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CBL | Cbl proto-oncogene. (907 aa) | ||||
PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa) | ||||
KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) | ||||
SH3GL2 | SH3 domain containing GRB2 like 2, endophilin A1. (352 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa) | ||||
CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (975 aa) | ||||
CBLB | Cbl proto-oncogene B. (1027 aa) | ||||
TIE1 | Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa) | ||||
SH3GL3 | SH3 domain containing GRB2 like 3, endophilin A3. (354 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) | ||||
MST1R | Macrophage stimulating 1 receptor. (1426 aa) | ||||
ENSCATP00000005869 | Uncharacterized protein. (526 aa) | ||||
GAB1 | GRB2 associated binding protein 1. (724 aa) | ||||
PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1024 aa) | ||||
KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) | ||||
NRG4 | Neuregulin 4. (117 aa) | ||||
ENSCATP00000006855 | Uncharacterized protein. (519 aa) | ||||
PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa) | ||||
ENSCATP00000007407 | PID domain-containing protein. (502 aa) | ||||
GRAP | GRB2 related adaptor protein. (217 aa) | ||||
INSR | Tyrosine-protein kinase receptor. (1339 aa) | ||||
FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa) | ||||
ERBB2 | Receptor protein-tyrosine kinase. (1399 aa) | ||||
KLB | Klotho beta. (1044 aa) | ||||
KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) | ||||
GRB10 | Growth factor receptor bound protein 10. (593 aa) | ||||
IGF1R | Tyrosine-protein kinase receptor. (1366 aa) | ||||
FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
INSRR | Tyrosine-protein kinase receptor. (1296 aa) | ||||
ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1349 aa) | ||||
MST1 | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (711 aa) | ||||
IRS1 | Insulin receptor substrate 1. (1241 aa) | ||||
VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (409 aa) | ||||
FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) | ||||
IL34 | Interleukin 34. (242 aa) | ||||
VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (188 aa) | ||||
ANGPT1 | Angiopoietin 1. (498 aa) | ||||
ENSCATP00000016044 | Protein kinase domain-containing protein. (357 aa) | ||||
FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) | ||||
FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) | ||||
PDGFD | Platelet derived growth factor D. (370 aa) | ||||
PTPN11 | Protein tyrosine phosphatase non-receptor type 11. (552 aa) | ||||
TEK | TEK receptor tyrosine kinase. (1124 aa) | ||||
FGFR3 | Fibroblast growth factor receptor. (809 aa) | ||||
SPRY2 | Sprouty RTK signaling antagonist 2. (338 aa) | ||||
VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) | ||||
GAB2 | GRB2 associated binding protein 2. (676 aa) | ||||
SH3KBP1 | SH3 domain containing kinase binding protein 1. (665 aa) | ||||
FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) | ||||
FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) | ||||
LRIG1 | Leucine rich repeats and immunoglobulin like domains 1. (1088 aa) | ||||
ANGPT2 | Angiopoietin 2. (495 aa) | ||||
FGF11 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa) | ||||
AREG | Amphiregulin. (274 aa) | ||||
FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1362 aa) | ||||
PDGFRL | Platelet derived growth factor receptor like. (432 aa) | ||||
PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) | ||||
FGFRL1 | Fibroblast growth factor receptor like 1. (474 aa) | ||||
EPGN | Epithelial mitogen. (154 aa) | ||||
FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa) | ||||
NRG3 | Neuregulin 3. (720 aa) | ||||
S100A13 | S100 calcium binding protein A13; Belongs to the S-100 family. (98 aa) | ||||
SHC1 | SHC adaptor protein 1. (584 aa) | ||||
FRS2 | Fibroblast growth factor receptor substrate 2. (522 aa) | ||||
FGFR2 | Fibroblast growth factor receptor. (840 aa) | ||||
FGFR4 | Fibroblast growth factor receptor. (802 aa) | ||||
NRG1 | Neuregulin 1. (713 aa) | ||||
SH3GL1 | SH3 domain containing GRB2 like 1, endophilin A2. (396 aa) | ||||
BTC | Betacellulin. (171 aa) | ||||
FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) | ||||
FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa) | ||||
FRS3 | Fibroblast growth factor receptor substrate 3. (492 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1210 aa) | ||||
IDE | Insulin degrading enzyme; Belongs to the peptidase M16 family. (1019 aa) | ||||
SHC4 | SHC adaptor protein 4. (630 aa) | ||||
HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (788 aa) | ||||
PTPN1 | Tyrosine-protein phosphatase non-receptor type. (435 aa) | ||||
NTRK2 | Tyrosine-protein kinase receptor. (838 aa) | ||||
FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) | ||||
VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (421 aa) | ||||
EREG | Epiregulin. (169 aa) | ||||
EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1166 aa) | ||||
ANGPT4 | Angiopoietin 4. (503 aa) | ||||
CBLC | Cbl proto-oncogene C. (571 aa) | ||||
CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (555 aa) | ||||
FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) | ||||
SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1327 aa) | ||||
IGF2 | Insulin like growth factor 2. (236 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) | ||||
FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) | ||||
TGFA | Transforming growth factor alpha. (166 aa) | ||||
SPRY1 | Sprouty RTK signaling antagonist 1. (319 aa) | ||||
MET | MET proto-oncogene, receptor tyrosine kinase. (1404 aa) | ||||
FGFR1 | Fibroblast growth factor receptor. (820 aa) | ||||
ERBB4 | Receptor protein-tyrosine kinase. (1308 aa) | ||||
IGF1 | Insulin like growth factor 1. (208 aa) | ||||
SHC3 | SHC adaptor protein 3. (598 aa) | ||||
NTRK1 | Tyrosine-protein kinase receptor. (796 aa) | ||||
GRB2 | Growth factor receptor bound protein 2. (217 aa) | ||||
NRG2 | Neuregulin 2. (851 aa) | ||||
INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) | ||||
ENSCATP00000044421 | Uncharacterized protein. (441 aa) | ||||
KL | Klotho. (1001 aa) | ||||
PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) | ||||
LRIG3 | Leucine rich repeats and immunoglobulin like domains 3. (1119 aa) | ||||
FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) | ||||
FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa) |