like 2. (865 aa)
CD93CD93 molecule. (649 aa)
FRAS1Fraser extracellular matrix complex subunit 1. (4013 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (993 aa)
LRP2LDL receptor related protein 2. (4656 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (749 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1352 aa)
CCN2Cellular communication network factor 2. (349 aa)
NOTCH1Notch receptor 1. (2550 aa)
VLDLRVery low density lipoprotein receptor. (873 aa)
CRIM1Cysteine rich transmembrane BMP regulator 1. (1037 aa)
SCARF2Scavenger receptor class F member 2. (862 aa)
LRP4LDL receptor related protein 4. (1905 aa)
BRINP3BMP/retinoic acid inducible neural specific 3. (766 aa)
CCN6Cellular communication network factor 6. (372 aa)
NELL1Neural EGFL like 1. (810 aa)
IGFBP6Insulin like growth factor binding protein 6. (239 aa)
ADGRE1Adhesion G protein-coupled receptor E1; Belongs to the G-protein coupled receptor 2 family. (916 aa)
IGFBP5Insulin like growth factor binding protein 5. (273 aa)
IGFBP1Uncharacterized protein. (234 aa)
BMP1Metalloendopeptidase. (987 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
EPHA1EPH receptor A1. (976 aa)
RSPO1R-spondin 1. (263 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
GAS6Growth arrest specific 6. (676 aa)
MEGF6Multiple EGF like domains 6. (1497 aa)
EPHA6EPH receptor A6. (1130 aa)
CCN3Cellular communication network factor 3. (357 aa)
CRELD2Cysteine rich with EGF like domains 2. (408 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (997 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1624 aa)
EPHB2EPH receptor B2. (1103 aa)
NOTCH3Notch receptor 3. (2321 aa)
ADGRE5Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family. (841 aa)
LRP1LDL receptor related protein 1. (4544 aa)
HMCN1Hemicentin 1. (5635 aa)
HTRA3HtrA serine peptidase 3. (453 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.