STRINGSTRING
RPS6KB1 RPS6KB1 SLC22A1 SLC22A1 PIP5K1B PIP5K1B DGKQ DGKQ PDGFB PDGFB RHEB RHEB NRAS NRAS ENSCCAP00000026158 ENSCCAP00000026158 HRAS HRAS DGKD DGKD PDGFRB PDGFRB LOC108293547 LOC108293547 PLD2 PLD2 GRB2 GRB2 RAC3 RAC3 KRAS KRAS DGKI DGKI CHKB CHKB WASF2 WASF2 ENSCCAP00000031241 ENSCCAP00000031241 PDGFD PDGFD DGKH DGKH DGKA DGKA PDGFC PDGFC JMJD7 JMJD7 SLC22A4 SLC22A4 AKT1 AKT1 MAPK8 MAPK8 SLC22A3 SLC22A3 CHKA CHKA EIF4EBP1 EIF4EBP1 PRKCB PRKCB PIK3R2 PIK3R2 MAPK3 MAPK3 PLPP1 PLPP1 WAS WAS CSDE1 CSDE1 EGF EGF SLC44A2 SLC44A2 TSC2 TSC2 PDPK1 PDPK1 ENSCCAP00000038965 ENSCCAP00000038965 SLC44A1 SLC44A1 MAPK9 MAPK9 SP1 SP1 WASF3 WASF3 PLD1 PLD1 DGKG DGKG PIK3CB PIK3CB HIF1A HIF1A PIP5K1A PIP5K1A RPS6KB2 RPS6KB2 MTOR MTOR TSC1 TSC1 PIK3CA PIK3CA PCYT1A PCYT1A AKT2 AKT2 ENSCCAP00000019674 ENSCCAP00000019674 SLC5A7 SLC5A7 RAC2 RAC2 PDGFA PDGFA DGKZ DGKZ RALGDS RALGDS SOS1 SOS1 FOS FOS GPCPD1 GPCPD1 DGKB DGKB MAPK1 MAPK1 SLC44A4 SLC44A4 SLC44A3 SLC44A3 PLA2G4A PLA2G4A LOC108282680 LOC108282680 PIK3R3 PIK3R3 PRKCG PRKCG EGFR EGFR SOS2 SOS2 PDGFRA PDGFRA LYPLA1 LYPLA1 ENSCCAP00000011758 ENSCCAP00000011758 PRKCA PRKCA PLCG1 PLCG1 SLC44A5 SLC44A5 WASF1 WASF1 ENSCCAP00000011298 ENSCCAP00000011298 RAF1 RAF1 LOC108292046 LOC108292046 AKT3 AKT3 ENSCCAP00000010305 ENSCCAP00000010305 PLA2G4F PLA2G4F PLA2G4B PLA2G4B DGKE DGKE RHEBL1 RHEBL1 CHPT1 CHPT1 PIK3CD PIK3CD MAPK10 MAPK10 PIK3R1 PIK3R1 ENSCCAP00000006612 ENSCCAP00000006612 PCYT1B PCYT1B SLC22A2 SLC22A2 MAP2K2 MAP2K2 ENSCCAP00000004537 ENSCCAP00000004537 PIP5K1C PIP5K1C SLC22A5 SLC22A5 ENSCCAP00000003376 ENSCCAP00000003376 RAC1 RAC1 PLA2G4E PLA2G4E DGKK DGKK PLA2G4D PLA2G4D PLPP3 PLPP3 LOC108300898 LOC108300898
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
SLC22A1Solute carrier family 22 member 1. (552 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (540 aa)
DGKQDiacylglycerol kinase. (938 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
NRASUncharacterized protein. (189 aa)
ENSCCAP00000026158CSD_1 domain-containing protein. (440 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
DGKDDiacylglycerol kinase. (1224 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1108 aa)
LOC108293547Uncharacterized protein. (773 aa)
PLD2Phospholipase. (933 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
RAC3Rac family small GTPase 3. (192 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
DGKIDiacylglycerol kinase. (1055 aa)
CHKBCholine kinase beta. (395 aa)
WASF2WASP family member 2. (498 aa)
ENSCCAP00000031241Uncharacterized protein. (387 aa)
PDGFDPlatelet derived growth factor D; Belongs to the PDGF/VEGF growth factor family. (370 aa)
DGKHDiacylglycerol kinase. (1220 aa)
DGKADiacylglycerol kinase. (708 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
JMJD7Jumonji domain containing 7. (316 aa)
SLC22A4Solute carrier family 22 member 4. (553 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
SLC22A3Solute carrier family 22 member 3. (555 aa)
CHKACholine kinase alpha. (453 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
PIK3R2Uncharacterized protein. (727 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
PLPP1Phospholipid phosphatase 1. (284 aa)
WASWASP actin nucleation promoting factor. (502 aa)
CSDE1Uncharacterized protein. (844 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
SLC44A2Solute carrier family 44 member 2; Belongs to the CTL (choline transporter-like) family. (658 aa)
TSC2TSC complex subunit 2. (1777 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (562 aa)
