STRINGSTRING
LOC108300898 LOC108300898 CXCL8 CXCL8 MDM2 MDM2 ENSCCAP00000003376 ENSCCAP00000003376 RB1 RB1 RASSF1 RASSF1 MAP2K2 MAP2K2 E2F2 E2F2 MMP1 MMP1 MMP2 MMP2 CDH1 CDH1 SRC SRC DAPK1 DAPK1 ENSCCAP00000010305 ENSCCAP00000010305 RAF1 RAF1 EGFR EGFR LOC108282680 LOC108282680 CDKN1A CDKN1A MAPK1 MAPK1 ENSCCAP00000017664 ENSCCAP00000017664 DAPK2 DAPK2 E2F3 E2F3 RPS6KA5 RPS6KA5 CCND1 CCND1 LOC108304334 LOC108304334 FGFR3 FGFR3 NRAS NRAS ENSCCAP00000026158 ENSCCAP00000026158 BRAF BRAF HRAS HRAS E2F1 E2F1 KRAS KRAS CDK4 CDK4 VEGFA VEGFA TP53 TP53 ERBB2 ERBB2 MYC MYC TYMP TYMP ENSCCAP00000030012 ENSCCAP00000030012 ENSCCAP00000031241 ENSCCAP00000031241 HBEGF HBEGF ENSCCAP00000031460 ENSCCAP00000031460 CDKN2A CDKN2A THBS1 THBS1 UPK3A UPK3A ENSCCAP00000034704 ENSCCAP00000034704 ENSCCAP00000034806 ENSCCAP00000034806 ARAF ARAF MAPK3 MAPK3 DAPK3 DAPK3 CSDE1 CSDE1 EGF EGF MMP9 MMP9 ENSCCAP00000038982 ENSCCAP00000038982 LOC108313247 LOC108313247
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108300898Protein kinase domain-containing protein. (271 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
MDM2Uncharacterized protein. (499 aa)
ENSCCAP00000003376Protein kinase domain-containing protein. (184 aa)
RB1RB transcriptional corepressor 1. (927 aa)
RASSF1Ras association domain family member 1. (340 aa)
MAP2K2Mitogen-activated protein kinase kinase 2. (303 aa)
E2F2E2F transcription factor 2. (435 aa)
MMP1Matrix metallopeptidase 1. (469 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (814 aa)
SRCTyrosine-protein kinase. (542 aa)
DAPK1Death associated protein kinase 1. (1430 aa)
ENSCCAP00000010305Uncharacterized protein. (181 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
LOC108282680Protein kinase domain-containing protein. (245 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (158 aa)
MAPK1Mitogen-activated protein kinase. (366 aa)
ENSCCAP00000017664Uncharacterized protein. (235 aa)
DAPK2Death associated protein kinase 2; Belongs to the protein kinase superfamily. (488 aa)
E2F3E2F transcription factor 3. (461 aa)
RPS6KA5Ribosomal protein S6 kinase. (800 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
LOC108304334Protein kinase domain-containing protein. (342 aa)
FGFR3Fibroblast growth factor receptor. (808 aa)
NRASUncharacterized protein. (189 aa)
ENSCCAP00000026158CSD_1 domain-containing protein. (440 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (766 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
E2F1E2F transcription factor 1. (438 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
CDK4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (456 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (395 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
TYMPThymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (482 aa)
ENSCCAP00000030012Protein kinase domain-containing protein. (266 aa)
ENSCCAP00000031241Uncharacterized protein. (387 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
ENSCCAP00000031460Protein kinase domain-containing protein. (272 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (159 aa)
THBS1Thrombospondin 1. (1178 aa)
UPK3AUroplakin 3A. (235 aa)
ENSCCAP00000034704SWIB domain-containing protein. (368 aa)
ENSCCAP00000034806Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (260 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
DAPK3Death associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa)
CSDE1Uncharacterized protein. (844 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
MMP9Matrix metallopeptidase 9. (703 aa)
ENSCCAP00000038982Uncharacterized protein. (128 aa)
LOC108313247Protein kinase domain-containing protein. (276 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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