STRINGSTRING
GPR18 GPR18 NSL1 NSL1 TAGLN TAGLN NCR3 NCR3 C1RL C1RL CAMK2N2 CAMK2N2 VPS29 VPS29 MRPS15 MRPS15 SPATA2L SPATA2L DDB1 DDB1 CD34 CD34 LCK LCK TCF19 TCF19 MYD88 MYD88 RASGRP1 RASGRP1 TOP1 TOP1 TLR7 TLR7 AASDHPPT AASDHPPT HLA-E HLA-E STAMBPL1 STAMBPL1 LECT2 LECT2 NTRK1 NTRK1 GINS2 GINS2 LOC105582733 LOC105582733 LARP7 LARP7 TNFRSF10D TNFRSF10D BCL2L11 BCL2L11 APAF1 APAF1 IL4 IL4 MR1 MR1 TNIP1 TNIP1 ESF1 ESF1 FAS FAS TLR9 TLR9 FASTK FASTK SF3B2 SF3B2 GOLT1B GOLT1B FBXO8 FBXO8 CSF2 CSF2 MAPK14 MAPK14 PRPF19 PRPF19 CXCL13 CXCL13 HSP90AA1 HSP90AA1 CLEC4C CLEC4C OLFML3 OLFML3 LOC105600181 LOC105600181 IL12A IL12A ZNF75A ZNF75A ITPR1 ITPR1 VMAC VMAC LTF LTF SIPA1 SIPA1 SEPTIN10 SEPTIN10 CCL22 CCL22 MYNN MYNN PLA2G7 PLA2G7 ENSCATP00000036547 ENSCATP00000036547 RUNX1 RUNX1 TSPAN7 TSPAN7 ENSCATP00000035508 ENSCATP00000035508 NOS3 NOS3 HMCES HMCES ENSCATP00000034919 ENSCATP00000034919 KIF26B KIF26B MS4A6E MS4A6E EEF2 EEF2 POU2AF1 POU2AF1 STAMBP STAMBP ARRB1 ARRB1 LOC105600182 LOC105600182 ENSCATP00000033319 ENSCATP00000033319 ACKR1 ACKR1 ABO ABO ANPEP ANPEP AP1S2 AP1S2 CCNA1 CCNA1 CD200R1L CD200R1L ENSCATP00000031459 ENSCATP00000031459 MED30 MED30 CD44 CD44 NRTN NRTN CBX2 CBX2 CD4 CD4 LOC105583051 LOC105583051 HLA-DPB1 HLA-DPB1 ACAD9 ACAD9 LRRC25 LRRC25 DSTYK DSTYK ENSCATP00000029349 ENSCATP00000029349 LAMTOR3 LAMTOR3 NEK9 NEK9 CRLF2 CRLF2 ENSCATP00000028799 ENSCATP00000028799 GSTK1 GSTK1 ENSCATP00000028631 ENSCATP00000028631 TMEM18 TMEM18 NXT2 NXT2 LOC105587027 LOC105587027 IL10 IL10 DERL2 DERL2 BTLA BTLA SIGLEC10 SIGLEC10 SLIRP SLIRP TOR1AIP1 TOR1AIP1 CMC2 CMC2 VAMP2 VAMP2 CCKBR CCKBR ENSCATP00000024947 ENSCATP00000024947 ENSCATP00000024886 ENSCATP00000024886 GPNMB GPNMB VTCN1 VTCN1 ENSCATP00000024269 ENSCATP00000024269 SLC2A2 SLC2A2 RSL24D1 RSL24D1 PROM1 PROM1 LOC105573012 LOC105573012 OSTC OSTC IRAK3 IRAK3 LOC105600307 LOC105600307 NSD3 NSD3 IFNG IFNG LOC105599822 LOC105599822 ELOC ELOC CD8B CD8B IL2 IL2 TIRAP TIRAP IL5RA IL5RA ERLIN1 ERLIN1 TMEM107 TMEM107 PTGS2 PTGS2 ACADVL ACADVL RCAN3 RCAN3 NUSAP1 NUSAP1 RASA3 RASA3 ICMT ICMT CD86 CD86 NUP98 NUP98 MS4A7 MS4A7 CLEC4D CLEC4D LOC105575605 LOC105575605 CYBB CYBB IDO1 IDO1 ENSCATP00000019220 ENSCATP00000019220 SS18L2 SS18L2 PHF23 PHF23 TNFRSF11A TNFRSF11A SMIM8 SMIM8 PDPK1 PDPK1 FAM162A FAM162A ITGAX ITGAX CD80 CD80 UBTD2 UBTD2 DEDD DEDD IL1B IL1B GEM GEM CD83 CD83 TNFSF13B TNFSF13B TSC1 TSC1 ENSCATP00000017574 ENSCATP00000017574 ENSCATP00000017128 ENSCATP00000017128 ADAM19 ADAM19 SDHAF3 SDHAF3 IL31 IL31 MKKS MKKS TMUB1 TMUB1 CCL18 CCL18 CFLAR CFLAR LOC105579876 LOC105579876 IRF7 IRF7 RB1CC1 RB1CC1 CYP21A2 CYP21A2 KTN1 KTN1 LOC105572204 LOC105572204 IL13 IL13 APC APC PDCL3 PDCL3 ENSCATP00000012999 ENSCATP00000012999 DUSP22 DUSP22 MSANTD4 MSANTD4 MS4A4A MS4A4A TAOK3 TAOK3 GAB3 GAB3 METTL5 METTL5 SLC7A5 SLC7A5 HLA-DQB1 HLA-DQB1 SIGLEC9 SIGLEC9 TADA2A TADA2A ENSCATP00000010534 ENSCATP00000010534 NFATC1 NFATC1 DPP4 DPP4 SEMA7A SEMA7A SDHC SDHC NR4A3 NR4A3 RAP1GDS1 RAP1GDS1 LOC105587411 LOC105587411 PECAM1 PECAM1 KDR KDR ENSCATP00000008703 ENSCATP00000008703 ZDHHC4 ZDHHC4 CD40 CD40 GATA1 GATA1 TNFSF11 TNFSF11 PTPRC PTPRC FUNDC2 FUNDC2 ICOSLG ICOSLG LRP8 LRP8 ENSCATP00000007212 ENSCATP00000007212 ENY2-2 ENY2-2 DLST DLST ENSCATP00000006720 ENSCATP00000006720 LOC105584562 LOC105584562 