STRINGSTRING
ATF4 ATF4 ATP1A4 ATP1A4 AGTR1 AGTR1 CACNA1C CACNA1C CALM1 CALM1 LOC108309036 LOC108309036 NR4A1 NR4A1 PRKCB PRKCB ATP1A1 ATP1A1 CREB3L1 CREB3L1 ATF2 ATF2 ATP1B1 ATP1B1 ARSI ARSI PVALEF PVALEF PRKD1 PRKD1 ATP1A2 ATP1A2 ATP2B1 ATP2B1 ORAI1 ORAI1 CACNA1G CACNA1G PLCB4 PLCB4 ATP1B3 ATP1B3 ITPR2 ITPR2 PRKACA PRKACA ATP1A3 ATP1A3 ADCY1 ADCY1 PTRHD1 PTRHD1 CALM3 CALM3 CAMK1G CAMK1G CALM2 CALM2 CAMK1 CAMK1 ATP2B2 ATP2B2 CACNA1D CACNA1D ADCY5 ADCY5 CAMK2D CAMK2D PRKD2 PRKD2 KCNK3 KCNK3 ENSCCAP00000027698 ENSCCAP00000027698 LOC108316324 LOC108316324 LIPE LIPE CREB3L4 CREB3L4 POMC POMC LOC108285920 LOC108285920 CAMK2G CAMK2G PRKCE PRKCE ATP1B4 ATP1B4 ADCY8 ADCY8 CAMK2B CAMK2B SCARB1 SCARB1 CAMK2A CAMK2A ITPR3 ITPR3 CAMK4 CAMK4 ENSCCAP00000023374 ENSCCAP00000023374 PLCB2 PLCB2 GNAQ GNAQ CACNA1S CACNA1S NR4A2 NR4A2 ITPR1 ITPR1 CREB5 CREB5 LOC108301104 LOC108301104 ADCY2 ADCY2 CACNA1I CACNA1I LOC108298696 LOC108298696 ATP2B3 ATP2B3 ATP2B4 ATP2B4 ENSCCAP00000018301 ENSCCAP00000018301 DAGLA DAGLA PRKD3 PRKD3 ATP1B2 ATP1B2 ATF1 ATF1 LOC108297130 LOC108297130 CREB3L2 CREB3L2 DAGLB DAGLB ADCY9 ADCY9 CREB3 CREB3 KCNK9 KCNK9 ENSCCAP00000013944 ENSCCAP00000013944 CREB1 CREB1 CAMK1D CAMK1D CALML4 CALML4 CYP21A2 CYP21A2 PRKCG PRKCG ADCY6 ADCY6 CACNA1H CACNA1H LOC108315475 LOC108315475 PRKCA PRKCA ADCY7 ADCY7 CYP11A1 CYP11A1 CALML6 CALML6 ATF6B ATF6B LOC108313439 LOC108313439 GNA11 GNA11 NPR1 NPR1 LDLR LDLR CACNA1F CACNA1F PRKACB PRKACB ADCY3 ADCY3 KCNJ5 KCNJ5 PLCB1 PLCB1 PDE2A PDE2A GNAS GNAS ADCY4 ADCY4 STAR STAR PLCB3 PLCB3 NPPA NPPA CREB3L3 CREB3L3 AGT AGT LOC108298339 LOC108298339
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATF4Activating transcription factor 4. (351 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1030 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (388 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2173 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (102 aa)
LOC108309036Uncharacterized protein. (342 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (652 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
ARSIArylsulfatase family member I. (569 aa)
PVALEFParvalbumin like EF-hand containing. (134 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (884 aa)
ATP1A2ATPase Na+/K+ transporting subunit alpha 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (631 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1226 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (300 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2380 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
ATP1A3Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1112 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
CALM3Uncharacterized protein; Belongs to the calmodulin family. (161 aa)
CAMK1GCalcium/calmodulin dependent protein kinase IG; Belongs to the protein kinase superfamily. (476 aa)
CALM2Uncharacterized protein; Belongs to the calmodulin family. (188 aa)
CAMK1Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (370 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1262 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (860 aa)
KCNK3Potassium channel subfamily K member. (395 aa)
ENSCCAP00000027698Uncharacterized protein; Belongs to the calmodulin family. (108 aa)
LOC108316324Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (263 aa)
LIPELipase E, hormone sensitive type. (1072 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (394 aa)
POMCProopiomelanocortin. (265 aa)
LOC108285920Uncharacterized protein. (248 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma; Belongs to the protein kinase superfamily. (438 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1249 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (563 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha. (446 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2687 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa)
ENSCCAP00000023374Uncharacterized protein; Belongs to the calmodulin family. (200 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
GNAQG protein subunit alpha q. (359 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1877 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2720 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
LOC1083011043Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (372 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (902 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2192 aa)
LOC108298696Uncharacterized protein. (349 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1224 aa)
ENSCCAP00000018301Uncharacterized protein. (279 aa)
DAGLADiacylglycerol lipase alpha. (1042 aa)
PRKD3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (890 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
ATF1Activating transcription factor 1. (270 aa)
LOC1082971303Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (373 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
DAGLBDiacylglycerol lipase beta. (667 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1354 aa)
CREB3cAMP responsive element binding protein 3. (374 aa)
KCNK9Potassium channel subfamily K member. (374 aa)
ENSCCAP00000013944Uncharacterized protein. (340 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
CAMK1DCalcium/calmodulin dependent protein kinase ID; Belongs to the protein kinase superfamily. (385 aa)
CALML4Calmodulin like 4. (196 aa)
CYP21A2Cytochrome P450 family 21 subfamily A member 2; Belongs to the cytochrome P450 family. (491 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2354 aa)
LOC108315475C2 domain-containing protein. (141 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa)
CYP11A1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (521 aa)
CALML6Calmodulin like 6. (180 aa)
ATF6BActivating transcription factor 6 beta. (701 aa)
LOC108313439Protein kinase domain-containing protein. (247 aa)
GNA11G protein subunit alpha 11. (359 aa)
NPR1Guanylate cyclase. (966 aa)
LDLRLow density lipoprotein receptor. (934 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1973 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1215 aa)
PDE2APhosphodiesterase. (944 aa)
GNASGNAS complex locus. (1044 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
STARSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
NPPANatriuretic peptide A. (153 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (415 aa)
AGTAngiotensinogen; Belongs to the serpin family. (486 aa)
LOC108298339Uncharacterized protein. (164 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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