(12 nodes) Mixed, incl. Schwann cell migration, and SPRE, EVH1 domain network (Cercocebus atys)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RRAS	RAS related. (218 aa)
	RASA2	RAS p21 protein activator 2. (856 aa)
	RASA3	RAS p21 protein activator 3. (810 aa)
	SPRED2	Sprouty related EVH1 domain containing 2. (432 aa)
	SHOC2	SHOC2 leucine rich repeat scaffold protein. (582 aa)
	SPRED1	Sprouty related EVH1 domain containing 1. (444 aa)
	NF1	Neurofibromin 1. (2839 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	RRAS2	RAS related 2. (204 aa)
	MRAS	Muscle RAS oncogene homolog. (208 aa)
	RASAL2	RAS protein activator like 2. (1280 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MRAS	NF1	ENSCATP00000042124	ENSCATP00000035080	Muscle RAS oncogene homolog.	Neurofibromin 1.	0.948
MRAS	PIK3CD	ENSCATP00000042124	ENSCATP00000038140	Muscle RAS oncogene homolog.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.967
MRAS	RASA2	ENSCATP00000042124	ENSCATP00000020137	Muscle RAS oncogene homolog.	RAS p21 protein activator 2.	0.944
MRAS	RASA3	ENSCATP00000042124	ENSCATP00000020156	Muscle RAS oncogene homolog.	RAS p21 protein activator 3.	0.788
MRAS	RASAL2	ENSCATP00000042124	ENSCATP00000045810	Muscle RAS oncogene homolog.	RAS protein activator like 2.	0.802
MRAS	RRAS	ENSCATP00000042124	ENSCATP00000001593	Muscle RAS oncogene homolog.	RAS related.	0.585
MRAS	RRAS2	ENSCATP00000042124	ENSCATP00000041454	Muscle RAS oncogene homolog.	RAS related 2.	0.600
MRAS	SHOC2	ENSCATP00000042124	ENSCATP00000029643	Muscle RAS oncogene homolog.	SHOC2 leucine rich repeat scaffold protein.	0.993
MRAS	SPRED1	ENSCATP00000042124	ENSCATP00000031018	Muscle RAS oncogene homolog.	Sprouty related EVH1 domain containing 1.	0.430
NF1	MRAS	ENSCATP00000035080	ENSCATP00000042124	Neurofibromin 1.	Muscle RAS oncogene homolog.	0.948
NF1	NRAS	ENSCATP00000035080	ENSCATP00000036364	Neurofibromin 1.	NRAS proto-oncogene, GTPase.	0.983
NF1	RASA2	ENSCATP00000035080	ENSCATP00000020137	Neurofibromin 1.	RAS p21 protein activator 2.	0.546
NF1	RASA3	ENSCATP00000035080	ENSCATP00000020156	Neurofibromin 1.	RAS p21 protein activator 3.	0.522
NF1	RASAL2	ENSCATP00000035080	ENSCATP00000045810	Neurofibromin 1.	RAS protein activator like 2.	0.520
NF1	RRAS	ENSCATP00000035080	ENSCATP00000001593	Neurofibromin 1.	RAS related.	0.948
NF1	RRAS2	ENSCATP00000035080	ENSCATP00000041454	Neurofibromin 1.	RAS related 2.	0.948
NF1	SPRED1	ENSCATP00000035080	ENSCATP00000031018	Neurofibromin 1.	Sprouty related EVH1 domain containing 1.	0.961
NF1	SPRED2	ENSCATP00000035080	ENSCATP00000020811	Neurofibromin 1.	Sprouty related EVH1 domain containing 2.	0.940
NRAS	NF1	ENSCATP00000036364	ENSCATP00000035080	NRAS proto-oncogene, GTPase.	Neurofibromin 1.	0.983
NRAS	PIK3CD	ENSCATP00000036364	ENSCATP00000038140	NRAS proto-oncogene, GTPase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.963