36 items (Cebus capucinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABCC5	ATP binding cassette subfamily C member 5. (1437 aa)
	ENSCCAP00000015218	Folate_rec domain-containing protein. (228 aa)
	ENSCCAP00000016714	DHFR domain-containing protein. (171 aa)
	GGH	Folate gamma-glutamyl hydrolase. (318 aa)
	SLC19A1	Solute carrier family 19 member 1. (585 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
	MTHFR	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (656 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
	LOC108292926	MGS domain-containing protein. (536 aa)
	ABCG2	ABC transporter domain-containing protein. (654 aa)
	IKBKG	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (486 aa)
	ABCC3	ATP binding cassette subfamily C member 3. (1516 aa)
	ABCC1	ATP binding cassette subfamily C member 1. (1537 aa)
	FOLR2	Folate receptor beta. (254 aa)
	FOLR2-2	Folate receptor alpha. (255 aa)
	SHMT1	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (483 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
	ENSCCAP00000030445	Folate_rec domain-containing protein. (104 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (761 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (968 aa)
	TYMS	Thymidylat_synt domain-containing protein. (313 aa)
	FPGS	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (568 aa)
	ABCC2	ATP binding cassette subfamily C member 2. (1545 aa)
	ENSCCAP00000013607	SHMT domain-containing protein. (112 aa)
	IL6	Interleukin 6. (212 aa)
	DHFR	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
	ABCC4	ATP binding cassette subfamily C member 4. (1325 aa)
	ALOX12	Arachidonate 12-lipoxygenase, 12S type. (663 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
	ATIC	MGS domain-containing protein. (557 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (551 aa)
	IZUMO1R	IZUMO1 receptor, JUNO. (250 aa)
	LOC108314003	DHFR domain-containing protein. (175 aa)
	LOC108294705	Thymidylat_synt domain-containing protein. (302 aa)
	LOC108306195	MGS domain-containing protein. (593 aa)
	SLC46A1	Solute carrier family 46 member 1. (466 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC1	ABCG2	ENSCCAP00000027920	ENSCCAP00000024233	ATP binding cassette subfamily C member 1.	ABC transporter domain-containing protein.	0.765
ABCC2	ABCG2	ENSCCAP00000040349	ENSCCAP00000024233	ATP binding cassette subfamily C member 2.	ABC transporter domain-containing protein.	0.860
ABCC3	ABCG2	ENSCCAP00000025561	ENSCCAP00000024233	ATP binding cassette subfamily C member 3.	ABC transporter domain-containing protein.	0.528
ABCC4	ABCG2	ENSCCAP00000010636	ENSCCAP00000024233	ATP binding cassette subfamily C member 4.	ABC transporter domain-containing protein.	0.446
ABCC5	ABCG2	ENSCCAP00000014698	ENSCCAP00000024233	ATP binding cassette subfamily C member 5.	ABC transporter domain-containing protein.	0.439
ABCG2	ABCC1	ENSCCAP00000024233	ENSCCAP00000027920	ABC transporter domain-containing protein.	ATP binding cassette subfamily C member 1.	0.765
ABCG2	ABCC2	ENSCCAP00000024233	ENSCCAP00000040349	ABC transporter domain-containing protein.	ATP binding cassette subfamily C member 2.	0.860
ABCG2	ABCC3	ENSCCAP00000024233	ENSCCAP00000025561	ABC transporter domain-containing protein.	ATP binding cassette subfamily C member 3.	0.528
ABCG2	ABCC4	ENSCCAP00000024233	ENSCCAP00000010636	ABC transporter domain-containing protein.	ATP binding cassette subfamily C member 4.	0.446
ABCG2	ABCC5	ENSCCAP00000024233	ENSCCAP00000014698	ABC transporter domain-containing protein.	ATP binding cassette subfamily C member 5.	0.439
ATIC	DHFR	ENSCCAP00000009779	ENSCCAP00000011508	MGS domain-containing protein.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.829
ATIC	ENSCCAP00000013607	ENSCCAP00000009779	ENSCCAP00000013607	MGS domain-containing protein.	SHMT domain-containing protein.	0.948
ATIC	ENSCCAP00000016714	ENSCCAP00000009779	ENSCCAP00000016714	MGS domain-containing protein.	DHFR domain-containing protein.	0.444
ATIC	FPGS	ENSCCAP00000009779	ENSCCAP00000040100	MGS domain-containing protein.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.458
ATIC	LOC108294705	ENSCCAP00000009779	ENSCCAP00000003486	MGS domain-containing protein.	Thymidylat_synt domain-containing protein.	0.543
ATIC	LOC108314003	ENSCCAP00000009779	ENSCCAP00000004116	MGS domain-containing protein.	DHFR domain-containing protein.	0.829
ATIC	MTHFR	ENSCCAP00000009779	ENSCCAP00000021861	MGS domain-containing protein.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.680
ATIC	SHMT1	ENSCCAP00000009779	ENSCCAP00000029191	MGS domain-containing protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.948
ATIC	SHMT2	ENSCCAP00000009779	ENSCCAP00000029579	MGS domain-containing protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.963
ATIC	TYMS	ENSCCAP00000009779	ENSCCAP00000035645	MGS domain-containing protein.	Thymidylat_synt domain-containing protein.	0.543