STRINGSTRING
CYBB CYBB LOC108305573 LOC108305573 RELA RELA EGLN1 EGLN1 PIK3CD PIK3CD ENSCCAP00000006801 ENSCCAP00000006801 PIK3R1 PIK3R1 LOC108305460 LOC108305460 PLCG2 PLCG2 PDHA1 PDHA1 PFKFB3 PFKFB3 TLR4 TLR4 BCL2 BCL2 RPS6KB1 RPS6KB1 LOC108301760 LOC108301760 EDN1 EDN1 ENSCCAP00000005168 ENSCCAP00000005168 MAP2K2 MAP2K2 EIF4E2 EIF4E2 LOC108306394 LOC108306394 ENSCCAP00000004889 ENSCCAP00000004889 LOC108282470 LOC108282470 ENSCCAP00000003376 ENSCCAP00000003376 ENSCCAP00000003201 ENSCCAP00000003201 ZAN ZAN NPPA NPPA ENSCCAP00000002185 ENSCCAP00000002185 LOC108294221 LOC108294221 VHLL VHLL LOC108304333 LOC108304333 ELOB ELOB EIF4E1B EIF4E1B LOC108293510 LOC108293510 LOC108296889 LOC108296889 TF TF ENSCCAP00000000829 ENSCCAP00000000829 PGK2 PGK2 LOC108308302 LOC108308302 ENSCCAP00000000279 ENSCCAP00000000279 LOC108300898 LOC108300898 ENSCCAP00000000187 ENSCCAP00000000187 ENSCCAP00000000105 ENSCCAP00000000105 MKNK2 MKNK2 CDKN1A CDKN1A MAPK1 MAPK1 ENSCCAP00000014653 ENSCCAP00000014653 ANGPT2 ANGPT2 ENSCCAP00000015574 ENSCCAP00000015574 LOC108291371 LOC108291371 ENO3 ENO3 LOC108311280 LOC108311280 CREBBP CREBBP LOC108295335 LOC108295335 PFKM PFKM STAT3 STAT3 HKDC1 HKDC1 ENSCCAP00000019119 ENSCCAP00000019119 IFNG IFNG HK3 HK3 AKT2 AKT2 SERPINE1 SERPINE1 PIK3CA PIK3CA MTOR MTOR RPS6KB2 RPS6KB2 PFKP PFKP IFNGR1 IFNGR1 ENSCCAP00000021402 ENSCCAP00000021402 ENSCCAP00000021627 ENSCCAP00000021627 ENO2 ENO2 HIF1A HIF1A LOC108282764 LOC108282764 PIK3CB PIK3CB LOC108294561 LOC108294561 EIF4E EIF4E LDHA LDHA INS INS ARNT ARNT ENSCCAP00000023364 ENSCCAP00000023364 IFNGR2 IFNGR2 ENSCCAP00000023514 ENSCCAP00000023514 CAMK2A CAMK2A CAMK2B CAMK2B ENSCCAP00000024727 ENSCCAP00000024727 CAMK2G CAMK2G ALDOC ALDOC TFRC TFRC IGF1R IGF1R ENSCCAP00000025664 ENSCCAP00000025664 ENSCCAP00000025671 ENSCCAP00000025671 LOC108306365 LOC108306365 LDHAL6A LDHAL6A RPS6 RPS6 LDHC LDHC HK2 HK2 LOC108299250 LOC108299250 LOC108293547 LOC108293547 VHL VHL NOS2 NOS2 LOC108284022 LOC108284022 LTF LTF CAMK2D CAMK2D VEGFA VEGFA HK1 HK1 ERBB2 ERBB2 TEK TEK LOC108312582 LOC108312582 TIMP1 TIMP1 EPO EPO ALDOB ALDOB NFKB1 NFKB1 SLC2A1 SLC2A1 PGK1 PGK1 LOC108295199 LOC108295199 LOC108304672 LOC108304672 TBCA TBCA NOS3 NOS3 LOC108296673 LOC108296673 LOC108302977 LOC108302977 ENSCCAP00000034485 ENSCCAP00000034485 AKT1 AKT1 ENSCCAP00000034684 ENSCCAP00000034684 ENSCCAP00000034957 ENSCCAP00000034957 FCGBP FCGBP ENSCCAP00000035313 ENSCCAP00000035313 FLT1 FLT1 ARSI ARSI IL6R IL6R EIF4EBP1 EIF4EBP1 CDKN1B CDKN1B PRKCB PRKCB LDHB LDHB PIK3R2 PIK3R2 EGLN2 EGLN2 IGF1 IGF1 MAPK3 MAPK3 EP300 EP300 GAPDH GAPDH EGF EGF ENSCCAP00000039006 ENSCCAP00000039006 LOC108287731 LOC108287731 RBX1 RBX1 ENSCCAP00000039308 ENSCCAP00000039308 EGLN3 EGLN3 LTBR LTBR ENSCCAP00000039668 ENSCCAP00000039668 ENO1 ENO1 ANGPT4 ANGPT4 ENSCCAP00000013066 ENSCCAP00000013066 MKNK1 MKNK1 LOC108282680 LOC108282680 PIK3R3 PIK3R3 PRKCG PRKCG EGFR EGFR PDHB PDHB IL6 IL6 PDK1 PDK1 ENO4 ENO4 PRKCA PRKCA PLCG1 PLCG1 LOC108290726 LOC108290726 INSR INSR ELOC ELOC LOC108313439 LOC108313439 PFKL PFKL AKT3 AKT3 HMOX1 HMOX1 CUL2 CUL2 ANGPT1 ANGPT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CYBBCytochrome b-245 beta chain. (570 aa)
LOC108305573Glyceraldehyde-3-phosphate dehydrogenase. (325 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
EGLN1Uncharacterized protein. (426 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1056 aa)
ENSCCAP00000006801L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (349 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
LOC108305460Uncharacterized protein. (363 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (409 aa)
PFKFB36-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3. (535 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (832 aa)
BCL2BCL2 apoptosis regulator. (240 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
