STRINGSTRING
SERPING1 SERPING1 ITGB2 ITGB2 CXCL8 CXCL8 LOC108281394 LOC108281394 TICAM2 TICAM2 TRAF6 TRAF6 RHOC RHOC NLRP3 NLRP3 C4BPA C4BPA IL23A IL23A IRF8 IRF8 LOC108310399 LOC108310399 TLR4 TLR4 MAPK10 MAPK10 ITGA5 ITGA5 C1QB C1QB C1QA C1QA RELA RELA ITGAM ITGAM TMED7 TMED7 CASP7 CASP7 ENSCCAP00000009063 ENSCCAP00000009063 CXCL5 CXCL5 CD14 CD14 EFCAB13 EFCAB13 CALML6 CALML6 LOC108301959 LOC108301959 IRAK1 IRAK1 IL6 IL6 IL12B IL12B CASP1 CASP1 NOD1 NOD1 CALML4 CALML4 C5 C5 MAPK1 MAPK1 CCDC125 CCDC125 CFL1 CFL1 ENSCCAP00000015708 ENSCCAP00000015708 MYD88 MYD88 FOS FOS MAPK13 MAPK13 IRAK4 IRAK4 IRF3 IRF3 C1S C1S ENSCCAP00000018684 ENSCCAP00000018684 TNF TNF C1QC C1QC C4A C4A PYCARD PYCARD C1R C1R C2 C2 ENSCCAP00000023374 ENSCCAP00000023374 IL1B IL1B C3 C3 RHOA RHOA C4BPB C4BPB MAPK14 MAPK14 GNAI3 GNAI3 TICAM1 TICAM1 MAPK12 MAPK12 ENSCCAP00000027698 ENSCCAP00000027698 GNAI1 GNAI1 NOS2 NOS2 C1RL C1RL LY96 LY96 CASP3 CASP3 CXCL6 CXCL6 CALM2 CALM2 NFKB1 NFKB1 CALM3 CALM3 IL12A IL12A EFCAB3 EFCAB3 MAPK8 MAPK8 IL10 IL10 TIRAP TIRAP PVALEF PVALEF ITGB1 ITGB1 TMED3 TMED3 IL1A IL1A MAPK3 MAPK3 ENSCCAP00000037760 ENSCCAP00000037760 CALM1 CALM1 IRF1 IRF1 CFL2 CFL2 MAPK11 MAPK11 MAPK9 MAPK9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SERPING1Serpin family G member 1; Belongs to the serpin family. (531 aa)
ITGB2Integrin beta. (770 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
LOC108281394C-type lectin domain-containing protein. (245 aa)
TICAM2Toll like receptor adaptor molecule 2. (234 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
RHOCRas homolog family member C. (193 aa)
NLRP3NLR family pyrin domain containing 3. (1044 aa)
C4BPAComplement component 4 binding protein alpha. (600 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
IRF8Interferon regulatory factor 8. (426 aa)
LOC108310399ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (187 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (832 aa)
MAPK10Mitogen-activated protein kinase. (538 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1050 aa)
C1QBComplement C1q B chain. (253 aa)
C1QAComplement C1q A chain. (245 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1153 aa)
TMED7Transmembrane p24 trafficking protein 7. (224 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (304 aa)
ENSCCAP00000009063Uncharacterized protein; Belongs to the peptidase C14A family. (265 aa)
CXCL5C-X-C motif chemokine. (115 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa)
EFCAB13EF-hand calcium binding domain 13. (974 aa)
CALML6Calmodulin like 6. (180 aa)
LOC108301959Uncharacterized protein. (569 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (712 aa)
IL6Interleukin 6. (212 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
CASP1Uncharacterized protein; Belongs to the peptidase C14A family. (439 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
CALML4Calmodulin like 4. (196 aa)
C5Complement C5. (1676 aa)
MAPK1Mitogen-activated protein kinase. (366 aa)
CCDC125Coiled-coil domain containing 125. (469 aa)
CFL1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (163 aa)
ENSCCAP00000015708ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (130 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
IRF3Interferon regulatory factor 3. (427 aa)
C1SComplement C1s; Belongs to the peptidase S1 family. (588 aa)
ENSCCAP00000018684Uncharacterized protein. (255 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
C1QCComplement C1q C chain. (243 aa)
C4AUncharacterized protein. (1751 aa)
PYCARDPYD and CARD domain containing. (196 aa)
C1RComplement C1r; Belongs to the peptidase S1 family. (722 aa)
C2Complement C2; Belongs to the peptidase S1 family. (752 aa)
ENSCCAP00000023374Uncharacterized protein; Belongs to the calmodulin family. (200 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
C3Complement C3. (1664 aa)
RHOAUncharacterized protein. (90 aa)
C4BPBComplement component 4 binding protein beta. (259 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
GNAI3G protein subunit alpha i3. (354 aa)
TICAM1Toll like receptor adaptor molecule 1. (522 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
ENSCCAP00000027698Uncharacterized protein; Belongs to the calmodulin family. (108 aa)
GNAI1G protein subunit alpha i1. (354 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
C1RLComplement C1r subcomponent like; Belongs to the peptidase S1 family. (420 aa)
LY96Lymphocyte antigen 96. (160 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
CXCL6C-X-C motif chemokine. (115 aa)
CALM2Uncharacterized protein; Belongs to the calmodulin family. (188 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
CALM3Uncharacterized protein; Belongs to the calmodulin family. (161 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (289 aa)
EFCAB3EF-hand calcium binding domain 3. (472 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
IL10Interleukin 10. (178 aa)
TIRAPTIR domain containing adaptor protein. (244 aa)
PVALEFParvalbumin like EF-hand containing. (134 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
TMED3Transmembrane p24 trafficking protein 3. (217 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (225 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ENSCCAP00000037760Uncharacterized protein. (191 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (102 aa)
IRF1Interferon regulatory factor. (325 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
MAPK11Mitogen-activated protein kinase. (368 aa)
MAPK9Mitogen-activated protein kinase. (392 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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