STRINGSTRING
TNFRSF10A TNFRSF10A TNFRSF10B TNFRSF10B TRADD TRADD FAS FAS TRAF2 TRAF2 CASP8 CASP8 FADD FADD FASLG FASLG CFLAR CFLAR TNFSF10 TNFSF10 RIPK1 RIPK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNFRSF10ATNF receptor superfamily member 10a. (419 aa)
TNFRSF10BTNF receptor superfamily member 10b. (443 aa)
TRADDTNFRSF1A associated via death domain. (312 aa)
FASFas cell surface death receptor. (317 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (522 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (281 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (281 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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