STRINGSTRING
IL2 IL2 ITK ITK MAPK3 MAPK3 PIK3R2 PIK3R2 IL5 IL5 BCL10 BCL10 CD28 CD28 PTK6 PTK6 PAK5 PAK5 IL10 IL10 ENSCCAP00000034806 ENSCCAP00000034806 MAPK8 MAPK8 AKT1 AKT1 CD3E CD3E NFATC3 NFATC3 TRBV9 TRBV9 TEC TEC PAK4 PAK4 NFKBIA NFKBIA ENSCCAP00000033156 ENSCCAP00000033156 CSF2 CSF2 PRKCQ PRKCQ ENSCCAP00000031460 ENSCCAP00000031460 ENSCCAP00000031241 ENSCCAP00000031241 NFKB1 NFKB1 CHUK CHUK VAV1 VAV1 ENSCCAP00000030012 ENSCCAP00000030012 ENSCCAP00000029765 ENSCCAP00000029765 PPP3CA PPP3CA CDK4 CDK4 NFKBIB NFKBIB KRAS KRAS GRB2 GRB2 CBLB CBLB MAPK12 MAPK12 CD4 CD4 HRAS HRAS PDCD1 PDCD1 MAPK14 MAPK14 ENSCCAP00000026158 ENSCCAP00000026158 NRAS NRAS CD3G CD3G LCK LCK IKBKG IKBKG CTLA4 CTLA4 RHOA RHOA PTPRC PTPRC MALT1 MALT1 PPP3R1 PPP3R1 LAT LAT ZAP70 ZAP70 LOC108304334 LOC108304334 PIK3CB PIK3CB VAV2 VAV2 FYN FYN PIK3CA PIK3CA PAK1 PAK1 TNF TNF AKT2 AKT2 NCK1 NCK1 IFNG IFNG MAP3K7 MAP3K7 NFATC1 NFATC1 ENSCCAP00000017246 ENSCCAP00000017246 MAP2K7 MAP2K7 MAPK13 MAPK13 SOS1 SOS1 FOS FOS CARD11 CARD11 NFATC2 NFATC2 MAPK1 MAPK1 GSK3B GSK3B LOC108282680 LOC108282680 PIK3R3 PIK3R3 SOS2 SOS2 ENSCCAP00000011942 ENSCCAP00000011942 PLCG1 PLCG1 IL4 IL4 ENSCCAP00000011004 ENSCCAP00000011004 RAF1 RAF1 AKT3 AKT3 ENSCCAP00000010305 ENSCCAP00000010305 IKBKB IKBKB PAK2 PAK2 VAV3 VAV3 ENSCCAP00000009774 ENSCCAP00000009774 PAK6 PAK6 CD40LG CD40LG RELA RELA ENSCCAP00000007627 ENSCCAP00000007627 PIK3CD PIK3CD NFKBIE NFKBIE CD8A CD8A NCK2 NCK2 MAPK10 MAPK10 PIK3R1 PIK3R1 ENSCCAP00000006148 ENSCCAP00000006148 MAP3K14 MAP3K14 PPP3CC PPP3CC ENSCCAP00000005270 ENSCCAP00000005270 DLG1 DLG1 MAP2K2 MAP2K2 RASGRP1 RASGRP1 LOC108317207 LOC108317207 ICOS ICOS PAK3 PAK3 ENSCCAP00000003376 ENSCCAP00000003376 ENSCCAP00000002943 ENSCCAP00000002943 CD3D CD3D LCP2 LCP2 PPP3CB PPP3CB RHOC RHOC GRAP2 GRAP2 LOC108296617 LOC108296617 ENSCCAP00000000984 ENSCCAP00000000984 PTPN6 PTPN6 LOC108300898 LOC108300898 SRMS SRMS TRAC TRAC MAPK9 MAPK9 MAPK11 MAPK11 LOC108313247 LOC108313247 ENSCCAP00000038982 ENSCCAP00000038982 MAP3K8 MAP3K8 PDPK1 PDPK1 CSDE1 CSDE1 CD247 CD247
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
ITKTyrosine-protein kinase. (620 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
PIK3R2Uncharacterized protein. (727 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
BCL10BCL10 immune signaling adaptor. (309 aa)
CD28CD28 molecule. (220 aa)
PTK6Tyrosine-protein kinase. (451 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
IL10Interleukin 10. (178 aa)
ENSCCAP00000034806Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (260 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa)
CD3ECD3e molecule. (198 aa)
NFATC3Nuclear factor of activated T cells 3. (1075 aa)
TRBV9T cell receptor beta variable 9. (134 aa)
TECTyrosine-protein kinase. (631 aa)
PAK4Non-specific serine/threonine protein kinase. (593 aa)
NFKBIANFKB inhibitor alpha. (310 aa)
ENSCCAP00000033156Uncharacterized protein. (130 aa)
CSF2Colony stimulating factor 2. (144 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (710 aa)
ENSCCAP00000031460Protein kinase domain-containing protein. (272 aa)
ENSCCAP00000031241Uncharacterized protein. (387 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (761 aa)
VAV1Uncharacterized protein. (899 aa)
ENSCCAP00000030012Protein kinase domain-containing protein. (266 aa)
ENSCCAP00000029765SH3 domain-containing protein. (170 aa)
PPP3CASerine/threonine-protein phosphatase. (434 aa)
CDK4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
NFKBIBNFKB inhibitor beta. (394 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
CBLBCbl proto-oncogene B. (981 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
CD4CD4 molecule. (457 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PDCD1Programmed cell death 1. (287 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ENSCCAP00000026158CSD_1 domain-containing protein. (440 aa)
NRASUncharacterized protein. (189 aa)
CD3GCD3g molecule. (182 aa)