ENSCCAP00000038965acidPPc domain-containing protein. (275 aa)
SLC44A1Solute carrier family 44 member 1; Belongs to the CTL (choline transporter-like) family. (719 aa)
MAPK9Mitogen-activated protein kinase. (392 aa)
SP1Sp1 transcription factor. (786 aa)
WASF3WASP family member 3. (502 aa)
PLD1Phospholipase. (1074 aa)
DGKGDiacylglycerol kinase. (791 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
HIF1AUncharacterized protein. (848 aa)
PIP5K1APIPK domain-containing protein. (575 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (486 aa)
MTORSerine/threonine-protein kinase mTOR. (2508 aa)
TSC1TSC complex subunit 1. (1149 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PCYT1APhosphate cytidylyltransferase 1, choline, alpha. (380 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ENSCCAP00000019674acidPPc domain-containing protein. (287 aa)
SLC5A7Solute carrier family 5 member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (530 aa)
RAC2Rac family small GTPase 2. (192 aa)
PDGFAPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (211 aa)
DGKZDiacylglycerol kinase. (1120 aa)
RALGDSUncharacterized protein. (910 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1329 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
GPCPD1Glycerophosphocholine phosphodiesterase 1. (658 aa)
DGKBDiacylglycerol kinase. (695 aa)
MAPK1Mitogen-activated protein kinase. (366 aa)
SLC44A4Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family. (709 aa)
SLC44A3Solute carrier family 44 member 3; Belongs to the CTL (choline transporter-like) family. (650 aa)
PLA2G4APhospholipase A2. (741 aa)
LOC108282680Protein kinase domain-containing protein. (245 aa)
PIK3R3Uncharacterized protein. (577 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
LYPLA1Abhydrolase_2 domain-containing protein. (230 aa)
ENSCCAP00000011758PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (191 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
SLC44A5Solute carrier family 44 member 5; Belongs to the CTL (choline transporter-like) family. (719 aa)
WASF1WASP family member 1. (559 aa)
ENSCCAP00000011298acidPPc domain-containing protein. (237 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
LOC108292046Abhydrolase_2 domain-containing protein. (217 aa)
AKT3AKT serine/threonine kinase 3. (472 aa)
ENSCCAP00000010305Uncharacterized protein. (181 aa)
PLA2G4FPhospholipase A2. (849 aa)
PLA2G4BPhospholipase A2. (781 aa)
DGKEDiacylglycerol kinase. (567 aa)
RHEBL1RHEB like 1. (164 aa)
CHPT1Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (406 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1056 aa)
MAPK10Mitogen-activated protein kinase. (538 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSCCAP00000006612Abhydrolase_2 domain-containing protein. (230 aa)
PCYT1BPhosphate cytidylyltransferase 1, choline, beta. (369 aa)
SLC22A2Solute carrier family 22 member 2. (519 aa)
MAP2K2Mitogen-activated protein kinase kinase 2. (303 aa)
ENSCCAP00000004537Uncharacterized protein. (185 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (707 aa)
SLC22A5Solute carrier family 22 member 5. (581 aa)
ENSCCAP00000003376Protein kinase domain-containing protein. (184 aa)
RAC1Rac family small GTPase 1. (171 aa)
PLA2G4EPhospholipase A2. (863 aa)
DGKKDiacylglycerol kinase. (1091 aa)
PLA2G4DPhospholipase A2. (817 aa)
PLPP3acidPPc domain-containing protein. (311 aa)
LOC108300898Protein kinase domain-containing protein. (271 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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