STRINGSTRING
MAP3K7 MAP3K7 ENSCCAP00000018808 ENSCCAP00000018808 PDGFA PDGFA KDR KDR MAP2K6 MAP2K6 IFNG IFNG RAC2 RAC2 PLAT PLAT ACTG1 ACTG1 ENSCCAP00000019711 ENSCCAP00000019711 PRKCZ PRKCZ AKT2 AKT2 ENSCCAP00000019982 ENSCCAP00000019982 TNF TNF DUSP1 DUSP1 KEAP1 KEAP1 PIK3CA PIK3CA ENSCCAP00000020794 ENSCCAP00000020794 LOC108292930 LOC108292930 ACVR2B ACVR2B SDC2 SDC2 ICAM1 ICAM1 ENSCCAP00000021762 ENSCCAP00000021762 PIK3CB PIK3CB PRKAA1 PRKAA1 ENSCCAP00000022137 ENSCCAP00000022137 GSTO2 GSTO2 ENSCCAP00000023374 ENSCCAP00000023374 IL1B IL1B LOC108295971 LOC108295971 ARHGEF2 ARHGEF2 ENSCCAP00000024201 ENSCCAP00000024201 RHOA RHOA NPPC NPPC MAP2K5 MAP2K5 GSTM3 GSTM3 ENSCCAP00000005764 ENSCCAP00000005764 MGST2 MGST2 BCL2 BCL2 VCAM1 VCAM1 EDN1 EDN1 PECAM1 PECAM1 MAP3K5 MAP3K5 ASS1 ASS1 TXN TXN LOC108308711 LOC108308711 LOC108302705 LOC108302705 ENSCCAP00000004537 ENSCCAP00000004537 CCL2 CCL2 MEF2C MEF2C ACTL7A ACTL7A ENSCCAP00000003354 ENSCCAP00000003354 RAC1 RAC1 LOC108298288 LOC108298288 ENSCCAP00000003211 ENSCCAP00000003211 ENSCCAP00000003005 ENSCCAP00000003005 ENSCCAP00000002333 ENSCCAP00000002333 TXNDC8 TXNDC8 RHOC RHOC ENSCCAP00000001652 ENSCCAP00000001652 LOC108314127 LOC108314127 CAV3 CAV3 IKBKG IKBKG LOC108314134 LOC108314134 PTTG1IP PTTG1IP ENSCCAP00000025678 ENSCCAP00000025678 ENSCCAP00000025755 ENSCCAP00000025755 PDGFB PDGFB SUMO2 SUMO2 ENSCCAP00000026738 ENSCCAP00000026738 MAPK14 MAPK14 PIAS4 PIAS4 LOC108290619 LOC108290619 SDC1 SDC1 ENSCCAP00000027518 ENSCCAP00000027518 MAPK12 MAPK12 ENSCCAP00000027698 ENSCCAP00000027698 TXN2 TXN2 CAV1 CAV1 RAC3 RAC3 LOC108283121 LOC108283121 MAP2K4 MAP2K4 PVALEF PVALEF GPC1 GPC1 IL1A IL1A SDC4 SDC4 BMP4 BMP4 TNFRSF1A TNFRSF1A PIK3R2 PIK3R2 MEF2A MEF2A MGST3 MGST3 ITGA2B ITGA2B ENSCCAP00000038024 ENSCCAP00000038024 CALM1 CALM1 ACTB ACTB ENSCCAP00000038753 ENSCCAP00000038753 ENSCCAP00000038808 ENSCCAP00000038808 MMP9 MMP9 LOC108289796 LOC108289796 LOC108281757 LOC108281757 GSTP1 GSTP1 LOC108282244 LOC108282244 MAPK11 MAPK11 IL1R1 IL1R1 MAPK9 MAPK9 VEGFA VEGFA TP53 TP53 NOX1 NOX1 SELE SELE ENSCCAP00000030343 ENSCCAP00000030343 ITGB3 ITGB3 ACTL8 ACTL8 CALM2 CALM2 CHUK CHUK NFKB1 NFKB1 CALM3 CALM3 IL1R2 IL1R2 LOC108284042 LOC108284042 NFE2L2 NFE2L2 GSTM1 GSTM1 NQO1 NQO1 LOC108286539 LOC108286539 SQSTM1 SQSTM1 GSTO1 GSTO1 CDH5 CDH5 HSP90AA1 HSP90AA1 BMPR1A BMPR1A ACVR2A ACVR2A NOS3 NOS3 AKT1 AKT1 MAPK8 MAPK8 PRKAA2 PRKAA2 ENSCCAP00000035128 ENSCCAP00000035128 THBD THBD PIK3R1 PIK3R1 MAPK10 MAPK10 CYBA CYBA NCF2 NCF2 GSTA4 GSTA4 PIK3CD PIK3CD ACVR1 ACVR1 CTSL CTSL MMP2 MMP2 RELA RELA SRC SRC MGST1 MGST1 LOC108282243 LOC108282243 HMOX1 HMOX1 ENSCCAP00000010133 ENSCCAP00000010133 IKBKB IKBKB AKT3 AKT3 CALML6 CALML6 ENSCCAP00000011053 ENSCCAP00000011053 ENSCCAP00000011303 ENSCCAP00000011303 CAV2 CAV2 LOC108314454 LOC108314454 ENSCCAP00000011758 ENSCCAP00000011758 LOC108315986 LOC108315986 ITGAV ITGAV NCF1 NCF1 NOXA1 NOXA1 ENSCCAP00000012342 ENSCCAP00000012342 ENSCCAP00000012432 ENSCCAP00000012432 PIK3R3 PIK3R3 LOC108314132 LOC108314132 CALML4 CALML4 SUMO3 SUMO3 HSP90B1 HSP90B1 ENSCCAP00000013909 ENSCCAP00000013909 BMPR2 BMPR2 ENSCCAP00000015363 ENSCCAP00000015363 CTNNB1 CTNNB1 FOS FOS TRPV4 TRPV4 PTK2 PTK2 KLF2 KLF2 MAPK13 MAPK13 BMPR1B BMPR1B MAP2K7 MAP2K7 ENSCCAP00000035255 ENSCCAP00000035255 TXNDC2 TXNDC2 MAPK7 MAPK7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
ENSCCAP00000018808Uncharacterized protein. (68 aa)
PDGFAPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (211 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
RAC2Rac family small GTPase 2. (192 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (563 aa)
ACTG1Actin gamma 1. (375 aa)
ENSCCAP00000019711Rad60-SLD domain-containing protein. (68 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (605 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ENSCCAP00000019982Rad60-SLD domain-containing protein. (74 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
KEAP1Kelch like ECH associated protein 1. (563 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ENSCCAP00000020794Uncharacterized protein. (99 aa)