LCKTyrosine-protein kinase. (515 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (486 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (223 aa)
RHOAUncharacterized protein. (90 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1299 aa)
MALT1MALT1 paracaspase. (823 aa)
PPP3R1Uncharacterized protein. (188 aa)
LATLinker for activation of T cells. (250 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
LOC108304334Protein kinase domain-containing protein. (342 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
FYNTyrosine-protein kinase. (537 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PAK1Non-specific serine/threonine protein kinase. (549 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
NCK1NCK adaptor protein 1. (358 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
NFATC1Nuclear factor of activated T cells 1. (1052 aa)
ENSCCAP00000017246Uncharacterized protein. (59 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (435 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1329 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
CARD11Caspase recruitment domain family member 11. (1156 aa)
NFATC2Nuclear factor of activated T cells 2. (923 aa)
MAPK1Mitogen-activated protein kinase. (366 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (434 aa)
LOC108282680Protein kinase domain-containing protein. (245 aa)
PIK3R3Uncharacterized protein. (577 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
ENSCCAP00000011942Protein kinase domain-containing protein. (258 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (152 aa)
ENSCCAP00000011004Ig-like domain-containing protein. (159 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
AKT3AKT serine/threonine kinase 3. (472 aa)
ENSCCAP00000010305Uncharacterized protein. (181 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
ENSCCAP00000009774Uncharacterized protein. (758 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
ENSCCAP00000007627Ig-like domain-containing protein. (200 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1056 aa)
NFKBIENFKB inhibitor epsilon. (361 aa)
CD8ACD8a molecule. (235 aa)
NCK2Cytoplasmic protein. (380 aa)
MAPK10Mitogen-activated protein kinase. (538 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSCCAP00000006148Ig-like domain-containing protein. (198 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (948 aa)
PPP3CCSerine/threonine-protein phosphatase. (511 aa)
ENSCCAP00000005270Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (389 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
MAP2K2Mitogen-activated protein kinase kinase 2. (303 aa)
RASGRP1RAS guanyl releasing protein 1. (842 aa)
LOC108317207Uncharacterized protein. (161 aa)
ICOSInducible T cell costimulator. (199 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
ENSCCAP00000003376Protein kinase domain-containing protein. (184 aa)
ENSCCAP00000002943Ig-like domain-containing protein. (131 aa)
CD3DCD3d molecule. (171 aa)
LCP2Lymphocyte cytosolic protein 2. (532 aa)
PPP3CBSerine/threonine-protein phosphatase. (533 aa)
RHOCRas homolog family member C. (193 aa)
GRAP2GRB2 related adaptor protein 2. (324 aa)
LOC108296617Uncharacterized protein. (131 aa)
ENSCCAP00000000984Uncharacterized protein. (177 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
LOC108300898Protein kinase domain-containing protein. (271 aa)
SRMSTyrosine-protein kinase. (486 aa)
TRACT cell receptor alpha constant. (177 aa)
MAPK9Mitogen-activated protein kinase. (392 aa)
MAPK11Mitogen-activated protein kinase. (368 aa)
LOC108313247Protein kinase domain-containing protein. (276 aa)
ENSCCAP00000038982Uncharacterized protein. (128 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (379 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (562 aa)
CSDE1Uncharacterized protein. (844 aa)
CD247CD247 molecule. (164 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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