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WDTC1 WDTC1 KYAT1 KYAT1 KATNAL2 KATNAL2 ACAD10 ACAD10 DLST DLST IL4I1 IL4I1 ECHS1 ECHS1 GCDH GCDH ENSCCAP00000020403 ENSCCAP00000020403 LOC108315736 LOC108315736 LOC108305144 LOC108305144 KYNU KYNU AOC1 AOC1 IDO1 IDO1 INMT INMT AADAT AADAT DDC DDC AFMID AFMID ASMTL ASMTL ALDH7A1 ALDH7A1 DHTKD1 DHTKD1 ALDH8A1 ALDH8A1 ACMSD ACMSD EHHADH EHHADH KYAT3 KYAT3 ALDH2 ALDH2 CAT CAT GTPBP1 GTPBP1 ACAT2 ACAT2 ALDH9A1 ALDH9A1 TDO2 TDO2 TPH2 TPH2 IDO2 IDO2 KMO KMO HADH HADH MAOA MAOA FIGNL2 FIGNL2 ALDH1B1 ALDH1B1 CYP1B1 CYP1B1 ASMT ASMT ALDH16A1 ALDH16A1 ALDH3A2 ALDH3A2 ACAD11 ACAD11 CYP1A1 CYP1A1 HAAO HAAO CARTPT CARTPT LOC108301874 LOC108301874 LOC108291913 LOC108291913 FIGN FIGN AANAT AANAT TTLL12 TTLL12 SPAST SPAST ACAT1 ACAT1 TPH1 TPH1 MAOB MAOB HADHA HADHA AOX1 AOX1 DLD DLD
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WDTC1WD and tetratricopeptide repeats 1. (693 aa)
KYAT1Aminotran_1_2 domain-containing protein. (456 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (538 aa)
ACAD10Acyl-CoA dehydrogenase family member 10. (1089 aa)
DLSTUncharacterized protein. (457 aa)
IL4I1Amine oxidase. (590 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa)
GCDHGlutaryl-CoA dehydrogenase. (438 aa)
ENSCCAP00000020403Lipoyl-binding domain-containing protein. (439 aa)
LOC108315736Uncharacterized protein. (1349 aa)
LOC108305144Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (706 aa)
KYNUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (465 aa)
AOC1Amine oxidase. (751 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (390 aa)
INMTUncharacterized protein. (233 aa)
AADATAminoadipate aminotransferase. (425 aa)
DDCDopa decarboxylase. (480 aa)
AFMIDKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (305 aa)
ASMTLAcetylserotonin O-methyltransferase like. (619 aa)
ALDH7A1Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (554 aa)
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (919 aa)
ALDH8A1Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (441 aa)
ACMSD2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
KYAT3Kynurenine aminotransferase 3. (481 aa)
ALDH2Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (517 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
GTPBP1GTP binding protein 1. (676 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
ALDH9A1Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (457 aa)
TDO2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)
TPH2Tryptophan hydroxylase 2. (490 aa)
IDO2Indoleamine 2,3-dioxygenase 2. (420 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (508 aa)
HADHHydroxyacyl-CoA dehydrogenase. (317 aa)
MAOAAmine oxidase. (527 aa)
FIGNL2Fidgetin like 2. (653 aa)
ALDH1B1Aldehyde dehydrogenase 1 family member B1; Belongs to the aldehyde dehydrogenase family. (517 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
ASMTAcetylserotonin O-methyltransferase. (440 aa)
ALDH16A1Aldehyde dehydrogenase family 16 member A1. (802 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (508 aa)
ACAD11Acyl-CoA dehydrogenase family member 11. (781 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (512 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa)
CARTPTCART prepropeptide. (116 aa)
LOC108301874Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (481 aa)
LOC108291913Lipoyl-binding domain-containing protein. (440 aa)
FIGNFidgetin, microtubule severing factor; Belongs to the AAA ATPase family. (759 aa)
AANATAralkylamine N-acetyltransferase. (252 aa)
TTLL12Tubulin tyrosine ligase like 12. (645 aa)
SPASTSpastin; Belongs to the AAA ATPase family. (590 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
TPH1Tryptophan hydroxylase 1. (444 aa)
MAOBAmine oxidase. (520 aa)
HADHAUncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (773 aa)
AOX1Aldehyde oxidase 1. (1321 aa)
DLDDihydrolipoyl dehydrogenase. (509 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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