LOC108292930Uncharacterized protein. (428 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
ICAM1Intercellular adhesion molecule 1. (537 aa)
ENSCCAP00000021762Uncharacterized protein. (251 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
ENSCCAP00000022137Uncharacterized protein. (65 aa)
GSTO2Glutathione S-transferase omega 2; Belongs to the GST superfamily. (250 aa)
ENSCCAP00000023374Uncharacterized protein; Belongs to the calmodulin family. (200 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
LOC108295971Small ubiquitin-related modifier. (75 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1031 aa)
ENSCCAP00000024201Ubiquitin-like domain-containing protein. (109 aa)
RHOAUncharacterized protein. (90 aa)
NPPCNatriuretic peptide C. (127 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
GSTM3Glutathione S-transferase. (225 aa)
ENSCCAP00000005764GST N-terminal domain-containing protein. (67 aa)
MGST2Microsomal glutathione S-transferase 2. (147 aa)
BCL2BCL2 apoptosis regulator. (240 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
EDN1Endothelin 1. (212 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (738 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1333 aa)
ASS1Uncharacterized protein. (412 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
LOC108308711Uncharacterized protein. (157 aa)
LOC108302705Glutathione S-transferase. (224 aa)
ENSCCAP00000004537Uncharacterized protein. (185 aa)
CCL2C-C motif chemokine. (99 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
ACTL7AActin like 7A; Belongs to the actin family. (434 aa)
ENSCCAP00000003354Uncharacterized protein. (112 aa)
RAC1Rac family small GTPase 1. (171 aa)
LOC108298288Glutathione S-transferase. (208 aa)
ENSCCAP00000003211Uncharacterized protein; Belongs to the actin family. (369 aa)
ENSCCAP00000003005Uncharacterized protein. (118 aa)
ENSCCAP00000002333Uncharacterized protein. (126 aa)
TXNDC8Thioredoxin domain containing 8. (127 aa)
RHOCRas homolog family member C. (193 aa)
ENSCCAP00000001652Thioredoxin domain-containing protein. (91 aa)
LOC108314127Glutathione S-transferase. (193 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (486 aa)
LOC108314134Uncharacterized protein; Belongs to the GST superfamily. (222 aa)
PTTG1IPPTTG1 interacting protein. (180 aa)
ENSCCAP00000025678Uncharacterized protein. (389 aa)
ENSCCAP00000025755Thioredoxin domain-containing protein. (154 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
SUMO2Small ubiquitin-related modifier. (80 aa)
ENSCCAP00000026738Uncharacterized protein. (164 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PIAS4Protein inhibitor of activated STAT 4. (543 aa)
LOC108290619HATPase_c domain-containing protein. (693 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
ENSCCAP00000027518Ubiquitin-like domain-containing protein. (122 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
ENSCCAP00000027698Uncharacterized protein; Belongs to the calmodulin family. (108 aa)
TXN2Thioredoxin 2. (162 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
RAC3Rac family small GTPase 3. (192 aa)
LOC108283121GST C-terminal domain-containing protein. (103 aa)
MAP2K4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (410 aa)
PVALEFParvalbumin like EF-hand containing. (134 aa)
GPC1Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (225 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (199 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
PIK3R2Uncharacterized protein. (727 aa)
MEF2AMyocyte enhancer factor 2A. (502 aa)
MGST3Uncharacterized protein. (166 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1039 aa)
ENSCCAP00000038024Uncharacterized protein. (368 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (102 aa)
ACTBActin beta. (375 aa)
ENSCCAP00000038753Uncharacterized protein; Belongs to the actin family. (379 aa)
ENSCCAP00000038808Glutathione S-transferase. (198 aa)
MMP9Matrix metallopeptidase 9. (703 aa)
LOC108289796Thioredoxin domain-containing protein. (84 aa)
