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PPAT PPAT MAT1A MAT1A ENSCATP00000000240 ENSCATP00000000240 ENSCATP00000000323 ENSCATP00000000323 LOC105576414 LOC105576414 LIPT1 LIPT1 MAT2A MAT2A SHMT1 SHMT1 AGXT AGXT FPGS FPGS ACCSL ACCSL MTHFD1 MTHFD1 THNSL1 THNSL1 HYI HYI ALDH1L1 ALDH1L1 ALDH1L2 ALDH1L2 ENSCATP00000005166 ENSCATP00000005166 BHMT BHMT ENSCATP00000005781 ENSCATP00000005781 LOC105592420 LOC105592420 SDSL SDSL ENSCATP00000007553 ENSCATP00000007553 ENSCATP00000007813 ENSCATP00000007813 MTFMT MTFMT ENSCATP00000008183 ENSCATP00000008183 MTHFR MTHFR LOC105573394 LOC105573394 LIPT2 LIPT2 ENSCATP00000010114 ENSCATP00000010114 HDDC3 HDDC3 ENSCATP00000010800 ENSCATP00000010800 ENSCATP00000010880 ENSCATP00000010880 DNMT3B DNMT3B ENSCATP00000012114 ENSCATP00000012114 ENSCATP00000012807 ENSCATP00000012807 ENSCATP00000012880 ENSCATP00000012880 PSPH PSPH DNMT1 DNMT1 THNSL2 THNSL2 MTR MTR GGH GGH ST20-MTHFS ST20-MTHFS ENSCATP00000017090 ENSCATP00000017090 SLC46A1 SLC46A1 IBA57 IBA57 BCAT2 BCAT2 ENSCATP00000019895 ENSCATP00000019895 GLYCTK GLYCTK CTBP1 CTBP1 BTD BTD PAICS PAICS GRHPR GRHPR PDPR PDPR LIAS LIAS GART GART MECOM MECOM ENSCATP00000029419 ENSCATP00000029419 CBS CBS PHGDH PHGDH LOC105573483 LOC105573483 SRR SRR HACL1 HACL1 GLS2 GLS2 ADSL ADSL AHCYL2 AHCYL2 GLDC GLDC ENSCATP00000034510 ENSCATP00000034510 AHCYL1 AHCYL1 AMT AMT CORO2A CORO2A MTHFD2 MTHFD2 CORO2B CORO2B ENSCATP00000036574 ENSCATP00000036574 SDS SDS FTCD FTCD ENSCATP00000038044 ENSCATP00000038044 BHMT2 BHMT2 ADSS1 ADSS1 TRDMT1 TRDMT1 MTHFD1L MTHFD1L HLCS HLCS SHMT2 SHMT2 CTH CTH CTBP2 CTBP2 BCAT1 BCAT1 AHCY AHCY PSAT1 PSAT1 MAT2B MAT2B ART3 ART3 MTHFD2L MTHFD2L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PPATAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (517 aa)
MAT1AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (396 aa)
ENSCATP00000000240Uncharacterized protein. (130 aa)
ENSCATP00000000323Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (430 aa)
LOC105576414DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
LIPT1Lipoyltransferase 1. (373 aa)
MAT2AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (395 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (483 aa)
AGXTSerine--pyruvate aminotransferase. (414 aa)
FPGSFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (587 aa)
ACCSL1-aminocyclopropane-1-carboxylate synthase homolog (inactive) like. (495 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (978 aa)
THNSL1Threonine synthase like 1. (743 aa)
HYIHydroxypyruvate isomerase (putative). (317 aa)
ALDH1L1Aldehyde dehydrogenase 1 family member L1; Belongs to the aldehyde dehydrogenase family. (992 aa)
ALDH1L210-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
ENSCATP00000005166Josephin domain-containing protein. (106 aa)
BHMTBetaine--homocysteine S-methyltransferase. (470 aa)
ENSCATP00000005781Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (368 aa)
LOC105592420Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (173 aa)
SDSLSerine dehydratase like. (329 aa)
ENSCATP00000007553DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (179 aa)
ENSCATP00000007813Uncharacterized protein. (287 aa)
MTFMTMitochondrial methionyl-tRNA formyltransferase. (381 aa)
ENSCATP00000008183Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (146 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (697 aa)
LOC105573394S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (346 aa)
LIPT2Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family. (231 aa)
ENSCATP00000010114Uncharacterized protein. (248 aa)
HDDC3HD domain containing 3. (179 aa)
ENSCATP00000010800Uncharacterized protein. (151 aa)
ENSCATP00000010880Uncharacterized protein. (333 aa)
DNMT3BDNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (862 aa)
ENSCATP00000012114Aminotran_5 domain-containing protein. (341 aa)
ENSCATP00000012807DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (175 aa)
ENSCATP00000012880DHFR domain-containing protein. (145 aa)
PSPHPhosphoserine phosphatase. (225 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1632 aa)
THNSL2Threonine synthase like 2. (458 aa)
MTRMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1268 aa)
GGHFolate gamma-glutamyl hydrolase. (299 aa)
ST20-MTHFS5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (231 aa)
ENSCATP00000017090DHFR domain-containing protein. (153 aa)
SLC46A1Solute carrier family 46 member 1. (544 aa)
IBA57Iron-sulfur cluster assembly factor IBA57. (357 aa)
BCAT2Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (432 aa)
ENSCATP00000019895DHFR domain-containing protein. (132 aa)
GLYCTKGlycerate kinase. (523 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (440 aa)
BTDBiotinidase. (573 aa)
PAICSAIRC domain-containing protein. (424 aa)
GRHPRGlyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (358 aa)
PDPRPyruvate dehydrogenase phosphatase regulatory subunit. (879 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa)
GARTTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa)
MECOMMDS1 and EVI1 complex locus. (1230 aa)
ENSCATP00000029419Uncharacterized protein. (162 aa)
CBSPALP domain-containing protein. (548 aa)
PHGDHPhosphoglycerate dehydrogenase. (545 aa)
LOC105573483Uncharacterized protein. (880 aa)
SRRSerine racemase. (339 aa)
HACL12-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (578 aa)
GLS2Glutaminase 2. (602 aa)
ADSLAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (497 aa)
AHCYL2Adenosylhomocysteinase like 2; Belongs to the adenosylhomocysteinase family. (610 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1020 aa)
ENSCATP00000034510Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (435 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
AMTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (403 aa)
CORO2ACoronin; Belongs to the WD repeat coronin family. (525 aa)
MTHFD2Uncharacterized protein. (336 aa)
CORO2BCoronin 2B. (485 aa)
ENSCATP00000036574Aminotran_5 domain-containing protein. (134 aa)
SDSSerine dehydratase. (328 aa)
FTCDFormimidoyltransferase cyclodeaminase. (541 aa)
ENSCATP00000038044Uncharacterized protein. (279 aa)
BHMT2Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. (363 aa)
ADSS1Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
TRDMT1tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (391 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (927 aa)
HLCSHolocarboxylase synthetase. (874 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
CTHCystathionine gamma-lyase. (405 aa)
CTBP2C-terminal binding protein 2. (992 aa)
BCAT1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
AHCYAdenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. (420 aa)
PSAT1Phosphoserine aminotransferase. (370 aa)
MAT2BMethionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (323 aa)
ART3NAD(P)(+)--arginine ADP-ribosyltransferase. (390 aa)
MTHFD2LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (347 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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