STRINGSTRING
MAPK10 MAPK10 PIK3R1 PIK3R1 LOC108290468 LOC108290468 E2F2 E2F2 GNAS GNAS JAG2 JAG2 CARM1 CARM1 BCL2 BCL2 CDKN2C CDKN2C RPS6KB1 RPS6KB1 PPP1R14B PPP1R14B LOC108297870 LOC108297870 MAP2K2 MAP2K2 NCOA3 NCOA3 RB1 RB1 ADCY4 ADCY4 ENSCCAP00000003376 ENSCCAP00000003376 DLL3 DLL3 BAD BAD MDM2 MDM2 JAG1 JAG1 LOC108298339 LOC108298339 MED1 MED1 LOC108300898 LOC108300898 SP1 SP1 MAPK9 MAPK9 MAPK11 MAPK11 LOC108313247 LOC108313247 NOTCH3 NOTCH3 ENSCCAP00000038982 ENSCCAP00000038982 MMP9 MMP9 CSDE1 CSDE1 LOC108309036 LOC108309036 MAPK3 MAPK3 IGF1 IGF1 PIK3R2 PIK3R2 CDKN1B CDKN1B CCDC170 CCDC170 ARAF ARAF CEP152 CEP152 ENSCCAP00000034806 ENSCCAP00000034806 MAPK8 MAPK8 ENSCCAP00000034704 ENSCCAP00000034704 AKT1 AKT1 SHC1 SHC1 NOTCH1 NOTCH1 PRKACA PRKACA LOC108290469 LOC108290469 CDKN2A CDKN2A ADCY1 ADCY1 PTRHD1 PTRHD1 ENSCCAP00000031460 ENSCCAP00000031460 HBEGF HBEGF ENSCCAP00000031241 ENSCCAP00000031241 NCOR1 NCOR1 ENSCCAP00000030012 ENSCCAP00000030012 ERBB2 ERBB2 TP53 TP53 ADCY5 ADCY5 CDK4 CDK4 GPER1 GPER1 KRAS KRAS GRB2 GRB2 E2F1 E2F1 MAPK12 MAPK12 HRAS HRAS BRAF BRAF MAPK14 MAPK14 SHC2 SHC2 ESR1 ESR1 ENSCCAP00000026158 ENSCCAP00000026158 NRAS NRAS IGF1R IGF1R LOC108285920 LOC108285920 ADCY8 ADCY8 ESR2 ESR2 ENSCCAP00000022660 ENSCCAP00000022660 LOC108304334 LOC108304334 PIK3CB PIK3CB RPS6KB2 RPS6KB2 MTOR MTOR CCND1 CCND1 ADCY2 ADCY2 BIK BIK PIK3CA PIK3CA E2F3 E2F3 LOC108298696 LOC108298696 AKT2 AKT2 SHC4 SHC4 ENSCCAP00000018301 ENSCCAP00000018301 GPSM3 GPSM3 DLL4 DLL4 ENSCCAP00000017664 ENSCCAP00000017664 MAPK13 MAPK13 LOC108293303 LOC108293303 PTK2 PTK2 SOS1 SOS1 FOS FOS ADCY9 ADCY9 MAPK1 MAPK1 NOTCH4 NOTCH4 SHC3 SHC3 CDKN1A CDKN1A ENSCCAP00000013944 ENSCCAP00000013944 LOC108282680 LOC108282680 PIK3R3 PIK3R3 ENSCCAP00000012723 ENSCCAP00000012723 ADCY6 ADCY6 ENSCCAP00000012370 ENSCCAP00000012370 EGFR EGFR SOS2 SOS2 BAX BAX ADCY7 ADCY7 RAF1 RAF1 AKT3 AKT3 ENSCCAP00000010305 ENSCCAP00000010305 DLL1 DLL1 SRC SRC PRKACB PRKACB ADCY3 ADCY3 MMP2 MMP2 ABCB11 ABCB11 PIK3CD PIK3CD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK10Mitogen-activated protein kinase. (538 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
LOC108290468Uncharacterized protein; Belongs to the cytochrome P450 family. (497 aa)
E2F2E2F transcription factor 2. (435 aa)
GNASGNAS complex locus. (1044 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1274 aa)
CARM1Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (609 aa)
BCL2BCL2 apoptosis regulator. (240 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
PPP1R14BProtein phosphatase 1 regulatory inhibitor subunit 14B. (147 aa)
LOC108297870Uncharacterized protein. (250 aa)
MAP2K2Mitogen-activated protein kinase kinase 2. (303 aa)
NCOA3Nuclear receptor coactivator. (1417 aa)
RB1RB transcriptional corepressor 1. (927 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ENSCCAP00000003376Protein kinase domain-containing protein. (184 aa)
DLL3Delta like canonical Notch ligand 3. (618 aa)
BADBCL2 associated agonist of cell death. (167 aa)
MDM2Uncharacterized protein. (499 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
LOC108298339Uncharacterized protein. (164 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1517 aa)
LOC108300898Protein kinase domain-containing protein. (271 aa)
SP1Sp1 transcription factor. (786 aa)
MAPK9Mitogen-activated protein kinase. (392 aa)
MAPK11Mitogen-activated protein kinase. (368 aa)
LOC108313247Protein kinase domain-containing protein. (276 aa)
NOTCH3Notch receptor 3. (2321 aa)
ENSCCAP00000038982Uncharacterized protein. (128 aa)
MMP9Matrix metallopeptidase 9. (703 aa)
CSDE1Uncharacterized protein. (844 aa)
LOC108309036Uncharacterized protein. (342 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
IGF1Insulin like growth factor 1. (199 aa)
