STRINGSTRING
GRB2 GRB2 RAC3 RAC3 KRAS KRAS CASP3 CASP3 LOC108282175 LOC108282175 PPP3CA PPP3CA TNFSF10 TNFSF10 VAV1 VAV1 GZMB GZMB ENSCCAP00000031241 ENSCCAP00000031241 NCR1 NCR1 SH3BP2 SH3BP2 KLRC2 KLRC2 PTPN11 PTPN11 LOC108299865 LOC108299865 CSF2 CSF2 ITGAL ITGAL SHC1 SHC1 KLRK1 KLRK1 PTK6 PTK6 PRF1 PRF1 CEP152 CEP152 BID BID ARAF ARAF LOC108293621 LOC108293621 ENSCCAP00000036438 ENSCCAP00000036438 PRKCB PRKCB PIK3R2 PIK3R2 FASLG FASLG MAPK3 MAPK3 CD247 CD247 CSDE1 CSDE1 SH2D1B SH2D1B SRMS SRMS LOC108282174 LOC108282174 HRAS HRAS CD244 CD244 BRAF BRAF SHC2 SHC2 CD48 CD48 ENSCCAP00000026158 ENSCCAP00000026158 NRAS NRAS LCK LCK TYROBP TYROBP HCST HCST LOC108298513 LOC108298513 PPP3R1 PPP3R1 LAT LAT IFNGR2 IFNGR2 ICAM2 ICAM2 ZAP70 ZAP70 PIK3CB PIK3CB ICAM1 ICAM1 VAV2 VAV2 GZMH GZMH IFNGR1 IFNGR1 TNFRSF10A TNFRSF10A FYN FYN PIK3CA PIK3CA PAK1 PAK1 TNF TNF KLRG1 KLRG1 RAC2 RAC2 RAET1E RAET1E IFNG IFNG SHC4 SHC4 NFATC1 NFATC1 ENSCCAP00000018427 ENSCCAP00000018427 PTK2B PTK2B FAS FAS KIR3DL2 KIR3DL2 ENSCCAP00000017128 ENSCCAP00000017128 ENSCCAP00000017017 ENSCCAP00000017017 SOS1 SOS1 LOC108297851 LOC108297851 FCER1G FCER1G IFNAR1 IFNAR1 NFATC2 NFATC2 MAPK1 MAPK1 SHC3 SHC3 SH2D1A SH2D1A LOC108282680 LOC108282680 PIK3R3 PIK3R3 PRKCG PRKCG LOC108298514 LOC108298514 KLRD1 KLRD1 SOS2 SOS2 PRKCA PRKCA PLCG1 PLCG1 RAF1 RAF1 ENSCCAP00000010613 ENSCCAP00000010613 ENSCCAP00000010305 ENSCCAP00000010305 LOC108297856 LOC108297856 VAV3 VAV3 ENSCCAP00000009774 ENSCCAP00000009774 IFNAR2 IFNAR2 ENSCCAP00000009063 ENSCCAP00000009063 LOC108296168 LOC108296168 NCR3 NCR3 PIK3CD PIK3CD PIK3R1 PIK3R1 PLCG2 PLCG2 TNFRSF10B TNFRSF10B PPP3CC PPP3CC MAP2K2 MAP2K2 ENSCCAP00000004537 ENSCCAP00000004537 SYK SYK NCR2 NCR2 ENSCCAP00000003376 ENSCCAP00000003376 RAC1 RAC1 LCP2 LCP2 PPP3CB PPP3CB LOC108297849 LOC108297849 PTPN6 PTPN6 ITGB2 ITGB2 LOC108300898 LOC108300898
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRB2Growth factor receptor bound protein 2. (217 aa)
RAC3Rac family small GTPase 3. (192 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
LOC108282175Uncharacterized protein. (316 aa)
PPP3CASerine/threonine-protein phosphatase. (434 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (281 aa)
VAV1Uncharacterized protein. (899 aa)
GZMBGranzyme B; Belongs to the peptidase S1 family. (247 aa)
ENSCCAP00000031241Uncharacterized protein. (387 aa)
NCR1Natural cytotoxicity triggering receptor 1. (302 aa)
SH3BP2SH3 domain binding protein 2. (621 aa)
KLRC2C-type lectin domain-containing protein. (225 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
LOC108299865Ig-like domain-containing protein. (362 aa)
CSF2Colony stimulating factor 2. (144 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1138 aa)
SHC1SHC adaptor protein 1. (577 aa)
KLRK1Killer cell lectin like receptor K1. (216 aa)
PTK6Tyrosine-protein kinase. (451 aa)
PRF1Perforin 1. (555 aa)
CEP152Centrosomal protein 152. (1658 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (236 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
LOC108293621Uncharacterized protein. (192 aa)
ENSCCAP00000036438Ig-like domain-containing protein. (311 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
PIK3R2Uncharacterized protein. (727 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (281 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
CD247CD247 molecule. (164 aa)
CSDE1Uncharacterized protein. (844 aa)
SH2D1BSH2 domain containing 1B. (132 aa)
SRMSTyrosine-protein kinase. (486 aa)
LOC108282174Ig-like domain-containing protein. (237 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
CD244CD244 molecule. (353 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (766 aa)
SHC2Uncharacterized protein. (536 aa)
CD48CD48 molecule. (227 aa)
