STRINGSTRING
LOC108314454 LOC108314454 ARPC1A ARPC1A VCL VCL CLTCL1 CLTCL1 ACTL7A ACTL7A DNM1 DNM1 PXN PXN CTNNA2 CTNNA2 RHOA RHOA CAV3 CAV3 SEPTIN1 SEPTIN1 CBL CBL ILK ILK RAC1 RAC1 ENSCCAP00000003211 ENSCCAP00000003211 ENSCCAP00000002333 ENSCCAP00000002333 SHC2 SHC2 ENSCCAP00000026738 ENSCCAP00000026738 RHOC RHOC LOC108296617 LOC108296617 RHOG RHOG TMEM250 TMEM250 ENSCCAP00000000984 ENSCCAP00000000984 LOC108293227 LOC108293227 MET MET SEPTIN2 SEPTIN2 SEPTIN14 SEPTIN14 CAV1 CAV1 CRK CRK BCAR1 BCAR1 ENSCCAP00000028575 ENSCCAP00000028575 ARPC5L ARPC5L PIK3R3 PIK3R3 ARHGEF26 ARHGEF26 HCLS1 HCLS1 WASF2 WASF2 ACTL8 ACTL8 ENSCCAP00000033156 ENSCCAP00000033156 CTTN CTTN SHC1 SHC1 DOCK1 DOCK1 CEP152 CEP152 ITGB1 ITGB1 CRKL CRKL PIK3R2 PIK3R2 CLTC CLTC LPXN LPXN MAD2L2 MAD2L2 ENSCCAP00000037500 ENSCCAP00000037500 CLTB CLTB ARPC2 ARPC2 SHC3 SHC3 CTNNB1 CTNNB1 PTK2 PTK2 ENSCCAP00000017246 ENSCCAP00000017246 ELMO3 ELMO3 SHC4 SHC4 ARPC3 ARPC3 CD2AP CD2AP ACTG1 ACTG1 DNM3 DNM3 WASL WASL GAB1 GAB1 ENSCCAP00000020411 ENSCCAP00000020411 PIK3CA PIK3CA SEPTIN10 SEPTIN10 ELMO1 ELMO1 SEPTIN9 SEPTIN9 ACTB ACTB ENSCCAP00000038753 ENSCCAP00000038753 ENSCCAP00000038880 ENSCCAP00000038880 ENSCCAP00000038967 ENSCCAP00000038967 LOC108289094 LOC108289094 SLC25A1 SLC25A1 GOLGA2 GOLGA2 LOC108304702 LOC108304702 PIK3CB PIK3CB ENSCCAP00000012342 ENSCCAP00000012342 LOC108315986 LOC108315986 CAV2 CAV2 WASF1 WASF1 SEPTIN6 SEPTIN6 LOC108299207 LOC108299207 ARPC4 ARPC4 ENSCCAP00000010133 ENSCCAP00000010133 DNM2 DNM2 CTNNA1 CTNNA1 SEPTIN8 SEPTIN8 ARPC5 ARPC5 CLTA CLTA SEPTIN3 SEPTIN3 ENSCCAP00000009436 ENSCCAP00000009436 SEPTIN11 SEPTIN11 SRC SRC LOC108297097 LOC108297097 CTNNA3 CTNNA3 SEPTIN12 SEPTIN12 CDH1 CDH1 ELMO2 ELMO2 ARHGAP10 ARHGAP10 FN1 FN1 PIK3CD PIK3CD ENSCCAP00000007247 ENSCCAP00000007247 ITGA5 ITGA5 PIK3R1 PIK3R1 LOC108317207 LOC108317207 ENSCCAP00000004537 ENSCCAP00000004537
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108314454Uncharacterized protein; Belongs to the actin family. (344 aa)
ARPC1AActin related protein 2/3 complex subunit 1A. (319 aa)
VCLVinculin. (1134 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1640 aa)
ACTL7AActin like 7A; Belongs to the actin family. (434 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (987 aa)
PXNPaxillin. (1085 aa)
CTNNA2Catenin alpha 2. (953 aa)
RHOAUncharacterized protein. (90 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
SEPTIN1Septin 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (392 aa)
CBLCbl proto-oncogene. (909 aa)
ILKIntegrin linked kinase. (483 aa)
RAC1Rac family small GTPase 1. (171 aa)
ENSCCAP00000003211Uncharacterized protein; Belongs to the actin family. (369 aa)
ENSCCAP00000002333Uncharacterized protein. (126 aa)
SHC2Uncharacterized protein. (536 aa)
ENSCCAP00000026738Uncharacterized protein. (164 aa)
RHOCRas homolog family member C. (193 aa)
LOC108296617Uncharacterized protein. (131 aa)
RHOGRas homolog family member G. (191 aa)
TMEM250Transmembrane protein 250. (139 aa)
ENSCCAP00000000984Uncharacterized protein. (177 aa)
LOC108293227Uncharacterized protein. (819 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1404 aa)
SEPTIN2Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (323 aa)
SEPTIN14Septin 14; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (432 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
BCAR1SH3 domain-containing protein. (557 aa)
ENSCCAP00000028575Uncharacterized protein. (124 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
PIK3R3Uncharacterized protein. (577 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (868 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (471 aa)
WASF2WASP family member 2. (498 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
ENSCCAP00000033156Uncharacterized protein. (130 aa)