ENSCATP00000006523 ENSCATP00000006523 MBTPS1 MBTPS1 LOC105588523 LOC105588523 MS4A6A MS4A6A ENSCATP00000005514 ENSCATP00000005514 MREG MREG EIF3M EIF3M CES1 CES1 MRPS36 MRPS36 SPINK8 SPINK8 LOC105578248 LOC105578248 SPRR3 SPRR3 VNN2 VNN2 SMARCD1 SMARCD1 RAB3GAP2 RAB3GAP2 CLEC7A CLEC7A JAML JAML TMEM60 TMEM60 CXCR4 CXCR4 NFKBIZ NFKBIZ TBXAS1 TBXAS1 MTIF3 MTIF3 CXCL12 CXCL12 ENSCATP00000001543 ENSCATP00000001543 LMAN1 LMAN1 LOC105574019 LOC105574019 TNF TNF CD8A CD8A FCRL1 FCRL1 TBX6 TBX6 NR1D2 NR1D2 PPM1M PPM1M ENSCATP00000000002 ENSCATP00000000002
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPR18G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. (331 aa)
NSL1NSL1 component of MIS12 kinetochore complex. (281 aa)
TAGLNTransgelin; Belongs to the calponin family. (210 aa)
NCR3Natural cytotoxicity triggering receptor 3. (180 aa)
C1RLComplement C1r subcomponent like; Belongs to the peptidase S1 family. (526 aa)
CAMK2N2Calcium/calmodulin dependent protein kinase II inhibitor 2. (79 aa)
VPS29Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (214 aa)
MRPS15Uncharacterized protein; Belongs to the universal ribosomal protein uS15 family. (253 aa)
SPATA2LSpermatogenesis associated 2 like. (424 aa)
DDB1Damage specific DNA binding protein 1. (1143 aa)
CD34CD34 molecule. (385 aa)
LCKTyrosine-protein kinase. (540 aa)
TCF19Transcription factor 19. (345 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (309 aa)
RASGRP1RAS guanyl releasing protein 1. (837 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa)
TLR7Toll-like receptor 7; Belongs to the Toll-like receptor family. (1049 aa)
AASDHPPTAminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase. (309 aa)
HLA-EMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (356 aa)
STAMBPL1STAM binding protein like 1. (461 aa)
LECT2Leukocyte cell derived chemotaxin 2. (151 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
GINS2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa)
LOC105582733Uncharacterized protein. (431 aa)
LARP7La ribonucleoprotein domain family member 7. (581 aa)
TNFRSF10DTNF receptor superfamily member 10d. (383 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (153 aa)
MR1Major histocompatibility complex, class I-related; Belongs to the MHC class I family. (302 aa)
TNIP1TNFAIP3 interacting protein 1. (637 aa)
ESF1ESF1 nucleolar pre-rRNA processing protein homolog. (849 aa)
FASTumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity). (331 aa)
TLR9TIR domain-containing protein. (1033 aa)
FASTKFas activated serine/threonine kinase. (549 aa)
SF3B2Splicing factor 3b subunit 2. (895 aa)
GOLT1BGolgi transport 1B. (138 aa)
FBXO8F-box protein 8. (319 aa)
CSF2Colony stimulating factor 2. (144 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PRPF19Pre-mRNA processing factor 19. (512 aa)
CXCL13C-X-C motif chemokine. (109 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (831 aa)
CLEC4CC-type lectin domain family 4 member C. (166 aa)
OLFML3Olfactomedin like 3. (406 aa)
LOC105600181SCY domain-containing protein. (114 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
ZNF75AZinc finger protein 75a. (296 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2745 aa)
VMACVimentin type intermediate filament associated coiled-coil protein. (169 aa)
