STRINGSTRING
KIT KIT ENSCCAP00000031241 ENSCCAP00000031241 SLC1A5 SLC1A5 SLC2A1 SLC2A1 G6PD G6PD PGAM1 PGAM1 LOC108295199 LOC108295199 LOC108307638 LOC108307638 LOC108302977 LOC108302977 AKT1 AKT1 ENSCCAP00000034957 ENSCCAP00000034957 ENSCCAP00000035313 ENSCCAP00000035313 PARP8 PARP8 TNIK TNIK SLC2A2 SLC2A2 NTRK3 NTRK3 LDHB LDHB PIK3R2 PIK3R2 MAPK3 MAPK3 LOC108313878 LOC108313878 LOC108315180 LOC108315180 CSDE1 CSDE1 LOC108304859 LOC108304859 SCO1 SCO1 LOC108312388 LOC108312388 KRAS KRAS LOC108296889 LOC108296889 RET RET ENSCCAP00000002506 ENSCCAP00000002506 ENSCCAP00000003376 ENSCCAP00000003376 MAP2K2 MAP2K2 PGAM2 PGAM2 PDHA1 PDHA1 NTRK1 NTRK1 PIK3R1 PIK3R1 ENSCCAP00000006801 ENSCCAP00000006801 PTEN PTEN PIK3CD PIK3CD SIRT6 SIRT6 FLT3 FLT3 ENSCCAP00000009793 ENSCCAP00000009793 GLS2 GLS2 TIGAR TIGAR ENSCCAP00000010305 ENSCCAP00000010305 AKT3 AKT3 PFKL PFKL RAF1 RAF1 PDK1 PDK1 SLC7A5 SLC7A5 PDGFRA PDGFRA PDHB PDHB EGFR EGFR PIK3R3 PIK3R3 LOC108282680 LOC108282680 GLS GLS PKM PKM IDH2 IDH2 MAPK1 MAPK1 ENSCCAP00000015574 ENSCCAP00000015574 LOC108311280 LOC108311280 LOC108297965 LOC108297965 ENSCCAP00000016069 ENSCCAP00000016069 FGFR1 FGFR1 PFKM PFKM SLC16A3 SLC16A3 HKDC1 HKDC1 HK3 HK3 AKT2 AKT2 GCK GCK SIRT3 SIRT3 PIK3CA PIK3CA MTOR MTOR PFKP PFKP ENSCCAP00000021627 ENSCCAP00000021627 HIF1A HIF1A PIK3CB PIK3CB LOC108294561 LOC108294561 FGFR2 FGFR2 LDHA LDHA ENSCCAP00000023364 ENSCCAP00000023364 LOC108301202 LOC108301202 FGFR3 FGFR3 ENSCCAP00000024393 ENSCCAP00000024393 NRAS NRAS PARP6 PARP6 ENSCCAP00000026158 ENSCCAP00000026158 LDHAL6A LDHAL6A LDHC LDHC MET MET HK2 HK2 HRAS HRAS PDGFRB PDGFRB LOC108293547 LOC108293547 ENSCCAP00000000279 ENSCCAP00000000279 HK1 HK1 TP53 TP53 ERBB2 ERBB2 MYC MYC LOC108316220 LOC108316220 LOC108312582 LOC108312582 ENSCCAP00000030930 ENSCCAP00000030930 LOC108300898 LOC108300898 IDH1 IDH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
ENSCCAP00000031241Uncharacterized protein. (387 aa)
SLC1A5Amino acid transporter. (543 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (508 aa)
G6PDUncharacterized protein. (560 aa)
PGAM1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (314 aa)
LOC108295199L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (323 aa)
LOC108307638EF-hand_14 domain-containing protein. (542 aa)
LOC108302977E1_dh domain-containing protein. (358 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa)
ENSCCAP00000034957Uncharacterized protein. (843 aa)
ENSCCAP00000035313L-lactate dehydrogenase. (252 aa)
PARP8Poly [ADP-ribose] polymerase. (853 aa)
TNIKTRAF2 and NCK interacting kinase. (1360 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
NTRK3Tyrosine-protein kinase receptor. (864 aa)
LDHBL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
PIK3R2Uncharacterized protein. (727 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
LOC108313878Uncharacterized protein. (523 aa)
LOC108315180Uncharacterized protein. (231 aa)
CSDE1Uncharacterized protein. (844 aa)
LOC108304859Uncharacterized protein. (230 aa)
SCO1SCO cytochrome c oxidase assembly protein 1. (305 aa)
LOC108312388Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (241 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
LOC108296889L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1113 aa)
ENSCCAP00000002506Uncharacterized protein. (239 aa)
ENSCCAP00000003376Protein kinase domain-containing protein. (184 aa)
MAP2K2Mitogen-activated protein kinase kinase 2. (303 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (409 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSCCAP00000006801L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (349 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1056 aa)
SIRT6Sirtuin 6. (382 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (962 aa)
ENSCCAP00000009793Uncharacterized protein. (244 aa)
GLS2ANK_REP_REGION domain-containing protein. (591 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
ENSCCAP00000010305Uncharacterized protein. (181 aa)
AKT3AKT serine/threonine kinase 3. (472 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
PDK1Protein-serine/threonine kinase. (447 aa)
SLC7A5Solute carrier family 7 member 5. (509 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
PIK3R3Uncharacterized protein. (577 aa)
LOC108282680Protein kinase domain-containing protein. (245 aa)
GLSGlutaminase. (625 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (539 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (433 aa)
MAPK1Mitogen-activated protein kinase. (366 aa)
ENSCCAP00000015574L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (346 aa)
LOC108311280L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (317 aa)
LOC108297965Pyruvate kinase; Belongs to the pyruvate kinase family. (471 aa)
ENSCCAP00000016069Uncharacterized protein. (241 aa)
FGFR1Fibroblast growth factor receptor. (827 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (851 aa)
SLC16A3Solute carrier family 16 member 3. (482 aa)
HKDC1Hexokinase domain containing 1. (917 aa)
HK3Hexokinase 3. (962 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
GCKPhosphotransferase. (466 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (398 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MTORSerine/threonine-protein kinase mTOR. (2508 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (784 aa)
ENSCCAP00000021627L-lactate dehydrogenase. (217 aa)
HIF1AUncharacterized protein. (848 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC108294561Uncharacterized protein. (718 aa)
FGFR2Fibroblast growth factor receptor. (782 aa)
LDHAL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
ENSCCAP00000023364L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (353 aa)
LOC108301202Pyruvate kinase; Belongs to the pyruvate kinase family. (512 aa)
FGFR3Fibroblast growth factor receptor. (808 aa)
ENSCCAP00000024393Uncharacterized protein. (69 aa)
NRASUncharacterized protein. (189 aa)
PARP6Poly [ADP-ribose] polymerase. (631 aa)
ENSCCAP00000026158CSD_1 domain-containing protein. (440 aa)
LDHAL6AL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
LDHCLactate dehydrogenase C; Belongs to the LDH/MDH superfamily. (291 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1404 aa)
HK2Hexokinase 2. (917 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1108 aa)
LOC108293547Uncharacterized protein. (773 aa)
ENSCCAP00000000279Ldh_1_N domain-containing protein. (91 aa)
HK1Uncharacterized protein. (921 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (395 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
LOC108316220Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (501 aa)
LOC108312582L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (324 aa)
ENSCCAP00000030930Iso_dh domain-containing protein. (348 aa)
LOC108300898Protein kinase domain-containing protein. (271 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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