STRINGSTRING
CALR CALR CXCL8 CXCL8 LOC108298339 LOC108298339 TRAF6 TRAF6 CD3D CD3D PLCB3 PLCB3 ENSCCAP00000002943 ENSCCAP00000002943 FADD FADD PGBD4 PGBD4 CCL2 CCL2 TLR4 TLR4 GNAS GNAS PLCB1 PLCB1 PIK3R1 PIK3R1 MAPK10 MAPK10 C1QB C1QB PIK3CD PIK3CD C1QA C1QA ENSCCAP00000007627 ENSCCAP00000007627 GNAL GNAL RELA RELA PPP2R2B PPP2R2B ACE ACE TGFBR2 TGFBR2 GNA11 GNA11 IKBKB IKBKB GNA14 GNA14 AKT3 AKT3 ENSCCAP00000011004 ENSCCAP00000011004 IRAK1 IRAK1 IL6 IL6 IL12B IL12B PIK3R3 PIK3R3 TGFB3 TGFB3 ENSCCAP00000013944 ENSCCAP00000013944 MAPK1 MAPK1 PPP2R1A PPP2R1A PPP2CA PPP2CA MYD88 MYD88 IL2 IL2 FOS FOS LOC108315287 LOC108315287 MAPK13 MAPK13 IRAK4 IRAK4 PPP2R2A PPP2R2A ENSCCAP00000017896 ENSCCAP00000017896 FAS FAS ENSCCAP00000018301 ENSCCAP00000018301 TGFB2 TGFB2 ENSCCAP00000018684 ENSCCAP00000018684 IFNG IFNG AKT2 AKT2 LOC108298696 LOC108298696 SERPINE1 SERPINE1 TNF TNF PPP2R2D PPP2R2D C1QC C1QC PIK3CA PIK3CA GNAO1 GNAO1 TRAV22 TRAV22 CASP8 CASP8 GNA15 GNA15 IFNGR1 IFNGR1 PIK3CB PIK3CB GNAQ GNAQ PLCB2 PLCB2 IFNGR2 IFNGR2 IL1B IL1B AADAC AADAC C3 C3 IKBKG IKBKG LOC108285920 LOC108285920 CD3G CD3G AADACL2 AADACL2 TGFB1 TGFB1 PPP2R1B PPP2R1B MAPK14 MAPK14 KNG1 KNG1 GNAI3 GNAI3 TICAM1 TICAM1 MAPK12 MAPK12 GNAI1 GNAI1 NOS2 NOS2 MAP2K4 MAP2K4 PPP2R2C PPP2R2C PPP2CB PPP2CB TGFBR1 TGFBR1 CFLAR CFLAR CHUK CHUK NFKB1 NFKB1 ADCY1 ADCY1 CCL5 CCL5 NFKBIA NFKBIA TRBV9 TRBV9 IL12A IL12A PLCB4 PLCB4 CD3E CD3E AKT1 AKT1 MAPK8 MAPK8 IL10 IL10 CCL3L3 CCL3L3 SMAD2 SMAD2 TNFRSF1A TNFRSF1A PIK3R2 PIK3R2 FASLG FASLG MAPK3 MAPK3 CD247 CD247 ENSCCAP00000037760 ENSCCAP00000037760 BDKRB2 BDKRB2 MAPK11 MAPK11 MAPK9 MAPK9 TRAC TRAC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CALRCalreticulin. (424 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
LOC108298339Uncharacterized protein. (164 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
CD3DCD3d molecule. (171 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
ENSCCAP00000002943Ig-like domain-containing protein. (131 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
PGBD4PiggyBac transposable element derived 4. (585 aa)
CCL2C-C motif chemokine. (99 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (832 aa)
GNASGNAS complex locus. (1044 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1215 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
MAPK10Mitogen-activated protein kinase. (538 aa)
C1QBComplement C1q B chain. (253 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1056 aa)
C1QAComplement C1q A chain. (245 aa)
ENSCCAP00000007627Ig-like domain-containing protein. (200 aa)
GNALG protein subunit alpha L. (454 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa)
ACEAngiotensin-converting enzyme. (1308 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
GNA11G protein subunit alpha 11. (359 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
GNA14G protein subunit alpha 14. (355 aa)
AKT3AKT serine/threonine kinase 3. (472 aa)
ENSCCAP00000011004Ig-like domain-containing protein. (159 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (712 aa)
IL6Interleukin 6. (212 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
PIK3R3Uncharacterized protein. (577 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
ENSCCAP00000013944Uncharacterized protein. (340 aa)
MAPK1Mitogen-activated protein kinase. (366 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
LOC108315287TIR domain-containing protein. (1032 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa)
ENSCCAP00000017896SER_THR_PHOSPHATASE domain-containing protein. (233 aa)
FASFas cell surface death receptor. (317 aa)
ENSCCAP00000018301Uncharacterized protein. (279 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
ENSCCAP00000018684Uncharacterized protein. (255 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC108298696Uncharacterized protein. (349 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (475 aa)
C1QCComplement C1q C chain. (243 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
GNAO1G protein subunit alpha o1. (354 aa)
TRAV22T cell receptor alpha variable 22. (137 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (522 aa)
GNA15G protein subunit alpha 15. (374 aa)
IFNGR1Interferon gamma receptor 1. (484 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
GNAQG protein subunit alpha q. (359 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
IFNGR2Interferon gamma receptor 2. (336 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
AADACArylacetamide deacetylase. (399 aa)
C3Complement C3. (1664 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (486 aa)
LOC108285920Uncharacterized protein. (248 aa)
CD3GCD3g molecule. (182 aa)
AADACL2Arylacetamide deacetylase like 2. (401 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (314 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (604 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
KNG1Kininogen 1. (608 aa)
GNAI3G protein subunit alpha i3. (354 aa)
TICAM1Toll like receptor adaptor molecule 1. (522 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
GNAI1G protein subunit alpha i1. (354 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
MAP2K4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (410 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (496 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (761 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
CCL5C-C motif chemokine. (91 aa)
NFKBIANFKB inhibitor alpha. (310 aa)
TRBV9T cell receptor beta variable 9. (134 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (289 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
CD3ECD3e molecule. (198 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
IL10Interleukin 10. (178 aa)
CCL3L3C-C motif chemokine. (93 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
PIK3R2Uncharacterized protein. (727 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (281 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
CD247CD247 molecule. (164 aa)
ENSCCAP00000037760Uncharacterized protein. (191 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (389 aa)
MAPK11Mitogen-activated protein kinase. (368 aa)
MAPK9Mitogen-activated protein kinase. (392 aa)
TRACT cell receptor alpha constant. (177 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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