STRINGSTRING
FBXW11 FBXW11 ENSCCAP00000033921 ENSCCAP00000033921 NOD2 NOD2 NFKBIA NFKBIA FOSL2 FOSL2 MAPK10 MAPK10 UBA52 UBA52 CREM CREM FGG FGG TLR4 TLR4 ENSCCAP00000004857 ENSCCAP00000004857 SOCS1 SOCS1 LOC108290290 LOC108290290 LRRC14 LRRC14 LOC108313418 LOC108313418 LOC108306503 LOC108306503 MEF2C MEF2C FGB FGB ENSCCAP00000003376 ENSCCAP00000003376 NKIRAS2 NKIRAS2 LOC108290397 LOC108290397 MAP3K1 MAP3K1 S100B S100B TAB2 TAB2 JUND JUND N4BP1 N4BP1 BTK BTK VWC2 VWC2 ENSCCAP00000001605 ENSCCAP00000001605 TRAF6 TRAF6 LOC108315963 LOC108315963 NLRP6 NLRP6 TAB3 TAB3 RELCH RELCH ENSCCAP00000000501 ENSCCAP00000000501 KHNYN KHNYN AGER AGER ENSCCAP00000032435 ENSCCAP00000032435 ATF7 ATF7 DUSP3 DUSP3 UBE2N UBE2N PELI1 PELI1 ENSCCAP00000031656 ENSCCAP00000031656 NFKB1 NFKB1 CHUK CHUK PELI3 PELI3 DUSP7 DUSP7 ENSCCAP00000030160 ENSCCAP00000030160 CD36 CD36 TP53 TP53 PPP2CB PPP2CB LY96 LY96 NFKBIB NFKBIB RPS6KA2 RPS6KA2 LOC108295752 LOC108295752 MAP2K4 MAP2K4 USP14 USP14 SKP1 SKP1 PPP2R5D PPP2R5D ENSCCAP00000008478 ENSCCAP00000008478 RELA RELA LRRC31 LRRC31 NLRC5 NLRC5 MAPK15 MAPK15 CD14 CD14 ELK1 ELK1 IKBKB IKBKB NKIRAS1 NKIRAS1 ENSCCAP00000011005 ENSCCAP00000011005 LRRC74B LRRC74B PPP4R1 PPP4R1 IRAK1 IRAK1 LOC108302273 LOC108302273 MAPKAPK3 MAPKAPK3 TAB1 TAB1 NOD1 NOD1 LOC108282680 LOC108282680 LOC108302272 LOC108302272 CREB1 CREB1 CUL1 CUL1 LOC108302271 LOC108302271 MAPK1 MAPK1 ENSCCAP00000014916 ENSCCAP00000014916 S100A12 S100A12 PPP2R1A PPP2R1A PPP2CA PPP2CA LOC108309935 LOC108309935 ALPK1 ALPK1 MYD88 MYD88 IRAK2 IRAK2 SIGIRR SIGIRR IRAK3 IRAK3 FOS FOS IRAK4 IRAK4 CCDC71L CCDC71L MAP2K7 MAP2K7 ATF1 ATF1 TNIP2 TNIP2 MAP2K3 MAP2K3 ENSCCAP00000017896 ENSCCAP00000017896 ENSCCAP00000017906 ENSCCAP00000017906 MAPK7 MAPK7 MAP3K7 MAP3K7 MAP2K6 MAP2K6 S100A1 S100A1 TRAF2 TRAF2 MAPKAPK2 MAPKAPK2 PELI2 PELI2 HMGB1 HMGB1 RPS6KA5 RPS6KA5 ENSCCAP00000021037 ENSCCAP00000021037 LOC108310759 LOC108310759 CASP8 CASP8 ENSCCAP00000021490 ENSCCAP00000021490 S100A9 S100A9 CREB5 CREB5 BTRC BTRC APP APP S100A8 S100A8 MAP3K20 MAP3K20 LRRC74A LRRC74A IKBKG IKBKG NLRP13 NLRP13 ECSIT ECSIT ENSCCAP00000025562 ENSCCAP00000025562 VRK3 VRK3 RIPK2 RIPK2 DUSP6 DUSP6 LRRC34 LRRC34 PPP2R1B PPP2R1B MAPK14 MAPK14 ENSCCAP00000026853 ENSCCAP00000026853 LRRC45 LRRC45 LOC108285114 LOC108285114 ENSCCAP00000040563 ENSCCAP00000040563 MAPK9 MAPK9 MAPK11 MAPK11 PPP4R4 PPP4R4 KXD1 KXD1 RPS27A RPS27A ENSCCAP00000039561 ENSCCAP00000039561 LRRC71 LRRC71 LOC108285592 LOC108285592 MAP3K8 MAP3K8 ENSCCAP00000038324 ENSCCAP00000038324 RPS6KA1 RPS6KA1 NLRP9 NLRP9 LOC108306798 LOC108306798 NFKB2 NFKB2 DUSP4 DUSP4 RPS6KA3 RPS6KA3 MAPK3 MAPK3 NLRX1 NLRX1 MEF2A MEF2A TONSL TONSL ATF2 ATF2 TLR2 TLR2 FNBP4 FNBP4 TIRAP TIRAP MAPK8 MAPK8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FBXW11F-box and WD repeat domain containing 11. (542 aa)
ENSCCAP00000033921Uncharacterized protein; Belongs to the SKP1 family. (162 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
NFKBIANFKB inhibitor alpha. (310 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (326 aa)
MAPK10Mitogen-activated protein kinase. (538 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
CREMcAMP responsive element modulator. (347 aa)
FGGFibrinogen gamma chain. (437 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (832 aa)
ENSCCAP00000004857Uncharacterized protein. (386 aa)
SOCS1Suppressor of cytokine signaling 1. (213 aa)
LOC108290290HMG box domain-containing protein. (132 aa)
LRRC14Leucine rich repeat containing 14. (493 aa)
LOC108313418UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