LOC108301760Uncharacterized protein. (420 aa)
EDN1Endothelin 1. (212 aa)
ENSCCAP00000005168Uncharacterized protein. (98 aa)
MAP2K2Mitogen-activated protein kinase kinase 2. (303 aa)
EIF4E2Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (245 aa)
LOC108306394Glyceraldehyde-3-phosphate dehydrogenase. (316 aa)
ENSCCAP00000004889Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
LOC10828247040S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
ENSCCAP00000003376Protein kinase domain-containing protein. (184 aa)
ENSCCAP00000003201Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
ZANZonadhesin (gene/pseudogene). (2675 aa)
NPPANatriuretic peptide A. (153 aa)
ENSCCAP00000002185Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
LOC10829422140S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (216 aa)
VHLLVHL domain-containing protein. (122 aa)
LOC10830433340S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
ELOBElongin B. (157 aa)
EIF4E1BEukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (238 aa)
LOC108293510Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
LOC108296889L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
TFTransferrin; Belongs to the transferrin family. (700 aa)
ENSCCAP00000000829Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
PGK2Phosphoglycerate kinase. (417 aa)
LOC108308302Uncharacterized protein. (434 aa)
ENSCCAP00000000279Ldh_1_N domain-containing protein. (91 aa)
LOC108300898Protein kinase domain-containing protein. (271 aa)
ENSCCAP00000000187Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
ENSCCAP00000000105Uncharacterized protein. (433 aa)
MKNK2MAPK interacting serine/threonine kinase 2. (509 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (158 aa)
MAPK1Mitogen-activated protein kinase. (366 aa)
ENSCCAP00000014653Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (265 aa)
ANGPT2Angiopoietin 2. (455 aa)
ENSCCAP00000015574L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (346 aa)
LOC108291371Gp_dh_N domain-containing protein. (281 aa)
ENO3Uncharacterized protein. (346 aa)
LOC108311280L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (317 aa)
CREBBPCREB binding protein. (2448 aa)
LOC108295335Enolase_C domain-containing protein. (171 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (851 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
HKDC1Hexokinase domain containing 1. (917 aa)
ENSCCAP00000019119Uncharacterized protein. (129 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
HK3Hexokinase 3. (962 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MTORSerine/threonine-protein kinase mTOR. (2508 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (486 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (784 aa)
IFNGR1Interferon gamma receptor 1. (484 aa)
ENSCCAP00000021402VWFD domain-containing protein. (281 aa)
ENSCCAP00000021627L-lactate dehydrogenase. (217 aa)
ENO2Enolase 2. (434 aa)
HIF1AUncharacterized protein. (848 aa)
LOC108282764Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (308 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC108294561Uncharacterized protein. (718 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (248 aa)
LDHAL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (789 aa)
ENSCCAP00000023364L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (353 aa)
IFNGR2Interferon gamma receptor 2. (336 aa)
ENSCCAP00000023514Uncharacterized protein. (89 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha. (446 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
ENSCCAP00000024727Gp_dh_C domain-containing protein. (177 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma; Belongs to the protein kinase superfamily. (438 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (371 aa)
TFRCTransferrin receptor. (759 aa)
