STRINGSTRING
MAPK9 MAPK9 MSANTD3-TMEFF1 MSANTD3-TMEFF1 GEM GEM BAD BAD JUND JUND ENSCCAP00000003376 ENSCCAP00000003376 PAK3 PAK3 MAP2K2 MAP2K2 PPP1R14B PPP1R14B RPS6KB1 RPS6KB1 ENSCCAP00000005270 ENSCCAP00000005270 PLCG2 PLCG2 PIK3R1 PIK3R1 MAPK10 MAPK10 NCK2 NCK2 PIK3CD PIK3CD SRC SRC NRG2 NRG2 PAK6 PAK6 ELK1 ELK1 PAK2 PAK2 ENSCCAP00000010305 ENSCCAP00000010305 AKT3 AKT3 RAF1 RAF1 LOC108313439 LOC108313439 PLCG1 PLCG1 PRKCA PRKCA NRG4 NRG4 ENSCCAP00000011942 ENSCCAP00000011942 SOS2 SOS2 EGFR EGFR PRKCG PRKCG PIK3R3 PIK3R3 LOC108282680 LOC108282680 ABL1 ABL1 NRG3 NRG3 STAT5A STAT5A CDKN1A CDKN1A SHC3 SHC3 GSK3B GSK3B MAPK1 MAPK1 ABL2 ABL2 EPGN EPGN SOS1 SOS1 PTK2 PTK2 MAP2K7 MAP2K7 SHC4 SHC4 ELK3 ELK3 NCK1 NCK1 AKT2 AKT2 PAK1 PAK1 GAB1 GAB1 PIK3CA PIK3CA MTOR MTOR RPS6KB2 RPS6KB2 PIK3CB PIK3CB CAMK2A CAMK2A CAMK2B CAMK2B CAMK2G CAMK2G CBL CBL REM1 REM1 NRAS NRAS ENSCCAP00000026158 ENSCCAP00000026158 SHC2 SHC2 BRAF BRAF HRAS HRAS LOC108300898 LOC108300898 CBLB CBLB ALKBH4 ALKBH4 GRB2 GRB2 KRAS KRAS MAP2K4 MAP2K4 CRK CRK CAMK2D CAMK2D TGFA TGFA ERBB2 ERBB2 ENSCCAP00000029765 ENSCCAP00000029765 MYC MYC ENSCCAP00000031241 ENSCCAP00000031241 HBEGF HBEGF ENSCCAP00000032379 ENSCCAP00000032379 ERBB3 ERBB3 PAK4 PAK4 REM2 REM2 SHC1 SHC1 AKT1 AKT1 MAPK8 MAPK8 NRG1 NRG1 PAK5 PAK5 STAT5B STAT5B CEP152 CEP152 RRAD RRAD CRKL CRKL ARAF ARAF ARSI ARSI EIF4EBP1 EIF4EBP1 CDKN1B CDKN1B PRKCB PRKCB PIK3R2 PIK3R2 ERBB4 ERBB4 MAPK3 MAPK3 EREG EREG CSDE1 CSDE1 EGF EGF AREG AREG BTC BTC TMEFF2 TMEFF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK9Mitogen-activated protein kinase. (392 aa)
MSANTD3-TMEFF1MSANTD3-TMEFF1 readthrough. (454 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
BADBCL2 associated agonist of cell death. (167 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (350 aa)
ENSCCAP00000003376Protein kinase domain-containing protein. (184 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
MAP2K2Mitogen-activated protein kinase kinase 2. (303 aa)
PPP1R14BProtein phosphatase 1 regulatory inhibitor subunit 14B. (147 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
ENSCCAP00000005270Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (389 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
MAPK10Mitogen-activated protein kinase. (538 aa)
NCK2Cytoplasmic protein. (380 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1056 aa)
SRCTyrosine-protein kinase. (542 aa)
NRG2Neuregulin 2. (846 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
ELK1ETS transcription factor ELK1. (428 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
ENSCCAP00000010305Uncharacterized protein. (181 aa)
AKT3AKT serine/threonine kinase 3. (472 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
LOC108313439Protein kinase domain-containing protein. (247 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
NRG4Neuregulin 4. (115 aa)
ENSCCAP00000011942Protein kinase domain-containing protein. (258 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
PIK3R3Uncharacterized protein. (577 aa)
LOC108282680Protein kinase domain-containing protein. (245 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
NRG3Neuregulin 3. (719 aa)
STAT5ASignal transducer and activator of transcription. (796 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (158 aa)
SHC3SHC adaptor protein 3. (598 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (434 aa)
MAPK1Mitogen-activated protein kinase. (366 aa)
ABL2Tyrosine-protein kinase. (1182 aa)
EPGNEpithelial mitogen. (154 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1329 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (435 aa)
SHC4SHC adaptor protein 4. (628 aa)
ELK3ETS transcription factor ELK3. (407 aa)
NCK1NCK adaptor protein 1. (358 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PAK1Non-specific serine/threonine protein kinase. (549 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MTORSerine/threonine-protein kinase mTOR. (2508 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (486 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha. (446 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma; Belongs to the protein kinase superfamily. (438 aa)
CBLCbl proto-oncogene. (909 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
NRASUncharacterized protein. (189 aa)
ENSCCAP00000026158CSD_1 domain-containing protein. (440 aa)
SHC2Uncharacterized protein. (536 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (766 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
LOC108300898Protein kinase domain-containing protein. (271 aa)
CBLBCbl proto-oncogene B. (981 aa)
ALKBH4AlkB homolog 4, lysine demethylase. (309 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
MAP2K4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (410 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
TGFATransforming growth factor alpha. (165 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
ENSCCAP00000029765SH3 domain-containing protein. (170 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
ENSCCAP00000031241Uncharacterized protein. (387 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
ENSCCAP00000032379Myb_DNA-bind_5 domain-containing protein. (233 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1352 aa)
PAK4Non-specific serine/threonine protein kinase. (593 aa)
REM2GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (340 aa)
SHC1SHC adaptor protein 1. (577 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
NRG1Neuregulin 1. (713 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
STAT5BSignal transducer and activator of transcription. (788 aa)
CEP152Centrosomal protein 152. (1658 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
ARSIArylsulfatase family member I. (569 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (205 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
PIK3R2Uncharacterized protein. (727 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
EREGEpiregulin. (169 aa)
CSDE1Uncharacterized protein. (844 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
AREGAmphiregulin. (275 aa)
BTCBetacellulin. (178 aa)
TMEFF2Transmembrane protein with EGF like and two follistatin like domains 2. (374 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.