STRINGSTRING
CDK4 CDK4 LOC108316501 LOC108316501 ENSCCAP00000000393 ENSCCAP00000000393 HIST1H2BO HIST1H2BO ENSCCAP00000000595 ENSCCAP00000000595 ENSCCAP00000000717 ENSCCAP00000000717 LOC108310203 LOC108310203 ENSCCAP00000000930 ENSCCAP00000000930 LOC108287016 LOC108287016 H2AC20 H2AC20 LOC108312590 LOC108312590 ZP3 ZP3 B4GALT1 B4GALT1 UBE2I UBE2I RPA1 RPA1 LOC108287040 LOC108287040 HIST1H4E HIST1H4E H2AX H2AX LOC108306916 LOC108306916 HIST2H3C HIST2H3C MRE11 MRE11 LOC108287013 LOC108287013 H2AC7 H2AC7 STAG2 STAG2 H2BU1 H2BU1 H2BC3 H2BC3 LOC108306905 LOC108306905 ENSCCAP00000002836 ENSCCAP00000002836 LOC108287010 LOC108287010 LOC108297261 LOC108297261 SYCP2 SYCP2 HVCN1 HVCN1 LOC108287012 LOC108287012 ENSCCAP00000003491 ENSCCAP00000003491 ENSCCAP00000003596 ENSCCAP00000003596 ENSCCAP00000003603 ENSCCAP00000003603 LOC108285395 LOC108285395 H2AJ H2AJ RBBP8 RBBP8 ENSCCAP00000004129 ENSCCAP00000004129 H2BC1 H2BC1 ENSCCAP00000004623 ENSCCAP00000004623 ENSCCAP00000004759 ENSCCAP00000004759 MLH1 MLH1 ENSCCAP00000004930 ENSCCAP00000004930 LOC108311240 LOC108311240 LOC108304268 LOC108304268 ENSCCAP00000005142 ENSCCAP00000005142 SYCP3 SYCP3 LOC108297260 LOC108297260 H3C6 H3C6 STAG3 STAG3 LOC108316498 LOC108316498 IZUMO4 IZUMO4 LOC108301415 LOC108301415 LOC108317468 LOC108317468 ACR ACR LOC108294600 LOC108294600 LMNB1 LMNB1 SUN1 SUN1 LOC108291174 LOC108291174 H3F3A H3F3A FKBP6 FKBP6 DMC1 DMC1 RAD51 RAD51 ENSCCAP00000009590 ENSCCAP00000009590 SPO11 SPO11 SPAG4 SPAG4 TERF1 TERF1 BLM BLM ACD ACD LMNA LMNA SPAM1 SPAM1 ADAM32 ADAM32 REC8 REC8 CATSPER3 CATSPER3 ENSCCAP00000012006 ENSCCAP00000012006 LOC108317875 LOC108317875 TERF2IP TERF2IP FAM9B FAM9B RPA3 RPA3 TEX12 TEX12 ENSCCAP00000015138 ENSCCAP00000015138 ADAM2 ADAM2 ENSCCAP00000016251 ENSCCAP00000016251 IZUMO2 IZUMO2 CATSPER2 CATSPER2 H2AZ2 H2AZ2 LOC108287552 LOC108287552 BRCA1 BRCA1 CATSPERB CATSPERB SYNE2 SYNE2 SUN3 SUN3 ENSCCAP00000018777 ENSCCAP00000018777 SYCP2L SYCP2L SYCE1 SYCE1 CATSPERD CATSPERD CDK2 CDK2 ATM ATM ZP2 ZP2 ENSCCAP00000040419 ENSCCAP00000040419 STAG1 STAG1 SMC1B SMC1B IZUMO3 IZUMO3 ATR ATR LOC108313247 LOC108313247 RAD50 RAD50 ENSCCAP00000038982 ENSCCAP00000038982 ZP4 ZP4 TERF2 TERF2 ENSCCAP00000037034 ENSCCAP00000037034 KCNU1 KCNU1 ADAM18 ADAM18 CD9 CD9 POT1 POT1 TINF2 TINF2 ENSCCAP00000034806 ENSCCAP00000034806 SYNE1 SYNE1 ENSCCAP00000034559 ENSCCAP00000034559 SYCE3 SYCE3 ENSCCAP00000034488 ENSCCAP00000034488 RAD21 RAD21 SMC3 SMC3 PSMC3IP PSMC3IP DIDO1 DIDO1 MSH4 MSH4 SUN5 SUN5 ENSCCAP00000033351 ENSCCAP00000033351 SYCP1 SYCP1 MSH5 MSH5 OVGP1 OVGP1 SYCE2 SYCE2 BRCA2 BRCA2 ENSCCAP00000031654 ENSCCAP00000031654 ENSCCAP00000031489 ENSCCAP00000031489 ENSCCAP00000031460 ENSCCAP00000031460 NBN NBN SMC1A SMC1A MND1 MND1 RAD51C RAD51C ENSCCAP00000030012 ENSCCAP00000030012 ENSCCAP00000029615 ENSCCAP00000029615 ENSCCAP00000029318 ENSCCAP00000029318 ENSCCAP00000029008 ENSCCAP00000029008 ENSCCAP00000028779 ENSCCAP00000028779 H3F3B H3F3B TMEM238 TMEM238 ENSCCAP00000028540 ENSCCAP00000028540 MLH3 MLH3 KCNT2 KCNT2 LOC108304334 LOC108304334 ENSCCAP00000022407 ENSCCAP00000022407 ENSCCAP00000022747 ENSCCAP00000022747 HSPA2 HSPA2 ENSCCAP00000024326 ENSCCAP00000024326 SUN2 SUN2 TOP3A TOP3A ENSCCAP00000025584 ENSCCAP00000025584 TEX15 TEX15 ENSCCAP00000026582 ENSCCAP00000026582 LOC108306685 LOC108306685 CATSPER4 CATSPER4 ENSCCAP00000027036 ENSCCAP00000027036 LOC108298786 LOC108298786 LOC108298788 LOC108298788 ENSCCAP00000027473 ENSCCAP00000027473 IZUMO1 IZUMO1 LOC108298207 LOC108298207 LOC108315074 LOC108315074 CATSPERG CATSPERG ENSCCAP00000028238 ENSCCAP00000028238 CATSPER1 CATSPER1 LOC108298787 LOC108298787