LOC108306503Ubiquitin-like domain-containing protein. (156 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
FGBFibrinogen beta chain. (491 aa)
ENSCCAP00000003376Protein kinase domain-containing protein. (184 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (230 aa)
LOC108290397Ubiquitin-like domain-containing protein. (156 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1508 aa)
S100BS_100 domain-containing protein; Belongs to the S-100 family. (93 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (350 aa)
N4BP1NEDD4 binding protein 1. (896 aa)
BTKTyrosine-protein kinase. (598 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
ENSCCAP00000001605Uncharacterized protein; Belongs to the SKP1 family. (164 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
LOC108315963Ubiquitin-like domain-containing protein. (156 aa)
NLRP6NLR family pyrin domain containing 6. (892 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa)
ENSCCAP00000000501UBIQUITIN_CONJUGAT_2 domain-containing protein. (114 aa)
KHNYNKH and NYN domain containing. (674 aa)
AGERAdvanced glycosylation end-product specific receptor. (403 aa)
ENSCCAP00000032435Uncharacterized protein. (154 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
ENSCCAP00000031656Fib_alpha domain-containing protein. (276 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (761 aa)
PELI3E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (469 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)
ENSCCAP00000030160Uncharacterized protein. (185 aa)
CD36CD36 molecule; Belongs to the CD36 family. (476 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (395 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
LY96Lymphocyte antigen 96. (160 aa)
NFKBIBNFKB inhibitor beta. (394 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
LOC108295752UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa)
MAP2K4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (410 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (492 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (128 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (600 aa)
ENSCCAP00000008478UBIQUITIN_CONJUGAT_2 domain-containing protein. (146 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
LRRC31Leucine rich repeat containing 31. (552 aa)
NLRC5NLR family CARD domain containing 5. (1868 aa)
MAPK15Mitogen-activated protein kinase. (547 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa)
ELK1ETS transcription factor ELK1. (428 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (111 aa)
ENSCCAP00000011005Ubiquitin-like domain-containing protein. (127 aa)
LRRC74BLeucine rich repeat containing 74B. (392 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (754 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (712 aa)
LOC108302273Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (120 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (427 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (505 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
LOC108282680Protein kinase domain-containing protein. (245 aa)
LOC108302272Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (120 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
LOC108302271Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (130 aa)
MAPK1Mitogen-activated protein kinase. (366 aa)
ENSCCAP00000014916UBIQUITIN_CONJUGAT_2 domain-containing protein. (133 aa)
S100A12S100 calcium binding protein A12; Belongs to the S-100 family. (92 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
LOC108309935WRNPLPNID domain-containing protein. (954 aa)