ENSCCAP00000026158CSD_1 domain-containing protein. (440 aa)
NRASUncharacterized protein. (189 aa)
LCKTyrosine-protein kinase. (515 aa)
TYROBPTYRO protein tyrosine kinase binding protein. (99 aa)
HCSTHematopoietic cell signal transducer. (91 aa)
LOC108298513Uncharacterized protein. (457 aa)
PPP3R1Uncharacterized protein. (188 aa)
LATLinker for activation of T cells. (250 aa)
IFNGR2Interferon gamma receptor 2. (336 aa)
ICAM2Intercellular adhesion molecule 2. (219 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
ICAM1Intercellular adhesion molecule 1. (537 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
GZMHGranzyme H; Belongs to the peptidase S1 family. (225 aa)
IFNGR1Interferon gamma receptor 1. (484 aa)
TNFRSF10ATNF receptor superfamily member 10a. (419 aa)
FYNTyrosine-protein kinase. (537 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PAK1Non-specific serine/threonine protein kinase. (549 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
KLRG1Killer cell lectin like receptor G1. (192 aa)
RAC2Rac family small GTPase 2. (192 aa)
RAET1EMHC_I-like_Ag-recog domain-containing protein. (213 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
SHC4SHC adaptor protein 4. (628 aa)
NFATC1Nuclear factor of activated T cells 1. (1052 aa)
ENSCCAP00000018427SH2 domain-containing protein. (239 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (990 aa)
FASFas cell surface death receptor. (317 aa)
KIR3DL2Uncharacterized protein. (323 aa)
ENSCCAP00000017128Ig-like domain-containing protein. (200 aa)
ENSCCAP00000017017Ig-like domain-containing protein. (180 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1329 aa)
LOC108297851MHC_I-like_Ag-recog domain-containing protein. (240 aa)
FCER1GFc fragment of IgE receptor Ig. (86 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (519 aa)
NFATC2Nuclear factor of activated T cells 2. (923 aa)
MAPK1Mitogen-activated protein kinase. (366 aa)
SHC3SHC adaptor protein 3. (598 aa)
SH2D1ASH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (125 aa)
LOC108282680Protein kinase domain-containing protein. (245 aa)
PIK3R3Uncharacterized protein. (577 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
LOC108298514Uncharacterized protein. (341 aa)
KLRD1Killer cell lectin like receptor D1. (144 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
ENSCCAP00000010613Ig domain-containing protein. (220 aa)
ENSCCAP00000010305Uncharacterized protein. (181 aa)
LOC108297856MHC_I-like_Ag-recog domain-containing protein. (243 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
ENSCCAP00000009774Uncharacterized protein. (758 aa)
IFNAR2Uncharacterized protein. (516 aa)
ENSCCAP00000009063Uncharacterized protein; Belongs to the peptidase C14A family. (265 aa)
LOC108296168Uncharacterized protein. (167 aa)
NCR3Natural cytotoxicity triggering receptor 3. (191 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1056 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
TNFRSF10BTNF receptor superfamily member 10b. (443 aa)
PPP3CCSerine/threonine-protein phosphatase. (511 aa)
MAP2K2Mitogen-activated protein kinase kinase 2. (303 aa)
ENSCCAP00000004537Uncharacterized protein. (185 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
NCR2Natural cytotoxicity triggering receptor 2. (270 aa)
ENSCCAP00000003376Protein kinase domain-containing protein. (184 aa)
RAC1Rac family small GTPase 1. (171 aa)
LCP2Lymphocyte cytosolic protein 2. (532 aa)
PPP3CBSerine/threonine-protein phosphatase. (533 aa)
LOC108297849MHC_I-like_Ag-recog domain-containing protein. (330 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
ITGB2Integrin beta. (770 aa)
LOC108300898Protein kinase domain-containing protein. (271 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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