LTFLactotransferrin; Belongs to the transferrin family. (684 aa)
SIPA1Signal-induced proliferation-associated 1. (1042 aa)
SEPTIN10Septin 10; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (544 aa)
CCL22C-C motif chemokine ligand 22. (93 aa)
MYNNMyoneurin. (610 aa)
PLA2G7Platelet-activating factor acetylhydrolase. (439 aa)
ENSCATP00000036547Phosducin domain-containing protein. (246 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
TSPAN7Tetraspanin. (265 aa)
ENSCATP00000035508Phosducin domain-containing protein. (233 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
HMCESAbasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (355 aa)
ENSCATP00000034919Ig-like domain-containing protein. (264 aa)
KIF26BKinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2109 aa)
MS4A6EMembrane spanning 4-domains A6E. (241 aa)
EEF2Tr-type G domain-containing protein. (858 aa)
POU2AF1POU class 2 homeobox associating factor 1. (257 aa)
STAMBPSTAM binding protein. (424 aa)
ARRB1Arrestin beta 1. (418 aa)
LOC105600182SCY domain-containing protein. (114 aa)
ENSCATP00000033319Uncharacterized protein. (66 aa)
ACKR1Atypical chemokine receptor 1 (Duffy blood group). (336 aa)
ABOABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase. (360 aa)
ANPEPAminopeptidase. (968 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
CD200R1LCD200 receptor 1 like. (271 aa)
ENSCATP00000031459Protein kinase domain-containing protein. (311 aa)
MED30Mediator complex subunit 30. (178 aa)
CD44CD44 molecule (Indian blood group). (742 aa)
NRTNNeurturin. (197 aa)
CBX2Chromobox 2. (530 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (462 aa)
LOC105583051Prohibitin. (299 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
ACAD9Acyl-CoA dehydrogenase family member 9. (605 aa)
LRRC25Leucine rich repeat containing 25. (307 aa)
DSTYKDual serine/threonine and tyrosine protein kinase. (931 aa)
ENSCATP00000029349Uncharacterized protein. (163 aa)
LAMTOR3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
NEK9NIMA related kinase 9. (976 aa)
CRLF2Cytokine receptor like factor 2. (330 aa)
ENSCATP00000028799Uncharacterized protein. (139 aa)
GSTK1Glutathione S-transferase kappa. (226 aa)
ENSCATP00000028631TRASH domain-containing protein. (71 aa)
TMEM18Transmembrane protein 18. (140 aa)
NXT2Nuclear transport factor 2 like export factor 2. (197 aa)
LOC105587027Protein kinase domain-containing protein. (250 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (265 aa)
BTLAB and T lymphocyte associated. (289 aa)
SIGLEC10Uncharacterized protein. (698 aa)
SLIRPSRA stem-loop interacting RNA binding protein. (112 aa)
TOR1AIP1Torsin 1A interacting protein 1. (600 aa)
CMC2COX assembly mitochondrial protein. (92 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (118 aa)
CCKBRCholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family. (513 aa)
ENSCATP00000024947Uncharacterized protein. (303 aa)
ENSCATP00000024886Oligosaccharyltransferase complex subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All s [...] (184 aa)
GPNMBGlycoprotein nmb. (561 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (285 aa)
ENSCATP00000024269Phosducin domain-containing protein. (228 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
RSL24D1Ribosomal L24 domain containing 1. (163 aa)
PROM1Prominin 1. (864 aa)
