Groups of genes that are frequently observed in each other's genomic neighborhood.
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Experiments
Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
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Fusion
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLXND1
Plexin D1. (1924 aa)
PLXNA3
Plexin A3. (1871 aa)
PLXNA2
Plexin A2. (1905 aa)
PLXNA4
Plexin A4. (1894 aa)
PLXNB3
Plexin B3. (1952 aa)
PLXNB1
Plexin B1. (2137 aa)
PLXNA1
Plexin A1. (1904 aa)
PLXNB2
Plexin B2. (1839 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516 Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin