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| | BMT2 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (405 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (392 aa) |
| | RHOQ | Ras homolog family member Q. (205 aa) |
| | PHKA2 | Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1202 aa) |
| | KIAA1671 | KIAA1671. (1797 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (562 aa) |
| | TSC2 | TSC complex subunit 2. (1777 aa) |
| | FOXO1 | Forkhead box O1. (654 aa) |
| | CALM1 | Uncharacterized protein; Belongs to the calmodulin family. (102 aa) |
| | CSDE1 | Uncharacterized protein. (844 aa) |
| | LOC108309036 | Uncharacterized protein. (342 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1305 aa) |
| | PIK3R2 | Uncharacterized protein. (727 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | EIF4EBP1 | Eukaryotic translation initiation factor 4E binding protein 1. (118 aa) |
| | ENSCCAP00000036032 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (382 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (606 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | PVALEF | Parvalbumin like EF-hand containing. (134 aa) |
| | RRAD | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa) |
| | CEP152 | Centrosomal protein 152. (1658 aa) |
| | ENSCCAP00000034957 | Uncharacterized protein. (843 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (276 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (384 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa) |
| | EFCAB3 | EF-hand calcium binding domain 3. (472 aa) |
| | TBCA | Tubulin-specific chaperone A; Belongs to the TBCA family. (132 aa) |
| | SHC1 | SHC adaptor protein 1. (577 aa) |
| | PRKAR2B | Protein kinase cAMP-dependent type II regulatory subunit beta. (418 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa) |
| | PHKG2 | Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily. (406 aa) |
| | FLOT1 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa) |
| | RAPGEF1 | Rap guanine nucleotide exchange factor 1. (1103 aa) |
| | IRS4 | Insulin receptor substrate 4. (1253 aa) |
| | PRKAR2A | Uncharacterized protein. (404 aa) |
| | TMEM145 | Transmembrane protein 145. (563 aa) |
| | ENSCCAP00000031241 | Uncharacterized protein. (387 aa) |
| | CALM3 | Uncharacterized protein; Belongs to the calmodulin family. (161 aa) |
| | CALM2 | Uncharacterized protein; Belongs to the calmodulin family. (188 aa) |
| | G6PC | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (487 aa) |
| | SLC2A4 | Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa) |
| | PPP1R3A | Protein phosphatase 1 regulatory subunit 3A. (1118 aa) |
| | PTPRS | Protein tyrosine phosphatase receptor type S. (1948 aa) |
| | HK1 | Uncharacterized protein. (921 aa) |
| | PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (328 aa) |
| | LOC108284022 | Uncharacterized protein. (199 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (304 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | BUD23 | BUD23 rRNA methyltransferase and ribosome maturation factor. (301 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | ALKBH4 | AlkB homolog 4, lysine demethylase. (309 aa) |
| | CBLB | Cbl proto-oncogene B. (981 aa) |
| | SOCS4 | Suppressor of cytokine signaling 4. (440 aa) |
| | ENSCCAP00000027698 | Uncharacterized protein; Belongs to the calmodulin family. (108 aa) |
| | LIPE | Lipase E, hormone sensitive type. (1072 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | HK2 | Hexokinase 2. (917 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (766 aa) |
| | RPS6 | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa) |
| | SHC2 | Uncharacterized protein. (536 aa) |
| | SORBS1 | Sorbin and SH3 domain containing 1. (1247 aa) |
| | PTPRD | Protein tyrosine phosphatase receptor type D. (1912 aa) |
| | ENSCCAP00000026158 | CSD_1 domain-containing protein. (440 aa) |
| | NRAS | Uncharacterized protein. (189 aa) |
| | RHEB | Ras homolog, mTORC1 binding. (184 aa) |
| | PPP1R3C | Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (317 aa) |
| | ENSCCAP00000025671 | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (118 aa) |
| | REM1 | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa) |
| | CBL | Cbl proto-oncogene. (909 aa) |
| | PHKB | Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1093 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (569 aa) |
| | PPP1R3F | Protein phosphatase 1 regulatory subunit 3F. (795 aa) |
| | PRKAR1B | Protein kinase cAMP-dependent type I regulatory subunit beta. (381 aa) |
| | PTPRF | Protein tyrosine phosphatase receptor type F. (1907 aa) |
| | ENSCCAP00000023653 | Uncharacterized protein. (226 aa) |
| | ENSCCAP00000023514 | Uncharacterized protein. (89 aa) |
| | PHKG1 | Phosphorylase kinase catalytic subunit gamma 1; Belongs to the protein kinase superfamily. (418 aa) |
| | SORBS2 | Sorbin and SH3 domain containing 2. (1198 aa) |
| | ENSCCAP00000023374 | Uncharacterized protein; Belongs to the calmodulin family. (200 aa) |
| | INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa) |
| | GYS2 | Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (709 aa) |
| | EIF4E | Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (248 aa) |
| | FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (483 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (486 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR. (2508 aa) |
| | TSC1 | TSC complex subunit 1. (1149 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | GCK | Phosphotransferase. (466 aa) |
| | PKLR | Pyruvate kinase; Belongs to the pyruvate kinase family. (513 aa) |
| | ENSCCAP00000019950 | Uncharacterized protein. (79 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | PRKAR1A | Protein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (605 aa) |
| | HK3 | Hexokinase 3. (962 aa) |
| | ENSCCAP00000019119 | Uncharacterized protein. (129 aa) |
| | SORBS3 | Sorbin and SH3 domain containing 3. (671 aa) |
| | HKDC1 | Hexokinase domain containing 1. (917 aa) |
| | G6PC3 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa) |
| | ELK3 | ETS transcription factor ELK3. (407 aa) |
| | SHC4 | SHC adaptor protein 4. (628 aa) |
| | PCK2 | Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa) |
| | G6PC2 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa) |
| | GYS1 | Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (737 aa) |
| | EXOC7 | Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (660 aa) |
| | TRIP10 | Thyroid hormone receptor interactor 10. (602 aa) |
| | SOCS2 | Suppressor of cytokine signaling 2. (199 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1329 aa) |
| | PYGL | Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (851 aa) |
| | SREBF2 | Sterol regulatory element binding transcription factor 2. (1145 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (366 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (434 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2458 aa) |
| | SHC3 | SHC adaptor protein 3. (598 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (812 aa) |
| | MKNK2 | MAPK interacting serine/threonine kinase 2. (509 aa) |
| | MYO9B | Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2155 aa) |
| | PYGB | Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (843 aa) |
| | CALML4 | Calmodulin like 4. (196 aa) |
| | ENSCCAP00000013066 | Uncharacterized protein. (96 aa) |
| | MKNK1 | Protein kinase domain-containing protein. (458 aa) |
| | LOC108282680 | Protein kinase domain-containing protein. (245 aa) |
| | INPPL1 | Inositol polyphosphate phosphatase like 1. (1263 aa) |
| | PIK3R3 | Uncharacterized protein. (577 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | INPP5A | Inositol polyphosphate-5-phosphatase A. (374 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1352 aa) |
| | PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa) |
| | CALML6 | Calmodulin like 6. (180 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | AKT3 | AKT serine/threonine kinase 3. (472 aa) |
| | ENSCCAP00000010305 | Uncharacterized protein. (181 aa) |
| | PYGM | Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa) |
| | FASN | Fatty acid synthase. (2541 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | EFCAB13 | EF-hand calcium binding domain 13. (974 aa) |
| | ELK1 | ETS transcription factor ELK1. (428 aa) |
| | ENSCCAP00000009210 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (313 aa) |
| | IRS2 | Insulin receptor substrate 2. (1361 aa) |
| | FBP2 | Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. (339 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | SH2B2 | SH2B adaptor protein 2. (678 aa) |
| | RHEBL1 | RHEB like 1. (164 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1056 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (538 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | PPP1R3E | Protein phosphatase 1 regulatory subunit 3E. (279 aa) |
| | PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa) |
| | ENSCCAP00000005347 | Beta/gamma crystallin 'Greek key' domain-containing protein; Belongs to the beta/gamma-crystallin family. (94 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | PPP1R14B | Protein phosphatase 1 regulatory inhibitor subunit 14B. (147 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2. (303 aa) |
| | ACACA | Acetyl-CoA carboxylase alpha. (2383 aa) |
| | EIF4E2 | Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (245 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (213 aa) |
| | LOC108282470 | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa) |
| | ENSCCAP00000003902 | Uncharacterized protein. (425 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa) |
| | MYO9A | Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2548 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa) |
| | ENSCCAP00000003376 | Protein kinase domain-containing protein. (184 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1185 aa) |
| | LOC108294221 | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (216 aa) |
| | LOC108304333 | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | SOCS3 | Suppressor of cytokine signaling 3. (225 aa) |
| | EIF4E1B | Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (238 aa) |
| | PDE3B | Phosphodiesterase. (1117 aa) |
| | GEM | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa) |
| | PHKA1 | Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1024 aa) |
| | FBP1 | Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa) |
| | CRYBB3 | Crystallin beta B3; Belongs to the beta/gamma-crystallin family. (211 aa) |
| | PPP1R3B | Protein phosphatase 1 regulatory subunit. (285 aa) |
| | LOC108300898 | Protein kinase domain-containing protein. (271 aa) |