LOC105573012Uncharacterized protein. (220 aa)
OSTCOligosaccharyltransferase complex subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All s [...] (171 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (596 aa)
LOC105600307Ig-like domain-containing protein. (268 aa)
NSD3Nuclear receptor binding SET domain protein 3. (1438 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa)
LOC105599822Calponin-homology (CH) domain-containing protein. (188 aa)
ELOCElongin C. (112 aa)
CD8BIg-like domain-containing protein. (213 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (154 aa)
TIRAPTIR domain containing adaptor protein. (239 aa)
IL5RAInterleukin 5 receptor subunit alpha. (420 aa)
ERLIN1ER lipid raft associated 1. (348 aa)
TMEM107Transmembrane protein 107. (140 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (677 aa)
RCAN3RCAN family member 3. (241 aa)
NUSAP1Uncharacterized protein. (393 aa)
RASA3RAS p21 protein activator 3. (810 aa)
ICMTProtein-S-isoprenylcysteine O-methyltransferase. (284 aa)
CD86CD86 molecule. (329 aa)
NUP98Nucleoporin 98. (1817 aa)
MS4A7Membrane spanning 4-domains A7. (240 aa)
CLEC4DC-type lectin domain family 4 member D. (215 aa)
LOC105575605Ig-like domain-containing protein. (263 aa)
CYBBCytochrome b-245 beta chain. (468 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (403 aa)
ENSCATP00000019220Uncharacterized protein. (192 aa)
SS18L2SS18 like 2. (57 aa)
PHF23PHD finger protein 23. (403 aa)
TNFRSF11ATNF receptor superfamily member 11a. (616 aa)
SMIM8Small integral membrane protein 8. (97 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (534 aa)
FAM162AFamily with sequence similarity 162 member A. (155 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1156 aa)
CD80CD80 molecule. (288 aa)
UBTD2Ubiquitin domain containing 2. (234 aa)
DEDDDeath effector domain containing. (347 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
CD83CD83 molecule. (205 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa)
TSC1TSC complex subunit 1. (1167 aa)
ENSCATP00000017574Uncharacterized protein. (96 aa)
ENSCATP00000017128Prohibitin. (87 aa)
ADAM19ADAM metallopeptidase domain 19. (918 aa)
SDHAF3Uncharacterized protein. (125 aa)
IL31Interleukin 31. (163 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
TMUB1Transmembrane and ubiquitin like domain containing 1. (246 aa)
CCL18C-C motif chemokine. (88 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa)
LOC105579876Protein kinase domain-containing protein. (298 aa)
IRF7Interferon regulatory factor 7. (517 aa)
RB1CC1RB1 inducible coiled-coil 1. (1594 aa)
CYP21A2Cytochrome P450 family 21 subfamily A member 2; Belongs to the cytochrome P450 family. (399 aa)
KTN1Kinectin 1. (1357 aa)
LOC105572204Uncharacterized protein. (102 aa)
IL13Interleukin 13. (146 aa)
APCAPC regulator of WNT signaling pathway. (2861 aa)
PDCL3Phosducin domain-containing protein. (241 aa)
ENSCATP00000012999Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (115 aa)
DUSP22Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
MSANTD4Myb/SANT DNA binding domain containing 4 with coiled-coils. (345 aa)
MS4A4AMembrane spanning 4-domains A4A. (239 aa)
TAOK3TAO kinase 3. (886 aa)
GAB3GRB2 associated binding protein 3. (587 aa)
METTL5Methyltransferase like 5. (265 aa)