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDK4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
LOC108316501Histone H3; Belongs to the histone H3 family. (136 aa)
ENSCCAP00000000393Uncharacterized protein. (145 aa)
HIST1H2BOHistone H2B; Belongs to the histone H2B family. (126 aa)
ENSCCAP00000000595Histone H2A; Belongs to the histone H2A family. (110 aa)
ENSCCAP00000000717Histone H3; Belongs to the histone H3 family. (136 aa)
LOC108310203Uncharacterized protein. (729 aa)
ENSCCAP00000000930annotation not available (136 aa)
LOC108287016Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC108312590Histone H2B; Belongs to the histone H2B family. (126 aa)
ZP3ZP domain-containing protein. (428 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (400 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa)
LOC108287040Histone domain-containing protein; Belongs to the histone H2B family. (127 aa)
HIST1H4EHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
LOC108306916Histone H2B; Belongs to the histone H2B family. (126 aa)
HIST2H3CHistone H3; Belongs to the histone H3 family. (136 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (709 aa)
LOC108287013Histone H2A; Belongs to the histone H2A family. (130 aa)
H2AC7Histone H2A; Belongs to the histone H2A family. (130 aa)
STAG2Stromal antigen 2. (1242 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC108306905Histone H3; Belongs to the histone H3 family. (136 aa)
ENSCCAP00000002836annotation not available (103 aa)
LOC108287010Histone H3.1. (136 aa)
LOC108297261Histone H4. (103 aa)
SYCP2Synaptonemal complex protein 2. (1511 aa)
HVCN1Hydrogen voltage gated channel 1. (276 aa)
LOC108287012Histone H2A type 1. (130 aa)
ENSCCAP00000003491Histone H3; Belongs to the histone H3 family. (136 aa)
ENSCCAP00000003596annotation not available (103 aa)
ENSCCAP00000003603annotation not available (136 aa)
LOC108285395Histone domain-containing protein. (136 aa)
H2AJHistone H2A; Belongs to the histone H2A family. (129 aa)
RBBP8RB binding protein 8, endonuclease. (899 aa)
ENSCCAP00000004129annotation not available (103 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
ENSCCAP00000004623annotation not available (103 aa)
ENSCCAP00000004759annotation not available (136 aa)
MLH1MutL homolog 1. (757 aa)
ENSCCAP00000004930annotation not available (103 aa)
LOC108311240Histone H3; Belongs to the histone H3 family. (136 aa)
LOC108304268Histone H4. (103 aa)
ENSCCAP00000005142annotation not available (103 aa)
SYCP3Cor1 domain-containing protein. (236 aa)
LOC108297260Histone H2B type 1. (126 aa)
H3C6H3 clustered histone 6. (136 aa)
STAG3Stromal antigen 3. (1247 aa)
LOC108316498Histone H2B; Belongs to the histone H2B family. (126 aa)
IZUMO4IZUMO family member 4. (232 aa)
LOC108301415Uncharacterized protein. (111 aa)
LOC108317468Histone H3; Belongs to the histone H3 family. (136 aa)
ACRAcrosin; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome. (417 aa)
