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| | ENSCATP00000012773 | DHFR domain-containing protein. (189 aa) |
| | LOC105576414 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa) |
| | MOB4 | MOB family member 4, phocein. (225 aa) |
| | MPL | MPL proto-oncogene, thrombopoietin receptor. (646 aa) |
| | MLLT3 | MLLT3 super elongation complex subunit. (568 aa) |
| | ENSCATP00000012807 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (175 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | LOC105595720 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ENSCATP00000001452 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (98 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1139 aa) |
| | CXCR4 | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (408 aa) |
| | CNTN6 | Contactin 6. (1029 aa) |
| | AFDN | Afadin, adherens junction formation factor. (1834 aa) |
| | NPM1 | Nucleophosmin 1. (294 aa) |
| | ACP5 | Tartrate-resistant acid phosphatase type 5. (325 aa) |
| | KLF3 | Kruppel like factor 3. (345 aa) |
| | LOC105579060 | HATPase_c domain-containing protein. (641 aa) |
| | FLT3 | Fms related tyrosine kinase 3. (741 aa) |
| | ENSCATP00000003984 | Uncharacterized protein. (276 aa) |
| | ATP7A | ATPase copper transporting alpha. (1500 aa) |
| | ENSCATP00000004470 | Uncharacterized protein. (92 aa) |
| | RUNX1T1 | RUNX1 partner transcriptional co-repressor 1. (632 aa) |
| | LATS1 | Large tumor suppressor kinase 1. (1179 aa) |
| | MLX | MAX dimerization protein MLX. (298 aa) |
| | LOC105588083 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | LOC105589984 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ENSCATP00000007553 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (179 aa) |
| | ENSCATP00000008104 | Homeobox domain-containing protein. (251 aa) |
| | JAK2 | Tyrosine-protein kinase. (1137 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (270 aa) |
| | GATA1 | GATA binding protein 1. (413 aa) |
| | ENSCATP00000008701 | Uncharacterized protein. (188 aa) |
| | NUDT2 | Nudix hydrolase 2. (147 aa) |
| | CASP3 | Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa) |
| | ENSCATP00000011131 | TCTP domain-containing protein; Belongs to the TCTP family. (102 aa) |
| | DTX1 | Deltex E3 ubiquitin ligase 1. (622 aa) |
| | CD247 | CD247 molecule. (165 aa) |
| | FGFR1OP2 | FGFR1 oncogene partner 2. (253 aa) |
| | RARA | Retinoic acid receptor alpha. (478 aa) |
| | RDH5 | Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa) |
| | CD34 | CD34 molecule. (385 aa) |
| | LCK | Tyrosine-protein kinase. (540 aa) |
| | TOP1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | BTG3 | BTG anti-proliferation factor 3. (291 aa) |
| | LRRC74A | Leucine rich repeat containing 74A. (488 aa) |
| | CST7 | Cystatin F. (145 aa) |
| | SETD2 | SET domain containing 2, histone lysine methyltransferase. (2529 aa) |
| | MOB2 | MOB kinase activator 2. (268 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa) |
| | ENSCATP00000041581 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa) |
| | ICA1 | Islet cell autoantigen 1. (513 aa) |
| | LOC105571593 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CD28 | CD28 molecule. (234 aa) |
| | ENSCATP00000039328 | Nucleoplasmin domain-containing protein. (209 aa) |
| | ENSCATP00000039241 | Uncharacterized protein. (287 aa) |
| | CSF2 | Colony stimulating factor 2. (144 aa) |
| | ENSCATP00000038453 | Uncharacterized protein; Belongs to the peptidase C14A family. (262 aa) |
| | HSP90AA1 | Heat shock protein 90 alpha family class A member 1. (831 aa) |
| | FIP1L1 | Fip1 domain-containing protein. (615 aa) |
| | MLN | Motilin. (114 aa) |
| | EPOR | Erythropoietin receptor; Receptor for erythropoietin. (508 aa) |
| | LOC105575645 | Nucleoplasmin domain-containing protein. (210 aa) |
| | ENSCATP00000037036 | Uncharacterized protein. (82 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (214 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | IL3 | Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (151 aa) |
| | MCOLN1 | Mucolipin 1. (531 aa) |