SLC7A5Solute carrier family 7 member 5. (507 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (284 aa)
SIGLEC9Sialic acid binding Ig like lectin 9. (464 aa)
TADA2ATranscriptional adapter. (443 aa)
ENSCATP00000010534Sld5 domain-containing protein. (165 aa)
NFATC1Nuclear factor of activated T cells 1. (973 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (770 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (668 aa)
SDHCUncharacterized protein. (169 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (637 aa)
RAP1GDS1Rap1 GTPase-GDP dissociation stimulator 1. (608 aa)
LOC105587411COesterase domain-containing protein. (295 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (721 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
ENSCATP00000008703PWWP domain-containing protein. (523 aa)
ZDHHC4Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (344 aa)
CD40CD40 molecule. (278 aa)
GATA1GATA binding protein 1. (413 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (270 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
FUNDC2FUN14 domain containing 2. (189 aa)
ICOSLGUncharacterized protein. (302 aa)
LRP8LDL receptor related protein 8. (960 aa)
ENSCATP00000007212Uncharacterized protein. (156 aa)
ENY2-2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (86 aa)
DLSTDihydrolipoamide S-succinyltransferase. (454 aa)
ENSCATP00000006720Oligosaccharyltransferase complex subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All s [...] (140 aa)
LOC105584562Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
ENSCATP00000006523Prohibitin. (286 aa)
MBTPS1Membrane bound transcription factor peptidase, site 1. (1052 aa)
LOC105588523COesterase domain-containing protein. (545 aa)
MS4A6AMembrane spanning 4-domains A6A. (276 aa)
ENSCATP00000005514Uncharacterized protein. (241 aa)
MREGMelanoregulin. (214 aa)
EIF3MEukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (374 aa)
CES1Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (567 aa)
MRPS36Uncharacterized protein. (103 aa)
SPINK8Serine peptidase inhibitor, Kazal type 8 (putative). (97 aa)
LOC105578248Uncharacterized protein. (443 aa)
SPRR3Small proline rich protein 3. (169 aa)
VNN2Vanin 2. (520 aa)
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa)
RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2. (1412 aa)
CLEC7AC-type lectin domain containing 7A. (256 aa)
JAMLJunction adhesion molecule like. (394 aa)
TMEM60Transmembrane protein 60. (133 aa)
CXCR4C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (408 aa)
NFKBIZNFKB inhibitor zeta. (719 aa)
TBXAS1Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (580 aa)
MTIF3Mitochondrial translational initiation factor 3. (278 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
ENSCATP00000001543Ig-like domain-containing protein. (271 aa)
LMAN1Lectin, mannose binding 1. (510 aa)
LOC105574019Tr-type G domain-containing protein. (828 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
CD8ACD8a molecule. (276 aa)
FCRL1Fc receptor like 1. (429 aa)
TBX6T-box transcription factor 6. (436 aa)
NR1D2Nuclear receptor subfamily 1 group D member 2. (580 aa)
PPM1MProtein phosphatase, Mg2+/Mn2+ dependent 1M. (474 aa)
ENSCATP00000000002Uncharacterized protein. (65 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
Server load: low (20%) [HD]