LOC108294600Uncharacterized protein. (690 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (586 aa)
SUN1Sad1 and UNC84 domain containing 1. (813 aa)
LOC108291174Histone H2A; Belongs to the histone H2A family. (128 aa)
H3F3AHistone H3; Belongs to the histone H3 family. (136 aa)
FKBP6Peptidylprolyl isomerase. (264 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (311 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
ENSCCAP00000009590Rad21_Rec8 domain-containing protein. (546 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (396 aa)
SPAG4Sperm associated antigen 4. (438 aa)
TERF1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (376 aa)
BLMBLM RecQ like helicase. (1401 aa)
ACDACD shelterin complex subunit and telomerase recruitment factor. (509 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (677 aa)
SPAM1Hyaluronidase. (509 aa)
ADAM32ADAM metallopeptidase domain 32. (787 aa)
REC8REC8 meiotic recombination protein. (548 aa)
CATSPER3Cation channel sperm associated 3. (396 aa)
ENSCCAP00000012006UBIQUITIN_CONJUGAT_2 domain-containing protein. (193 aa)
LOC108317875RECA_2 domain-containing protein. (351 aa)
TERF2IPTERF2 interacting protein. (399 aa)
FAM9BFamily with sequence similarity 9 member B. (187 aa)
RPA3Uncharacterized protein. (121 aa)
TEX12Testis expressed 12. (123 aa)
ENSCCAP00000015138TRF domain-containing protein. (250 aa)
ADAM2ADAM metallopeptidase domain 2. (732 aa)
ENSCCAP00000016251Uncharacterized protein. (107 aa)
IZUMO2IZUMO family member 2. (221 aa)
CATSPER2Ion_trans domain-containing protein. (530 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (128 aa)
LOC108287552Cor1 domain-containing protein. (217 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1830 aa)
CATSPERBCation channel sperm associated auxiliary subunit beta. (1116 aa)
SYNE2Spectrin repeat containing nuclear envelope protein 2. (6913 aa)
SUN3Sad1 and UNC84 domain containing 3. (357 aa)
ENSCCAP00000018777Histone H2A; Belongs to the histone H2A family. (121 aa)
SYCP2LSynaptonemal complex protein 2 like. (742 aa)
SYCE1Synaptonemal complex central element protein 1. (333 aa)
CATSPERDCation channel sperm associated auxiliary subunit delta. (605 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3000 aa)
ZP2Zona pellucida glycoprotein 2. (747 aa)
ENSCCAP00000040419Histone H2B; Belongs to the histone H2B family. (129 aa)
STAG1Stromal antigen 1. (1267 aa)
SMC1BStructural maintenance of chromosomes protein. (1235 aa)
IZUMO3IZUMO family member 3. (240 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa)
LOC108313247Protein kinase domain-containing protein. (276 aa)
RAD50Zinc-hook domain-containing protein. (1312 aa)
ENSCCAP00000038982Uncharacterized protein. (128 aa)
ZP4Zona pellucida glycoprotein 4. (540 aa)
TERF2Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (527 aa)
ENSCCAP00000037034Histone domain-containing protein. (122 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1126 aa)
ADAM18ADAM metallopeptidase domain 18. (738 aa)
CD9Tetraspanin. (228 aa)
POT1Protection of telomeres 1. (666 aa)
TINF2TERF1 interacting nuclear factor 2. (447 aa)
ENSCCAP00000034806Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (260 aa)
SYNE1Spectrin repeat containing nuclear envelope protein 1. (8797 aa)