LOC108281757Uncharacterized protein. (203 aa)
GSTP1Uncharacterized protein. (210 aa)
LOC108282244Uncharacterized protein; Belongs to the GST superfamily. (239 aa)
MAPK11Mitogen-activated protein kinase. (368 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
MAPK9Mitogen-activated protein kinase. (392 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (456 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (395 aa)
NOX1NADPH oxidase 1. (564 aa)
SELESelectin E. (610 aa)
ENSCCAP00000030343Rad60-SLD domain-containing protein. (107 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (939 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
CALM2Uncharacterized protein; Belongs to the calmodulin family. (188 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (761 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
CALM3Uncharacterized protein; Belongs to the calmodulin family. (161 aa)
IL1R2Interleukin 1 receptor type 2. (397 aa)
LOC108284042Uncharacterized protein. (453 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
GSTM1Glutathione S-transferase. (179 aa)
NQO1NAD(P)H quinone dehydrogenase 1. (328 aa)
LOC108286539Glutathione S-transferase. (192 aa)
SQSTM1Sequestosome 1. (439 aa)
GSTO1Glutathione S-transferase omega 1. (241 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
HSP90AA1HATPase_c domain-containing protein. (722 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (432 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
ENSCCAP00000035128HATPase_c domain-containing protein. (650 aa)
THBDThrombomodulin. (588 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
MAPK10Mitogen-activated protein kinase. (538 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (193 aa)
NCF2Neutrophil cytosolic factor 2. (526 aa)
GSTA4Glutathione S-transferase alpha 4; Belongs to the GST superfamily. (222 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1056 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
CTSLCathepsin L; Belongs to the peptidase C1 family. (333 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
SRCTyrosine-protein kinase. (542 aa)
MGST1Microsomal glutathione S-transferase 1. (155 aa)
LOC108282243Uncharacterized protein; Belongs to the GST superfamily. (241 aa)
HMOX1Heme oxygenase 1. (297 aa)
ENSCCAP00000010133Uncharacterized protein; Belongs to the actin family. (372 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
AKT3AKT serine/threonine kinase 3. (472 aa)
CALML6Calmodulin like 6. (180 aa)
ENSCCAP00000011053Ubiquitin-like domain-containing protein. (71 aa)
ENSCCAP00000011303Uncharacterized protein. (104 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
LOC108314454Uncharacterized protein; Belongs to the actin family. (344 aa)
ENSCCAP00000011758PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (191 aa)
LOC108315986Uncharacterized protein; Belongs to the actin family. (581 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1047 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
NOXA1NADPH oxidase activator 1. (458 aa)
ENSCCAP00000012342Uncharacterized protein; Belongs to the actin family. (257 aa)
ENSCCAP00000012432Rad60-SLD domain-containing protein. (54 aa)
PIK3R3Uncharacterized protein. (577 aa)
LOC108314132Glutathione S-transferase. (222 aa)
CALML4Calmodulin like 4. (196 aa)
SUMO3Ubiquitin-like domain-containing protein. (133 aa)
HSP90B1HATPase_c domain-containing protein. (804 aa)
ENSCCAP00000013909Uncharacterized protein. (97 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (961 aa)
ENSCCAP00000015363Rad60-SLD domain-containing protein. (94 aa)
CTNNB1Catenin beta 1. (781 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
KLF2Kruppel like factor 2. (354 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (435 aa)
ENSCCAP00000035255Rad60-SLD domain-containing protein. (72 aa)
TXNDC2Thioredoxin domain-containing protein. (323 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (816 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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