ALPK1Alpha kinase 1. (1241 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (626 aa)
SIGIRRSingle Ig and TIR domain containing. (370 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (596 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
CCDC71LUncharacterized protein. (293 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (435 aa)
ATF1Activating transcription factor 1. (270 aa)
TNIP2TNFAIP3 interacting protein 2. (322 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (392 aa)
ENSCCAP00000017896SER_THR_PHOSPHATASE domain-containing protein. (233 aa)
ENSCCAP00000017906Uncharacterized protein. (188 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (816 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
S100A1Protein S100; Belongs to the S-100 family. (146 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (401 aa)
PELI2Pellino E3 ubiquitin protein ligase family member 2. (403 aa)
HMGB1Uncharacterized protein. (187 aa)
RPS6KA5Ribosomal protein S6 kinase. (800 aa)
ENSCCAP00000021037Ubiquitin-like domain-containing protein. (118 aa)
LOC108310759UBIQUITIN_CONJUGAT_2 domain-containing protein. (87 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (522 aa)
ENSCCAP00000021490WD_REPEATS_REGION domain-containing protein. (470 aa)
S100A9S100 calcium binding protein A9; Belongs to the S-100 family. (110 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (600 aa)
APPAmyloid beta precursor protein. (770 aa)
S100A8Protein S100; Belongs to the S-100 family. (89 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
LRRC74ALeucine rich repeat containing 74A. (451 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (486 aa)
NLRP13NLR family pyrin domain containing 13. (1043 aa)
ECSITECSIT signalling integrator. (429 aa)
ENSCCAP00000025562Uncharacterized protein. (88 aa)
VRK3VRK serine/threonine kinase 3. (472 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (368 aa)
LRRC34Leucine rich repeat containing 34. (428 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (604 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ENSCCAP00000026853Ubiquitin-like domain-containing protein. (107 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
LOC108285114Ubiquitin-like domain-containing protein. (156 aa)
ENSCCAP00000040563Uncharacterized protein; Belongs to the SKP1 family. (155 aa)
MAPK9Mitogen-activated protein kinase. (392 aa)
MAPK11Mitogen-activated protein kinase. (368 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (873 aa)
KXD1KxDL motif containing 1. (194 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSCCAP00000039561UBIQUITIN_CONJUGAT_2 domain-containing protein. (135 aa)
LRRC71Leucine rich repeat containing 71. (559 aa)
LOC108285592UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (379 aa)
ENSCCAP00000038324Ubiquitin-like domain-containing protein. (117 aa)
RPS6KA1Ribosomal protein S6 kinase. (729 aa)
NLRP9NLR family pyrin domain containing 9. (934 aa)
LOC108306798Uncharacterized protein. (188 aa)
NFKB2Nuclear factor kappa B subunit 2. (900 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
RPS6KA3Non-specific serine/threonine protein kinase. (693 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
NLRX1NLR family member X1. (975 aa)
MEF2AMyocyte enhancer factor 2A. (502 aa)
TONSLTonsoku like, DNA repair protein. (1375 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
TLR2Toll-like receptor. (817 aa)
FNBP4Formin binding protein 4. (887 aa)
TIRAPTIR domain containing adaptor protein. (244 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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