ENSCCAP00000034559Mnd1 domain-containing protein. (127 aa)
SYCE3Synaptonemal complex central element protein 3. (88 aa)
ENSCCAP00000034488Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (91 aa)
RAD21RAD21 cohesin complex component. (605 aa)
SMC3Structural maintenance of chromosomes protein. (1215 aa)
PSMC3IPPSMC3 interacting protein. (217 aa)
DIDO1Death inducer-obliterator 1. (2218 aa)
MSH4DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (870 aa)
SUN5Sad1 and UNC84 domain containing 5. (379 aa)
ENSCCAP00000033351annotation not available (131 aa)
SYCP1Synaptonemal complex protein 1. (976 aa)
MSH5DNA_MISMATCH_REPAIR_2 domain-containing protein. (833 aa)
OVGP1Oviductal glycoprotein 1; Belongs to the glycosyl hydrolase 18 family. (681 aa)
SYCE2Synaptonemal complex central element protein 2. (178 aa)
BRCA2BRCA2 DNA repair associated. (3397 aa)
ENSCCAP00000031654Histone H2B; Belongs to the histone H2B family. (142 aa)
ENSCCAP00000031489HTH myb-type domain-containing protein. (287 aa)
ENSCCAP00000031460Protein kinase domain-containing protein. (272 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (753 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
MND1Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (207 aa)
RAD51CRECA_2 domain-containing protein. (352 aa)
ENSCCAP00000030012Protein kinase domain-containing protein. (266 aa)
ENSCCAP00000029615Mnd1 domain-containing protein. (155 aa)
ENSCCAP00000029318Histone H2A; Belongs to the histone H2A family. (112 aa)
ENSCCAP00000029008annotation not available (136 aa)
ENSCCAP00000028779UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (186 aa)
H3F3BH3 histone, family 3B. (136 aa)
TMEM238Transmembrane protein 238. (176 aa)
ENSCCAP00000028540annotation not available (136 aa)
MLH3MutL homolog 3. (1456 aa)
KCNT2Potassium sodium-activated channel subfamily T member 2. (1135 aa)
LOC108304334Protein kinase domain-containing protein. (342 aa)
ENSCCAP00000022407Uncharacterized protein. (67 aa)
ENSCCAP00000022747Uncharacterized protein. (116 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (601 aa)
ENSCCAP00000024326Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (131 aa)
SUN2Sad1 and UNC84 domain containing 2. (725 aa)
TOP3ADNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1001 aa)
ENSCCAP00000025584Histone H2A; Belongs to the histone H2A family. (130 aa)
TEX15Testis expressed 15, meiosis and synapsis associated. (3175 aa)
ENSCCAP00000026582Cor1 domain-containing protein. (249 aa)
LOC108306685Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (188 aa)
CATSPER4Cation channel sperm associated 4. (472 aa)
ENSCCAP00000027036annotation not available (136 aa)
LOC108298786Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC108298788Histone H4. (103 aa)
ENSCCAP00000027473annotation not available (136 aa)
IZUMO1Izumo sperm-egg fusion 1. (323 aa)
LOC108298207Histone H4. (103 aa)
LOC108315074Histone H3; Belongs to the histone H3 family. (136 aa)
CATSPERGCation channel sperm associated auxiliary subunit gamma. (1160 aa)
ENSCCAP00000028238Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (422 aa)
CATSPER1Cation channel sperm associated 1. (736 aa)
LOC108298787Histone H4. (103 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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