IGF1RTyrosine-protein kinase receptor. (1285 aa)
ENSCCAP00000025664Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (294 aa)
ENSCCAP00000025671Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (118 aa)
LOC108306365Uncharacterized protein. (420 aa)
LDHAL6AL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
RPS640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
LDHCLactate dehydrogenase C; Belongs to the LDH/MDH superfamily. (291 aa)
HK2Hexokinase 2. (917 aa)
LOC108299250Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (263 aa)
LOC108293547Uncharacterized protein. (773 aa)
VHLVon Hippel-Lindau tumor suppressor. (189 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
LOC108284022Uncharacterized protein. (199 aa)
LTFLactotransferrin; Belongs to the transferrin family. (713 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (456 aa)
HK1Uncharacterized protein. (921 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
TEKTEK receptor tyrosine kinase. (1069 aa)
LOC108312582L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (324 aa)
TIMP1TIMP metallopeptidase inhibitor 1. (207 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (194 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (508 aa)
PGK1Phosphoglycerate kinase. (417 aa)
LOC108295199L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (323 aa)
LOC108304672Uncharacterized protein. (424 aa)
TBCATubulin-specific chaperone A; Belongs to the TBCA family. (132 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
LOC108296673Uncharacterized protein. (139 aa)
LOC108302977E1_dh domain-containing protein. (358 aa)
ENSCCAP00000034485Phosphoglycerate kinase. (254 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa)
ENSCCAP00000034684Glyceraldehyde-3-phosphate dehydrogenase. (342 aa)
ENSCCAP00000034957Uncharacterized protein. (843 aa)
FCGBPUncharacterized protein. (1093 aa)
ENSCCAP00000035313L-lactate dehydrogenase. (252 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
ARSIArylsulfatase family member I. (569 aa)
IL6RInterleukin 6 receptor. (468 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (205 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
LDHBL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
PIK3R2Uncharacterized protein. (727 aa)
EGLN2Egl-9 family hypoxia inducible factor 2. (406 aa)
IGF1Insulin like growth factor 1. (199 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
EP300E1A binding protein p300. (2420 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
ENSCCAP00000039006Gp_dh_N domain-containing protein. (264 aa)
LOC108287731Glyceraldehyde-3-phosphate dehydrogenase. (336 aa)
RBX1Ring-box 1. (108 aa)
ENSCCAP00000039308Gp_dh_C domain-containing protein. (112 aa)
EGLN3Egl-9 family hypoxia inducible factor 3. (239 aa)
LTBRLymphotoxin beta receptor. (431 aa)
ENSCCAP00000039668Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (260 aa)
ENO1Uncharacterized protein. (273 aa)
ANGPT4Angiopoietin 4. (503 aa)
ENSCCAP00000013066Uncharacterized protein. (96 aa)
MKNK1Protein kinase domain-containing protein. (458 aa)
LOC108282680Protein kinase domain-containing protein. (245 aa)
PIK3R3Uncharacterized protein. (577 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
IL6Interleukin 6. (212 aa)
PDK1Protein-serine/threonine kinase. (447 aa)
ENO4Enolase 4. (628 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
LOC108290726Phosphoglycerate kinase. (343 aa)
INSRTyrosine-protein kinase receptor. (1352 aa)
ELOCElongin C. (112 aa)
LOC108313439Protein kinase domain-containing protein. (247 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
AKT3AKT serine/threonine kinase 3. (472 aa)
HMOX1Heme oxygenase 1. (297 aa)
CUL2Cullin 2; Belongs to the cullin family. (759 aa)
ANGPT1Angiopoietin 1. (498 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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