(10 nodes) Mixed, incl. Transcription factor SOX, and Mesodermal cell fate determination network (Cercocebus atys)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SOX2	SRY-box transcription factor 2. (319 aa)
	KLF4	Kruppel like factor 4. (479 aa)
	LIN28A	Lin-28 homolog A. (209 aa)
	SOX1	SRY-box transcription factor 1. (386 aa)
	ENSCATP00000008104	Homeobox domain-containing protein. (251 aa)
	SALL4	Spalt like transcription factor 4. (1053 aa)
	NACC1	Nucleus accumbens associated 1. (527 aa)
	ENSCATP00000028238	Homeobox domain-containing protein. (277 aa)
	POU5F1	POU domain protein. (360 aa)
	KLF2	Kruppel like factor 2. (355 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCATP00000008104	KLF2	ENSCATP00000008104	ENSCATP00000042244	Homeobox domain-containing protein.	Kruppel like factor 2.	0.521
ENSCATP00000008104	KLF4	ENSCATP00000008104	ENSCATP00000006108	Homeobox domain-containing protein.	Kruppel like factor 4.	0.651
ENSCATP00000008104	LIN28A	ENSCATP00000008104	ENSCATP00000006763	Homeobox domain-containing protein.	Lin-28 homolog A.	0.406
ENSCATP00000008104	NACC1	ENSCATP00000008104	ENSCATP00000022891	Homeobox domain-containing protein.	Nucleus accumbens associated 1.	0.706
ENSCATP00000008104	POU5F1	ENSCATP00000008104	ENSCATP00000032946	Homeobox domain-containing protein.	POU domain protein.	0.916
ENSCATP00000008104	SALL4	ENSCATP00000008104	ENSCATP00000013229	Homeobox domain-containing protein.	Spalt like transcription factor 4.	0.899
ENSCATP00000008104	SOX1	ENSCATP00000008104	ENSCATP00000007979	Homeobox domain-containing protein.	SRY-box transcription factor 1.	0.574
ENSCATP00000008104	SOX2	ENSCATP00000008104	ENSCATP00000004881	Homeobox domain-containing protein.	SRY-box transcription factor 2.	0.651
ENSCATP00000028238	KLF2	ENSCATP00000028238	ENSCATP00000042244	Homeobox domain-containing protein.	Kruppel like factor 2.	0.521
ENSCATP00000028238	KLF4	ENSCATP00000028238	ENSCATP00000006108	Homeobox domain-containing protein.	Kruppel like factor 4.	0.651
ENSCATP00000028238	LIN28A	ENSCATP00000028238	ENSCATP00000006763	Homeobox domain-containing protein.	Lin-28 homolog A.	0.406
ENSCATP00000028238	NACC1	ENSCATP00000028238	ENSCATP00000022891	Homeobox domain-containing protein.	Nucleus accumbens associated 1.	0.706
ENSCATP00000028238	POU5F1	ENSCATP00000028238	ENSCATP00000032946	Homeobox domain-containing protein.	POU domain protein.	0.916
ENSCATP00000028238	SALL4	ENSCATP00000028238	ENSCATP00000013229	Homeobox domain-containing protein.	Spalt like transcription factor 4.	0.899
ENSCATP00000028238	SOX1	ENSCATP00000028238	ENSCATP00000007979	Homeobox domain-containing protein.	SRY-box transcription factor 1.	0.574
ENSCATP00000028238	SOX2	ENSCATP00000028238	ENSCATP00000004881	Homeobox domain-containing protein.	SRY-box transcription factor 2.	0.574
KLF2	ENSCATP00000008104	ENSCATP00000042244	ENSCATP00000008104	Kruppel like factor 2.	Homeobox domain-containing protein.	0.521
KLF2	ENSCATP00000028238	ENSCATP00000042244	ENSCATP00000028238	Kruppel like factor 2.	Homeobox domain-containing protein.	0.521
KLF2	POU5F1	ENSCATP00000042244	ENSCATP00000032946	Kruppel like factor 2.	POU domain protein.	0.724
KLF2	SOX1	ENSCATP00000042244	ENSCATP00000007979	Kruppel like factor 2.	SRY-box transcription factor 1.	0.436