| | ENSCATP00000035908 | Uncharacterized protein. (247 aa) |
| | ENSCATP00000035826 | Uncharacterized protein. (286 aa) |
| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) |
| | RBL1 | RB transcriptional corepressor like 1. (1108 aa) |
| | MPRIP | Uncharacterized protein. (2312 aa) |
| | AFF1 | AF4/FMR2 family member 1. (1221 aa) |
| | ENSCATP00000031513 | Uncharacterized protein. (295 aa) |
| | SAV1 | Salvador family WW domain containing protein 1. (412 aa) |
| | ANXA5 | Annexin. (312 aa) |
| | ZAP70 | Tyrosine-protein kinase. (619 aa) |
| | CD4 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (462 aa) |
| | DNAJC24 | DnaJ heat shock protein family (Hsp40) member C24. (150 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | ENSCATP00000028238 | Homeobox domain-containing protein. (277 aa) |
| | MARCHF4 | Membrane associated ring-CH-type finger 4. (411 aa) |
| | ETV6 | ETS variant 6. (452 aa) |
| | ENSCATP00000040848 | TCTP domain-containing protein; Belongs to the TCTP family. (108 aa) |
| | PTK7 | Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa) |
| | RUNX2 | RUNX family transcription factor 2. (635 aa) |
| | ENSCATP00000026830 | Uncharacterized protein. (233 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa) |
| | DERL2 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (265 aa) |
| | PRAM1 | PML-RARA regulated adaptor molecule 1. (676 aa) |
| | TXNIP | Thioredoxin interacting protein. (391 aa) |
| | ENSCATP00000024481 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (95 aa) |
| | HSP90AB1 | Heat shock protein 90 alpha family class B member 1. (724 aa) |
| | PBX4 | PBX homeobox 4. (377 aa) |
| | SIT1 | Signaling threshold regulating transmembrane adaptor 1. (200 aa) |
| | NUP88 | Nucleoporin 88. (741 aa) |
| | TFRC | Transferrin receptor. (755 aa) |
| | MOB1A | MOB kinase activator 1A. (216 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa) |
| | LOC105588756 | Caspase recruitment domain family member 17. (110 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (154 aa) |
| | CD19 | CD19 molecule. (531 aa) |
| | ITGA2B | Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1090 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2573 aa) |
| | NPTN | Neuroplastin. (398 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | ENSCATP00000020372 | annotation not available (67 aa) |
| | NCAM1 | Neural cell adhesion molecule 1. (1108 aa) |
| | ENSCATP00000019895 | DHFR domain-containing protein. (132 aa) |
| | HBM | Hemoglobin subunit mu; Belongs to the globin family. (141 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa) |
| | OGA | O-GlcNAcase. (900 aa) |
| | TNFSF13B | TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa) |
| | CASP12 | Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (408 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | ENSCATP00000017090 | DHFR domain-containing protein. (153 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa) |
| | SASS6 | SAS-6 centriolar assembly protein. (657 aa) |
| | NUP214 | Nucleoporin 214. (2089 aa) |
| | ENSCATP00000016131 | Uncharacterized protein. (244 aa) |
| | TPT1 | Tumor protein, translationally-controlled 1; Belongs to the TCTP family. (196 aa) |
| | TOM1 | Target of myb1 membrane trafficking protein; Belongs to the TOM1 family. (493 aa) |
| | PBX1 | PBX homeobox 1. (430 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (441 aa) |
| | ATL2 | Atlastin GTPase 2. (583 aa) |
| | AR | Androgen receptor. (897 aa) |
| | ENSCATP00000012880 | DHFR domain-containing protein. (145 aa) |
| | SDHAF2 | Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (166 aa) |
| | ENSCATP00000040749 | Uncharacterized protein. (189 aa) |
| | ENSCATP00000040578 | Nucleoplasmin domain-containing protein. (217 aa) |
| | ITIH4 | Inter-alpha-trypsin inhibitor heavy chain 4. (935 aa) |
| | HMHB1 | Histocompatibility minor HB-1. (41 aa) |
| | E2F4 | E2F transcription factor 4. (427 aa) |
| | DHFR | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa) |
| | FCER2 | Fc fragment of IgE receptor II. (321 aa) |
| | ENSCATP00000012642 | Uncharacterized protein. (67 aa) |