CTTNCortactin. (600 aa)
SHC1SHC adaptor protein 1. (577 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1885 aa)
CEP152Centrosomal protein 152. (1658 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
PIK3R2Uncharacterized protein. (727 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1673 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (390 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (242 aa)
ENSCCAP00000037500Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (179 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
SHC3SHC adaptor protein 3. (598 aa)
CTNNB1Catenin beta 1. (781 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
ENSCCAP00000017246Uncharacterized protein. (59 aa)
ELMO3Engulfment and cell motility 3. (634 aa)
SHC4SHC adaptor protein 4. (628 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
CD2APCD2 associated protein. (639 aa)
ACTG1Actin gamma 1. (375 aa)
DNM3Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
WASLWASP like actin nucleation promoting factor. (507 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
ENSCCAP00000020411Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (133 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SEPTIN10Septin 10; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (523 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
SEPTIN9Septin 9; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (586 aa)
ACTBActin beta. (375 aa)
ENSCCAP00000038753Uncharacterized protein; Belongs to the actin family. (379 aa)
ENSCCAP00000038880Uncharacterized protein. (126 aa)
ENSCCAP00000038967WD_REPEATS_REGION domain-containing protein. (177 aa)
LOC108289094Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (162 aa)
SLC25A1Solute carrier family 25 member 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (325 aa)
GOLGA2Golgin A2. (1001 aa)
LOC108304702SH3 domain-containing protein. (816 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
ENSCCAP00000012342Uncharacterized protein; Belongs to the actin family. (257 aa)
LOC108315986Uncharacterized protein; Belongs to the actin family. (581 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
WASF1WASP family member 1. (559 aa)
SEPTIN6Septin 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (401 aa)
LOC108299207Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (255 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
ENSCCAP00000010133Uncharacterized protein; Belongs to the actin family. (372 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
CTNNA1Catenin alpha 1. (905 aa)
SEPTIN8Septin 8; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (486 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
SEPTIN3Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (358 aa)
ENSCCAP00000009436Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (150 aa)
SEPTIN11Septin 11; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (432 aa)
SRCTyrosine-protein kinase. (542 aa)
LOC108297097Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (365 aa)
CTNNA3Catenin alpha 3. (895 aa)
SEPTIN12Septin 12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (357 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (814 aa)
ELMO2Engulfment and cell motility 2. (727 aa)
ARHGAP10Rho GTPase activating protein 10. (785 aa)
FN1Fibronectin 1. (2478 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1056 aa)
ENSCCAP00000007247Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (162 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1050 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
LOC108317207Uncharacterized protein. (161 aa)
ENSCCAP00000004537Uncharacterized protein. (185 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
Server load: medium (52%) [HD]