PIK3R2Uncharacterized protein. (727 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (205 aa)
CCDC170Coiled-coil domain containing 170. (715 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
CEP152Centrosomal protein 152. (1658 aa)
ENSCCAP00000034806Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (260 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
ENSCCAP00000034704SWIB domain-containing protein. (368 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa)
SHC1SHC adaptor protein 1. (577 aa)
NOTCH1Notch receptor 1. (2550 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
LOC108290469Uncharacterized protein; Belongs to the cytochrome P450 family. (472 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (159 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ENSCCAP00000031460Protein kinase domain-containing protein. (272 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
ENSCCAP00000031241Uncharacterized protein. (387 aa)
NCOR1SANT domain-containing protein. (2281 aa)
ENSCCAP00000030012Protein kinase domain-containing protein. (266 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (395 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1262 aa)
CDK4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
E2F1E2F transcription factor 1. (438 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (766 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
SHC2Uncharacterized protein. (536 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
ENSCCAP00000026158CSD_1 domain-containing protein. (440 aa)
NRASUncharacterized protein. (189 aa)
IGF1RTyrosine-protein kinase receptor. (1285 aa)
LOC108285920Uncharacterized protein. (248 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1249 aa)
ESR2Estrogen receptor 2. (530 aa)
ENSCCAP00000022660Uncharacterized protein. (404 aa)
LOC108304334Protein kinase domain-containing protein. (342 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (486 aa)
MTORSerine/threonine-protein kinase mTOR. (2508 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (902 aa)
BIKBCL2 interacting killer. (156 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
E2F3E2F transcription factor 3. (461 aa)
LOC108298696Uncharacterized protein. (349 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
SHC4SHC adaptor protein 4. (628 aa)
ENSCCAP00000018301Uncharacterized protein. (279 aa)
GPSM3G protein signaling modulator 3. (160 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
ENSCCAP00000017664Uncharacterized protein. (235 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
LOC108293303Uncharacterized protein. (593 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1329 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1354 aa)
MAPK1Mitogen-activated protein kinase. (366 aa)
NOTCH4Notch receptor 4. (1993 aa)
SHC3SHC adaptor protein 3. (598 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (158 aa)
ENSCCAP00000013944Uncharacterized protein. (340 aa)
LOC108282680Protein kinase domain-containing protein. (245 aa)
PIK3R3Uncharacterized protein. (577 aa)
ENSCCAP00000012723Uncharacterized protein. (2489 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
ENSCCAP00000012370ANK_REP_REGION domain-containing protein. (518 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
BAXBCL2 associated X, apoptosis regulator. (159 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
AKT3AKT serine/threonine kinase 3. (472 aa)
ENSCCAP00000010305Uncharacterized protein. (181 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
SRCTyrosine-protein kinase. (542 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
ABCB11ATP binding cassette subfamily B member 11. (1321 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1056 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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